| 1 |  |  | #!/usr/bin/env python | 
            
                                                                                                            
                            
            
                                    
            
            
                | 2 |  |  | """Plot both the standard 'is_a' field and the optional 'part_of' relationship.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 3 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 4 |  |  | from __future__ import print_function | 
            
                                                                                                            
                            
            
                                    
            
            
                | 5 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 6 |  |  | __copyright__ = "Copyright (C) 2016-2018, DV Klopfenstein, H Tang, All rights reserved." | 
            
                                                                                                            
                            
            
                                    
            
            
                | 7 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 8 |  |  | import os | 
            
                                                                                                            
                            
            
                                    
            
            
                | 9 |  |  | import sys | 
            
                                                                                                            
                            
            
                                    
            
            
                | 10 |  |  | from goatools.test_data.wr_subobo import WrSubObo | 
            
                                                                                                            
                            
            
                                    
            
            
                | 11 |  |  | from goatools.base import download_go_basic_obo | 
            
                                                                                                            
                            
            
                                    
            
            
                | 12 |  |  | from goatools.obo_parser import GODag | 
            
                                                                                                            
                            
            
                                    
            
            
                | 13 |  |  | from goatools.gosubdag.gosubdag import GoSubDag | 
            
                                                                                                            
                            
            
                                    
            
            
                | 14 |  |  | from goatools.gosubdag.plot.gosubdag_plot import GoSubDagPlot | 
            
                                                                                                            
                            
            
                                    
            
            
                | 15 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 16 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 17 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 18 |  |  | REPO = os.path.join(os.path.dirname(os.path.abspath(__file__)), "../") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 19 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 20 |  |  | NAME2GOIDS = { | 
            
                                                                                                            
                            
            
                                    
            
            
                | 21 |  |  |     'smell': set([ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 22 |  |  |         "GO:0007608",   # sensory perception of smell | 
            
                                                                                                            
                            
            
                                    
            
            
                | 23 |  |  |         "GO:0050911"]), # detection of chemical stimulus involved in sensory perception of smell | 
            
                                                                                                            
                            
            
                                    
            
            
                | 24 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 25 |  |  |     'secretory':set([ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 26 |  |  |         "GO:0030141",   # CC 20 L06 D07 AC  P... p... secretory granule | 
            
                                                                                                            
                            
            
                                    
            
            
                | 27 |  |  |         "GO:0034774"]), # CC  8 L05 D06 ABD P... .... secretory granule lumen | 
            
                                                                                                            
                            
            
                                    
            
            
                | 28 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 29 |  |  |     # MISSING Edge source(GO:0007507); target(GO:0072359) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 30 |  |  |     # MISSING:  GO:0061371  # BP 0 L06 D06 B P p determination of heart left/right asymmetry | 
            
                                                                                                            
                            
            
                                    
            
            
                | 31 |  |  |     # ERROR:    GO:0007507 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 32 |  |  |     'heartjogging':set([ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 33 |  |  |         "GO:0003304",  # BP 0 L06 D06 A P . myocardial epithelial involution in heart jogging | 
            
                                                                                                            
                            
            
                                    
            
            
                | 34 |  |  |         "GO:0003146"]) # BP 0 L05 D07 A P p heart jogging | 
            
                                                                                                            
                            
            
                                    
            
            
                | 35 |  |  | } | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 36 |  |  |  | 
            
                                                                        
                            
            
                                    
            
            
                | 37 |  |  | def test_plot_part_of(): | 
            
                                                                        
                            
            
                                    
            
            
                | 38 |  |  |     """Plot both the standard 'is_a' field and the 'part_of' relationship.""" | 
            
                                                                        
                            
            
                                    
            
            
                | 39 |  |  |     fout_log = "plot_relationship_part_of.log" | 
            
                                                                        
                            
            
                                    
            
            
                | 40 |  |  |     obj = _Run() | 
            
                                                                        
                            
            
                                    
            
            
                | 41 |  |  |     names = NAME2GOIDS | 
            
                                                                        
                            
            
                                    
            
            
                | 42 |  |  |     # names = ["heartjogging"] | 
            
                                                                        
                            
            
                                    
            
            
                | 43 |  |  |     with open(fout_log, 'w') as prt: | 
            
                                                                        
                            
            
                                    
            
            
                | 44 |  |  |         for name in names: | 
            
                                                                        
                            
            
                                    
            
            
                | 45 |  |  |             goids = NAME2GOIDS[name] | 
            
                                                                        
                            
            
                                    
            
            
                | 46 |  |  |             obj.plot_all(goids, name, prt) | 
            
                                                                        
                            
            
                                    
            
            
                | 47 |  |  |         print("  WROTE: {LOG}\n".format(LOG=fout_log)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 48 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 49 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 50 |  |  | # pylint: disable=too-few-public-methods | 
            
                                                                                                            
                            
            
                                    
