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                    1
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                import warnings  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    2
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                from pathlib import Path  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    3
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                from typing import Any, Dict, Tuple, Optional, Union, Sequence, List  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    4
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                    5
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                import torch  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    6
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                import humanize  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    7
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                import numpy as np  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    8
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                from PIL import Image as ImagePIL  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    9
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                import nibabel as nib  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    10
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                import SimpleITK as sitk  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from ..utils import (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    nib_to_sitk,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    14
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                    get_rotation_and_spacing_from_affine,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    15
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                    get_stem,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    16
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                    ensure_4d,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    check_uint_to_int,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    18
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                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    19
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                from ..torchio import (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    20
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                    TypeData,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    21
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                    TypePath,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    22
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                    TypeTripletInt,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    23
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                    TypeTripletFloat,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    24
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                    DATA,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    25
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                    TYPE,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    26
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                    AFFINE,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    27
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                    PATH,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    28
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                    STEM,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    29
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                    INTENSITY,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    30
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                    LABEL,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    31
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                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    32
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                from .io import read_image, write_image  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    33
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                    35
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                PROTECTED_KEYS = DATA, AFFINE, TYPE, PATH, STEM  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    36
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                TypeBound = Tuple[float, float]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    37
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                TypeBounds = Tuple[TypeBound, TypeBound, TypeBound]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    40
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                class Image(dict):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    41
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                    r"""TorchIO image.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    42
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                    43
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                    For information about medical image orientation, check out `NiBabel docs`_,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    44
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                    the `3D Slicer wiki`_, `Graham Wideman's website`_, `FSL docs`_ or  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    45
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                    `SimpleITK docs`_.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    46
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                    47
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                    Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    48
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                        path: Path to a file or sequence of paths to files that can be read by  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    49
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                            :mod:`SimpleITK` or :mod:`nibabel`, or to a directory containing  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    50
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                            DICOM files. If :attr:`tensor` is given, the data in  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    51
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                            :attr:`path` will not be read.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    52
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                            If a sequence of paths is given, data  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    53
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                            will be concatenated on the channel dimension so spatial  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    54
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                            dimensions must match.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    55
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                        type: Type of image, such as :attr:`torchio.INTENSITY` or  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    56
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                            :attr:`torchio.LABEL`. This will be used by the transforms to  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    57
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                            decide whether to apply an operation, or which interpolation to use  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    58
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                            when resampling. For example, `preprocessing`_ and `augmentation`_  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    59
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                            intensity transforms will only be applied to images with type  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    60
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                            :attr:`torchio.INTENSITY`. Spatial transforms will be applied to  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    61
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                            all types, and nearest neighbor interpolation is always used to  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    62
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                            resample images with type :attr:`torchio.LABEL`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    63
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                            The type :attr:`torchio.SAMPLING_MAP` may be used with instances of  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    64
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                            :class:`~torchio.data.sampler.weighted.WeightedSampler`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    65
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                        tensor: If :attr:`path` is not given, :attr:`tensor` must be a 4D  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    66
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                            :class:`torch.Tensor` or NumPy array with dimensions  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    67
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                            :math:`(C, W, H, D)`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    68
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                        affine: If :attr:`path` is not given, :attr:`affine` must be a  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    69
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                            :math:`4 \times 4` NumPy array. If ``None``, :attr:`affine` is an  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    70
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                            identity matrix.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    71
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                        check_nans: If ``True``, issues a warning if NaNs are found  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    72
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                            in the image. If ``False``, images will not be checked for the  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    73
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                            presence of NaNs.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    74
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                        **kwargs: Items that will be added to the image dictionary, e.g.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    75
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                            acquisition parameters.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    76
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                    77
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                    TorchIO images are `lazy loaders`_, i.e. the data is only loaded from disk  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    78
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                    when needed.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    79
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                    80
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                    Example:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    81
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                        >>> import torchio as tio  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    82
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                        >>> image = tio.ScalarImage('t1.nii.gz')  # subclass of Image | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    83
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                        >>> image  # not loaded yet  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    84
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                        ScalarImage(path: t1.nii.gz; type: intensity)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    85
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                        >>> times_two = 2 * image.data  # data is loaded and cached here  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    86
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                        >>> image  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    87
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                        ScalarImage(shape: (1, 256, 256, 176); spacing: (1.00, 1.00, 1.00); orientation: PIR+; memory: 44.0 MiB; type: intensity)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    88
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                        >>> image.save('doubled_image.nii.gz') | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    89
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                    90
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                    .. _lazy loaders: https://en.wikipedia.org/wiki/Lazy_loading  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    91
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                    .. _preprocessing: https://torchio.readthedocs.io/transforms/preprocessing.html#intensity  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    92
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                    .. _augmentation: https://torchio.readthedocs.io/transforms/augmentation.html#intensity  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    93
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                    .. _NiBabel docs: https://nipy.org/nibabel/image_orientation.html  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    94
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                    .. _3D Slicer wiki: https://www.slicer.org/wiki/Coordinate_systems  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    95
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                    .. _FSL docs: https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/Orientation%20Explained  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    96
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                    .. _SimpleITK docs: https://simpleitk.readthedocs.io/en/master/fundamentalConcepts.html  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    97
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                    .. _Graham Wideman's website: http://www.grahamwideman.com/gw/brain/orientation/orientterms.htm  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    98
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    99
                 | 
                                    
