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                """Manage GOATOOLS GOEA namedtuples."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                __copyright__ = "Copyright (C) 2010-2018, H Tang et al., All rights reserved."  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                __author__ = "DV Klopfenstein"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                import collections as cx  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from goatools.rpt.nts_xfrm import MgrNts  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                def get_study_items(goea_results):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    """Get all study items found in a GOATOOLS GOEA (e.g., geneids)."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    return MgrNtGOEAs(goea_results).get_study_items()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                def get_goea_nts_prt(goea_results, **kws):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    """Get namedtuples containing user-specified (or default) data from GOATOOLS GOEA results."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    return MgrNtGOEAs(goea_results).get_goea_nts_prt(**kws)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                class MgrNtGOEAs(object):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    """Manage GOATOOLS GOEA namedtuples."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def __init__(self, goea_results):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        self.goea_results = list(goea_results)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def get_study_items(self):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Get all study items (e.g., geneids)."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        study_items = set()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        for rec in self.goea_results:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            study_items |= rec.study_items  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        return study_items  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def get_nts_strpval(self, fmt="{:8.2e}"): | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Given GOEA namedtuples, return nts w/P-value in string format."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        objntmgr = MgrNts(self.goea_results)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        dcts = objntmgr.init_dicts()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        pval_flds = set(k for k in self._get_fieldnames(next(iter(self.goea_results))) if k[:2] == 'p_')  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        for fld_float in pval_flds:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            fld_str = "s_" + fld_float[2:]  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            objntmgr.add_f2str(dcts, fld_float, fld_str, fmt)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        return objntmgr.mknts(dcts)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def get_goea_nts_prt(self, fldnames=None, **usr_kws):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Return list of namedtuples removing fields which are redundant or verbose."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        kws = usr_kws.copy()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if 'not_fldnames' not in kws:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            kws['not_fldnames'] = ['goterm', 'parents', 'children', 'id']  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if 'rpt_fmt' not in kws:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            kws['rpt_fmt'] = True  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        return self.get_goea_nts_all(fldnames, **kws)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def get_goea_nts_all(self, fldnames=None, **kws):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Get namedtuples containing user-specified (or default) data from GOEA results.  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            Reformats data from GOEnrichmentRecord objects into lists of  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            namedtuples so the generic table writers may be used.  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        # kws: prt_if indent itemid2name(study_items)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        data_nts = [] # A list of namedtuples containing GOEA results  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if not self.goea_results:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            return data_nts  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        keep_if = kws.get('keep_if', None) | 
            
            
                                                                        
                            
            
                                    
            
            
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                        rpt_fmt = kws.get('rpt_fmt', False) | 
            
            
                                                                        
                            
            
                                    
            
            
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                        indent = kws.get('indent', False) | 
            
            
                                                                        
                            
            
                                    
            
            
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                        # I. FIELD (column) NAMES  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        not_fldnames = kws.get('not_fldnames', None) | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if fldnames is None:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            fldnames = self._get_fieldnames(self.goea_results[0])  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        # Ia. Explicitly exclude specific fields from named tuple  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if not_fldnames is not None:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            fldnames = [f for f in fldnames if f not in not_fldnames]  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        nttyp = cx.namedtuple("NtGoeaResults", " ".join(fldnames)) | 
            
            
                                                                        
                            
            
                                    
            
            
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                        goid_idx = fldnames.index("GO") if 'GO' in fldnames else None | 
            
            
                                                                        
                            
            
                                    
            
            
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                        # II. Loop through GOEA results stored in a GOEnrichmentRecord object  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        for goerec in self.goea_results:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            vals = self._get_field_values(goerec, fldnames, rpt_fmt, kws.get('itemid2name', None)) | 
            
            
                                                                        
                            
            
                                    
            
            
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                            if indent:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                                vals[goid_idx] = "".join([goerec.get_indent_dots(), vals[goid_idx]])  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            ntobj = nttyp._make(vals)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            if keep_if is None or keep_if(goerec):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                                data_nts.append(ntobj)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        return data_nts  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    @staticmethod  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def _get_field_values(item, fldnames, rpt_fmt=None, itemid2name=None):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Return fieldnames and values of either a namedtuple or GOEnrichmentRecord."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if hasattr(item, "_fldsdefprt"): # Is a GOEnrichmentRecord  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            return item.get_field_values(fldnames, rpt_fmt, itemid2name)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if hasattr(item, "_fields"): # Is a namedtuple  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            return [getattr(item, f) for f in fldnames]  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    @staticmethod  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    def _get_fieldnames(item):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        """Return fieldnames of either a namedtuple or GOEnrichmentRecord."""  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if hasattr(item, "_fldsdefprt"): # Is a GOEnrichmentRecord  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            return item.get_prtflds_all()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if hasattr(item, "_fields"): # Is a namedtuple  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            return item._fields  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                # Copyright (C) 2010-2018, H Tang et al., All rights reserved.  | 
            
            
                                                        
            
                                    
            
            
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