            
            
                | 51 |  |  | class _Run(object): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 52 |  |  |     """Holds data and steps for this test.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 53 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 54 |  |  |     obopat = "../goatools/data/{NAME}.obo" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 55 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 56 |  |  |     def __init__(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 57 |  |  |         _fin_obo = os.path.join(REPO, "go-basic.obo") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 58 |  |  |         self.go2obj = GODag(_fin_obo, optional_attrs=['relationship']) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 59 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 60 |  |  |     def plot_all(self, goids, name, prt=sys.stdout): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 61 |  |  |         """Create plots with various numbers of relationships.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 62 |  |  |         prt.write("\nCreate GoSubDag not loading any relationship") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 63 |  |  |         gosubdag_orig = GoSubDag(goids, self.go2obj, relationships=False, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 64 |  |  |         gosubdag_orig.prt_goids(gosubdag_orig.go2obj, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 65 |  |  |         prt.write("{N} GO IDS".format(N=len(gosubdag_orig.go2obj))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 66 |  |  |         gopltdag = GoSubDagPlot(gosubdag_orig, mark_alt_id=True) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 67 |  |  |         gopltdag.plt_dag(os.path.join(REPO, "a_relationship_{NAME}_r0.png".format(NAME=name))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 68 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 69 |  |  |         # goids.update(['GO:0007507'], ['GO:0072359']) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 70 |  |  |         prt.write("\nCreate GoSubDag while loading only the 'part_of' relationship") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 71 |  |  |         gosubdag = GoSubDag(goids, self.go2obj, relationships=['part_of'], prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 72 |  |  |         gosubdag.prt_goids(gosubdag.go2obj, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 73 |  |  |         prt.write("{N} GO IDS".format(N=len(gosubdag.go2obj))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 74 |  |  |         gopltdag = GoSubDagPlot(gosubdag, mark_alt_id=True) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 75 |  |  |         prt.write("GO SOURCES:") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 76 |  |  |         gosubdag.prt_goids(gosubdag.go_sources, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 77 |  |  |         gopltdag.plt_dag(os.path.join(REPO, "a_relationship_{NAME}_partof.png".format(NAME=name))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 78 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 79 |  |  |         prt.write("\nCreate GoSubDag while loading all relationships") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 80 |  |  |         gosubdag = GoSubDag(goids, self.go2obj, relationships=True, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 81 |  |  |         prt.write("ALL {N} GO IDS:".format(N=len(gosubdag.go2obj))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 82 |  |  |         gosubdag.prt_goids(gosubdag.go2obj, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 83 |  |  |         prt.write("2 GO SOURCES:") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 84 |  |  |         gosubdag.prt_goids(gosubdag.go_sources, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 85 |  |  |         goids_new = set(gosubdag.go2obj).difference(set(gosubdag_orig.go2obj)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 86 |  |  |         go2color = {go:'#d5ffff' for go in goids_new} | 
            
                                                                                                            
                            
            
                                    
            
            
                | 87 |  |  |         prt.write("{N} NEW GO IDS:".format(N=len(goids_new))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 88 |  |  |         gosubdag.prt_goids(goids_new, prt=prt) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 89 |  |  |         prt.write("{N} GO IDS".format(N=len(gosubdag.go2obj))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 90 |  |  |         gopltdag = GoSubDagPlot(gosubdag, mark_alt_id=True, go2color=go2color) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 91 |  |  |         gopltdag.plt_dag(os.path.join(REPO, "a_relationship_{NAME}_r1.png".format(NAME=name))) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 92 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 93 |  |  |     def wr_subobo(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 94 |  |  |         """Write a subset obo to be used for testing.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 95 |  |  |         # Load GO-DAG: Load optional 'relationship' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 96 |  |  |         for name, goids in NAME2GOIDS.items(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 97 |  |  |             fout_obo = self.get_obo_name(name) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 98 |  |  |             fin_obo = os.path.join(REPO, "go-basic.obo") | 
            
                                                                                                            
                            
            
                                    
            
            
                | 99 |  |  |             download_go_basic_obo(fin_obo, prt=sys.stdout, loading_bar=None) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 100 |  |  |             obj = WrSubObo(fin_obo, optional_attrs=['relationship']) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 101 |  |  |             # obj = WrSubObo(fin_obo) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 102 |  |  |             obj.wrobo(fout_obo, goids) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 103 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 104 |  |  |     def get_obo_name(self, name): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 105 |  |  |         """Get the name of the obo for a small subset.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 106 |  |  |         return os.path.join(REPO, self.obopat.format(NAME=name)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 107 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 108 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 109 |  |  | if __name__ == '__main__': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 110 |  |  |     #_Run().wr_subobo() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 111 |  |  |     test_plot_part_of() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 112 |  |  |  | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 113 |  |  | # Copyright (C) 2016-2018, DV Klopfenstein, H Tang, All rights reserved. | 
            
                                                        
            
                                    
            
            
                | 114 |  |  |  |