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                    def __init__(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    100
                 | 
                                    
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                            self,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    101
                 | 
                                    
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                            path: Union[TypePath, Sequence[TypePath], None] = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    102
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                            type: str = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    103
                 | 
                                    
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                            tensor: Optional[TypeData] = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    104
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                            affine: Optional[TypeData] = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    105
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                            check_nans: bool = False,  # removed by ITK by default  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    106
                 | 
                                    
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                            channels_last: bool = False,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    107
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                            **kwargs: Dict[str, Any],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    108
                 | 
                                    
                                                     | 
                
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                            ):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    109
                 | 
                                    
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                        self.check_nans = check_nans  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    110
                 | 
                                    
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                        self.channels_last = channels_last  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    111
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    112
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                        if type is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    113
                 | 
                                    
                                                     | 
                
                 | 
                            warnings.warn(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    114
                 | 
                                    
                                                     | 
                
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                                'Not specifying the image type is deprecated and will be'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    115
                 | 
                                    
                                                     | 
                
                 | 
                                ' mandatory in the future. You can probably use tio.ScalarImage'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    116
                 | 
                                    
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                                'or LabelMap instead', DeprecationWarning,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    117
                 | 
                                    
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                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    118
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                            type = INTENSITY  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    119
                 | 
                                    
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    120
                 | 
                                    
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                        if path is None and tensor is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    121
                 | 
                                    
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                 | 
                            raise ValueError('A value for path or tensor must be given') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    122
                 | 
                                    
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                        self._loaded = False  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    123
                 | 
                                    
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    124
                 | 
                                    
                                                     | 
                
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                        tensor = self._parse_tensor(tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    125
                 | 
                                    
                                                     | 
                
                 | 
                        affine = self._parse_affine(affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    126
                 | 
                                    
                                                     | 
                
                 | 
                        if tensor is not None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    127
                 | 
                                    
                                                     | 
                
                 | 
                            self.data = tensor  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    128
                 | 
                                    
                                                     | 
                
                 | 
                            self.affine = affine  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    129
                 | 
                                    
                                                     | 
                
                 | 
                            self._loaded = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    130
                 | 
                                    
                                                     | 
                
                 | 
                        for key in PROTECTED_KEYS:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    131
                 | 
                                    
                                                     | 
                
                 | 
                            if key in kwargs:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    132
                 | 
                                    
                                                     | 
                
                 | 
                                message = f'Key "{key}" is reserved. Use a different one' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    133
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    134
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    135
                 | 
                                    
                                                     | 
                
                 | 
                        super().__init__(**kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    136
                 | 
                                    
                                                     | 
                
                 | 
                        self.path = self._parse_path(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    137
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    138
                 | 
                                    
                                                     | 
                
                 | 
                        self[PATH] = '' if self.path is None else str(self.path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    139
                 | 
                                    
