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                import csv  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from pathlib import Path  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from typing import Optional  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from ..typing import TypePath  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from ..transforms import Transform  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from ..download import download_and_extract_archive  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from .. import SubjectsDataset, Subject, ScalarImage, LabelMap  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                class EPISURG(SubjectsDataset):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    `EPISURG`_ is a clinical dataset of :math:`T_1`-weighted MRI from 430  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    epileptic patients who underwent resective brain surgery at the National  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    Hospital of Neurology and Neurosurgery (Queen Square, London, United  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    Kingdom) between 1990 and 2018.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    The dataset comprises 430 postoperative MRI. The corresponding preoperative  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    MRI is present for 268 subjects.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    Three human raters segmented the resection cavity on partially overlapping  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    subsets of EPISURG.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    If you use this dataset for your research, you agree with the *Data use  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    agreement* presented at the EPISURG entry on the `UCL Research Data  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    Repository <EPISURG>`_ and you must cite the corresponding publications.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    .. _EPISURG: https://doi.org/10.5522/04/9996158.v1  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        root: Root directory to which the dataset will be downloaded.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        transform: An instance of  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            :class:`~torchio.transforms.transform.Transform`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        download: If set to ``True``, will download the data into :attr:`root`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    .. warning:: The size of this dataset is multiple GB.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        If you set :attr:`download` to ``True``, it will take some time  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        to be downloaded if it is not already present.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    data_url = 'https://s3-eu-west-1.amazonaws.com/pstorage-ucl-2748466690/26153588/EPISURG.zip'  # noqa: E501  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    md5 = '5ec5831a2c6fbfdc8489ba2910a6504b'  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
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                    def __init__(  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            self,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            root: TypePath,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            transform: Optional[Transform] = None,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            download: bool = False,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            **kwargs,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            ):  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        root = Path(root).expanduser().absolute()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        if download:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                            self._download(root)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        subjects_list = self._get_subjects_list(root)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        self.kwargs = kwargs  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        super().__init__(subjects_list, transform=transform, **kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _check_exists(root, modalities):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        for modality in modalities:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            modality_dir = root / modality  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            if not modality_dir.is_dir():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                exists = False  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                break  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            exists = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        return exists  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _get_subjects_list(root):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        episurg_dir = root / 'EPISURG'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        subjects_dir = episurg_dir / 'subjects'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        csv_path = episurg_dir / 'subjects.csv'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        with open(csv_path) as csvfile:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            reader = csv.DictReader(csvfile)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            subjects = []  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            for row in reader:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                subject_id = row['Subject']  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                subject_dir = subjects_dir / subject_id  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                subject_dict = { | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    'subject_id': subject_id,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    'hemisphere': row['Hemisphere'],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    'surgery_type': row['Type'],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                }  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                preop_dir = subject_dir / 'preop'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                preop_paths = list(preop_dir.glob('*preop*')) | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                assert len(preop_paths) <= 1  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                if preop_paths:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    subject_dict['preop_mri'] = ScalarImage(preop_paths[0])  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                postop_dir = subject_dir / 'postop'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                postop_path = list(postop_dir.glob('*postop-t1mri*'))[0] | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                subject_dict['postop_mri'] = ScalarImage(postop_path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                for seg_path in postop_dir.glob('*seg*'): | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    seg_id = seg_path.name[-8]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    subject_dict[f'seg_{seg_id}'] = LabelMap(seg_path) | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                subjects.append(Subject(**subject_dict))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        return subjects  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _download(self, root):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        """Download the EPISURG data if it does not exist already."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        if (root / 'EPISURG').is_dir():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            return  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        root.mkdir(exist_ok=True, parents=True)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        download_and_extract_archive(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            self.data_url,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            download_root=root,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            md5=self.md5,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        (root / 'EPISURG.zip').unlink()  # cleanup  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _glob_subjects(self, string):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        subjects = []  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        for subject in self._subjects:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            for image_name in subject:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                if string in image_name:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    subjects.append(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                    break  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        return subjects  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _get_labeled_subjects(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        return self._glob_subjects('seg') | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _get_paired_subjects(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    124
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                        return self._glob_subjects('preop') | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    def _get_subset(self, subjects):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        dataset = SubjectsDataset(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            subjects,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    129
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                            transform=self._transform,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    130
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                            **(self.kwargs),  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        return dataset  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    133
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    134
                 | 
                                    
                                                     | 
                
                 | 
                    def get_labeled(self) -> SubjectsDataset:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    135
                 | 
                                    
                                                     | 
                
                 | 
                        """Get dataset from subjects with manual annotations."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    136
                 | 
                                    
                                                     | 
                
                 | 
                        return self._get_subset(self._get_labeled_subjects())  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    137
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    138
                 | 
                                    
                                                     | 
                
                 | 
                    def get_unlabeled(self) -> SubjectsDataset:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    139
                 | 
                                    
                                                     | 
                
                 | 
                        """Get dataset from subjects without manual annotations."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    140
                 | 
                                    
                                                     | 
                
                 | 
                        subjects = [  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    141
                 | 
                                    
                                                     | 
                
                 | 
                            s for s in self._subjects  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    142
                 | 
                                    
                                                     | 
                
                 | 
                            if s not in self._get_labeled_subjects()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    143
                 | 
                                    
                                                     | 
                
                 | 
                        ]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    144
                 | 
                                    
                                                     | 
                
                 | 
                        return self._get_subset(subjects)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    145
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    146
                 | 
                                    
                                                     | 
                
                 | 
                    def get_paired(self) -> SubjectsDataset:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    147
                 | 
                                    
                                                     | 
                
                 | 
                        """Get dataset from subjects with pre- and post-op MRI."""  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    148
                 | 
                                    
                                                     | 
                
                 | 
                        return self._get_subset(self._get_paired_subjects())  | 
            
            
                                                        
            
                                    
            
            
                | 
                    149
                 | 
                                    
                                                     | 
                
                 | 
                 |