                                                     | 
                
                 | 
                        self[STEM] = '' if self.path is None else get_stem(self.path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    140
                 | 
                                    
                                                     | 
                
                 | 
                        self[TYPE] = type  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    141
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    142
                 | 
                                    
                                                     | 
                
                 | 
                    def __repr__(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    143
                 | 
                                    
                                                     | 
                
                 | 
                        properties = []  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    144
                 | 
                                    
                                                     | 
                
                 | 
                        if self._loaded:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    145
                 | 
                                    
                                                     | 
                
                 | 
                            properties.extend([  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    146
                 | 
                                    
                                                     | 
                
                 | 
                                f'shape: {self.shape}', | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    147
                 | 
                                    
                                                     | 
                
                 | 
                                f'spacing: {self.get_spacing_string()}', | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    148
                 | 
                                    
                                                     | 
                
                 | 
                                f'orientation: {"".join(self.orientation)}+', | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    149
                 | 
                                    
                                                     | 
                
                 | 
                                f'memory: {humanize.naturalsize(self.memory, binary=True)}', | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    150
                 | 
                                    
                                                     | 
                
                 | 
                            ])  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    151
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    152
                 | 
                                    
                                                     | 
                
                 | 
                            properties.append(f'path: "{self.path}"') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    153
                 | 
                                    
                                                     | 
                
                 | 
                        properties.append(f'dtype: {self.data.type()}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    154
                 | 
                                    
                                                     | 
                
                 | 
                        properties = '; '.join(properties)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    155
                 | 
                                    
                                                     | 
                
                 | 
                        string = f'{self.__class__.__name__}({properties})' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    156
                 | 
                                    
                                                     | 
                
                 | 
                        return string  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    157
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    158
                 | 
                                    
                                                     | 
                
                 | 
                    def __getitem__(self, item):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    159
                 | 
                                    
                                                     | 
                
                 | 
                        if item in (DATA, AFFINE):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    160
                 | 
                                    
                                                     | 
                
                 | 
                            if item not in self:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    161
                 | 
                                    
                                                     | 
                
                 | 
                                self.load()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    162
                 | 
                                    
                                                     | 
                
                 | 
                        return super().__getitem__(item)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    163
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    164
                 | 
                                    
                                                     | 
                
                 | 
                    def __array__(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    165
                 | 
                                    
                                                     | 
                
                 | 
                        return self[DATA].numpy()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    166
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    167
                 | 
                                    
                                                     | 
                
                 | 
                    def __copy__(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    168
                 | 
                                    
                                                     | 
                
                 | 
                        kwargs = dict(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    169
                 | 
                                    
                                                     | 
                
                 | 
                            tensor=self.data,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    170
                 | 
                                    
                                                     | 
                
                 | 
                            affine=self.affine,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    171
                 | 
                                    
                                                     | 
                
                 | 
                            type=self.type,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    172
                 | 
                                    
                                                     | 
                
                 | 
                            path=self.path,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    173
                 | 
                                    
                                                     | 
                
                 | 
                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    174
                 | 
                                    
                                                     | 
                
                 | 
                        for key, value in self.items():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    175
                 | 
                                    
                                                     | 
                
                 | 
                            if key in PROTECTED_KEYS: continue  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    176
                 | 
                                    
                                                     | 
                
                 | 
                            kwargs[key] = value  # should I copy? deepcopy?  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    177
                 | 
                                    
                                                     | 
                
                 | 
                        return self.__class__(**kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    178
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    179
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    180
                 | 
                                    
                                                     | 
                
                 | 
                    def data(self) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    181
                 | 
                                    
                                                     | 
                
                 | 
                        """Tensor data. Same as :class:`Image.tensor`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    182
                 | 
                                    
                                                     | 
                
                 | 
                        return self[DATA]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    183
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    184
                 | 
                                    
                                                     | 
                
                 | 
                    @data.setter  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    185
                 | 
                                    
                                                     | 
                
                 | 
                    def data(self, tensor: TypeData):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    186
                 | 
                                    
                                                     | 
                
                 | 
                        self[DATA] = self._parse_tensor(tensor, none_ok=False)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    187
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    188
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    189
                 | 
                                    
                                                     | 
                
                 | 
                    def tensor(self) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    190
                 | 
                                    
                                                     | 
                
                 | 
                        """Tensor data. Same as :class:`Image.data`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    191
                 | 
                                    
                                                     | 
                
                 | 
                        return self.data  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    192
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    193
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    194
                 | 
                                    
                                                     | 
                
                 | 
                    def affine(self) -> np.ndarray:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    195
                 | 
                                    
                                                     | 
                
                 | 
                        """Affine matrix to transform voxel indices into world coordinates."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    196
                 | 
                                    
                                                     | 
                
                 | 
                        return self[AFFINE]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    197
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    198
                 | 
                                    
                                                     | 
                
                 | 
                    @affine.setter  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    199
                 | 
                                    
                                                     | 
                
                 | 
                    def affine(self, matrix):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    200
                 | 
                                    
                                                     | 
                
                 | 
                        self[AFFINE] = self._parse_affine(matrix)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    201
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    202
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    203
                 | 
                                    
                                                     | 
                
                 | 
                    def type(self) -> str:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    204
                 | 
                                    
                                                     | 
                
                 | 
                        return self[TYPE]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    205
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    206
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    207
                 | 
                                    
                                                     | 
                
                 | 
                    def shape(self) -> Tuple[int, int, int, int]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    208
                 | 
                                    
                                                     | 
                
                 | 
                        """Tensor shape as :math:`(C, W, H, D)`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    209
                 | 
                                    
                                                     | 
                
                 | 
                        return tuple(self.data.shape)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    210
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    211
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    212
                 | 
                                    
                                                     | 
                
                 | 
                    def spatial_shape(self) -> TypeTripletInt:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    213
                 | 
                                    
                                                     | 
                
                 | 
                        """Tensor spatial shape as :math:`(W, H, D)`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    214
                 | 
                                    
                                                     | 
                
                 | 
                        return self.shape[1:]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    215
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    216
                 | 
                                    
                                                     | 
                
                 | 
                    def check_is_2d(self) -> None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    217
                 | 
                                    
                                                     | 
                
                 | 
                        if not self.is_2d():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    218
                 | 
                                    
                                                     | 
                
                 | 
                            message = f'Image is not 2D. Spatial shape: {self.spatial_shape}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    219
                 | 
                                    
                                                     | 
                
                 | 
                            raise RuntimeError(message)  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    220
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    221
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    222
                 | 
                                    
                                                     | 
                
                 | 
                    def height(self) -> int:  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    223
                 | 
                                    
                                                     | 
                
                 | 
                        """Image height, if 2D."""  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    224
                 | 
                                    
                                                     | 
                
                 | 
                        self.check_is_2d()  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    225
                 | 
                                    
                                                     | 
                
                 | 
                        return self.spatial_shape[1]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    226
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    227
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    228
                 | 
                                    
                                                     | 
                
                 | 
                    def width(self) -> int:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    229
                 | 
                                    
                                                     | 
                
                 | 
                        """Image width, if 2D."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    230
                 | 
                                    
                                                     | 
                
                 | 
                        self.check_is_2d()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    231
                 | 
                                    
                                                     | 
                
                 | 
                        return self.spatial_shape[0]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    232
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    233
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    234
                 | 
                                    
                                                     | 
                
                 | 
                    def orientation(self) -> Tuple[str, str, str]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    235
                 | 
                                    
                                                     | 
                
                 | 
                        """Orientation codes."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    236
                 | 
                                    
                                                     | 
                
                 | 
                        return nib.aff2axcodes(self.affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    237
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    238
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    239
                 | 
                                    
                                                     | 
                
                 | 
                    def spacing(self) -> Tuple[float, float, float]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    240
                 | 
                                    
                                                     | 
                
                 | 
                        """Voxel spacing in mm."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    241
                 | 
                                    
                                                     | 
                
                 | 
                        _, spacing = get_rotation_and_spacing_from_affine(self.affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    242
                 | 
                                    
                                                     | 
                
                 | 
                        return tuple(spacing)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    243
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    244
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    245
                 | 
                                    
                                                     | 
                
                 | 
                    def memory(self) -> float:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    246
                 | 
                                    
                                                     | 
                
                 | 
                        """Number of Bytes that the tensor takes in the RAM."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    247
                 | 
                                    
                                                     | 
                
                 | 
                        return np.prod(self.shape) * 4  # float32, i.e. 4 bytes per voxel  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    248
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    249
                 | 
                                    
                                                     | 
                
                 | 
                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    250
                 | 
                                    
                                                     | 
                
                 | 
                    def bounds(self) -> np.ndarray:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    251
                 | 
                                    
                                                     | 
                
                 | 
                        """Position of centers of voxels in smallest and largest coordinates."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    252
                 | 
                                    
                                                     | 
                
                 | 
                        ini = 0, 0, 0  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    253
                 | 
                                    
                                                     | 
                
                 | 
                        fin = np.array(self.spatial_shape) - 1  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    254
                 | 
                                    
                                                     | 
                
                 | 
                        point_ini = nib.affines.apply_affine(self.affine, ini)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    255
                 | 
                                    
                                                     | 
                
                 | 
                        point_fin = nib.affines.apply_affine(self.affine, fin)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    256
                 | 
                                    
                                                     | 
                
                 | 
                        return np.array((point_ini, point_fin))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    257
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    258
                 | 
                                    
                                                     | 
                
                 | 
                    def axis_name_to_index(self, axis: str) -> int:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    259
                 | 
                                    
                                                     | 
                
                 | 
                        """Convert an axis name to an axis index.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    260
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    261
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    262
                 | 
                                    
                                                     | 
                
                 | 
                            axis: Possible inputs are ``'Left'``, ``'Right'``, ``'Anterior'``,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    263
                 | 
                                    
                                                     | 
                
                 | 
                                ``'Posterior'``, ``'Inferior'``, ``'Superior'``. Lower-case  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    264
                 | 
                                    
                                                     | 
                
                 | 
                                versions and first letters are also valid, as only the first  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    265
                 | 
                                    
                                                     | 
                
                 | 
                                letter will be used.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    266
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    267
                 | 
                                    
                                                     | 
                
                 | 
                        .. note:: If you are working with animals, you should probably use  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    268
                 | 
                                    
                                                     | 
                
                 | 
                            ``'Superior'``, ``'Inferior'``, ``'Anterior'`` and ``'Posterior'``  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    269
                 | 
                                    
                                                     | 
                
                 | 
                            for ``'Dorsal'``, ``'Ventral'``, ``'Rostral'`` and ``'Caudal'``,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    270
                 | 
                                    
                                                     | 
                
                 | 
                            respectively.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    271
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    272
                 | 
                                    
                                                     | 
                
                 | 
                        .. note:: If your images are 2D, you can use ``'Top'``, ``'Bottom'``,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    273
                 | 
                                    
                                                     | 
                
                 | 
                            ``'Left'`` and ``'Right'``.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    274
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    275
                 | 
                                    
                                                     | 
                
                 | 
                        # Top and bottom are used for the vertical 2D axis as the use of  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    276
                 | 
                                    
                                                     | 
                
                 | 
                        # Height vs Horizontal might be ambiguous  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    277
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    278
                 | 
                                    
                                                     | 
                
                 | 
                        if not isinstance(axis, str):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    279
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError('Axis must be a string') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    280
                 | 
                                    
                                                     | 
                
                 | 
                        axis = axis[0].upper()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    281
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    282
                 | 
                                    
                                                     | 
                
                 | 
                        # Generally, TorchIO tensors are (C, W, H, D)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    283
                 | 
                                    
                                                     | 
                
                 | 
                        if axis in 'TB':  # Top, Bottom  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    284
                 | 
                                    
                                                     | 
                
                 | 
                            return -2  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    285
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    286
                 | 
                                    
                                                     | 
                
                 | 
                            try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    287
                 | 
                                    
                                                     | 
                
                 | 
                                index = self.orientation.index(axis)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    288
                 | 
                                    
                                                     | 
                
                 | 
                            except ValueError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    289
                 | 
                                    
                                                     | 
                
                 | 
                                index = self.orientation.index(self.flip_axis(axis))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    290
                 | 
                                    
                                                     | 
                
                 | 
                            # Return negative indices so that it does not matter whether we  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    291
                 | 
                                    
                                                     | 
                
                 | 
                            # refer to spatial dimensions or not  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    292
                 | 
                                    
                                                     | 
                
                 | 
                            index = -3 + index  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    293
                 | 
                                    
                                                     | 
                
                 | 
                            return index  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    294
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    295
                 | 
                                    
                                                     | 
                
                 | 
                    # flake8: noqa: E701  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    296
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    297
                 | 
                                    
                                                     | 
                
                 | 
                    def flip_axis(axis: str) -> str:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    298
                 | 
                                    
                                                     | 
                
                 | 
                        if axis == 'R': return 'L'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    299
                 | 
                                    
                                                     | 
                
                 | 
                        elif axis == 'L': return 'R'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    300
                 | 
                                    
                                                     | 
                
                 | 
                        elif axis == 'A': return 'P'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    301
                 | 
                                    
                                                     | 
                
                 | 
                        elif axis == 'P': return 'A'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    302
                 | 
                                    
                                                     | 
                
                 | 
                        elif axis == 'I': return 'S'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    303
                 | 
                                    
                                                     | 
                
                 | 
                        elif axis == 'S': return 'I'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    304
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    305
                 | 
                                    
                                                     | 
                
                 | 
                            values = ', '.join('LRPAISTB') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    306
                 | 
                                    
                                                     | 
                
                 | 
                            message = f'Axis not understood. Please use one of: {values}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    307
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    308
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    309
                 | 
                                    
                                                     | 
                
                 | 
                    def get_spacing_string(self) -> str:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    310
                 | 
                                    
                                                     | 
                
                 | 
                        strings = [f'{n:.2f}' for n in self.spacing] | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    311
                 | 
                                    
                                                     | 
                
                 | 
                        string = f'({", ".join(strings)})' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    312
                 | 
                                    
                                                     | 
                
                 | 
                        return string  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    313
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    314
                 | 
                                    
                                                     | 
                
                 | 
                    def get_bounds(self) -> TypeBounds:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    315
                 | 
                                    
                                                     | 
                
                 | 
                        """Get minimum and maximum world coordinates occupied by the image."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    316
                 | 
                                    
                                                     | 
                
                 | 
                        first_index = 3 * (-0.5,)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    317
                 | 
                                    
                                                     | 
                
                 | 
                        last_index = np.array(self.spatial_shape) - 0.5  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    318
                 | 
                                    
                                                     | 
                
                 | 
                        first_point = nib.affines.apply_affine(self.affine, first_index)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    319
                 | 
                                    
                                                     | 
                
                 | 
                        last_point = nib.affines.apply_affine(self.affine, last_index)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    320
                 | 
                                    
                                                     | 
                
                 | 
                        array = np.array((first_point, last_point))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    321
                 | 
                                    
                                                     | 
                
                 | 
                        bounds_x, bounds_y, bounds_z = array.T.tolist()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    322
                 | 
                                    
                                                     | 
                
                 | 
                        return bounds_x, bounds_y, bounds_z  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    323
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    324
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    325
                 | 
                                    
                                                     | 
                
                 | 
                    def _parse_single_path(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    326
                 | 
                                    
                                                     | 
                
                 | 
                            path: TypePath  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    327
                 | 
                                    
                                                     | 
                
                 | 
                            ) -> Path:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    328
                 | 
                                    
                                                     | 
                
                 | 
                        try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    329
                 | 
                                    
                                                     | 
                
                 | 
                            path = Path(path).expanduser()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    330
                 | 
                                    
                                                     | 
                
                 | 
                        except TypeError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    331
                 | 
                                    
                                                     | 
                
                 | 
                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    332
                 | 
                                    
                                                     | 
                
                 | 
                                f'Expected type str or Path but found {path} with ' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    333
                 | 
                                    
                                                     | 
                
                 | 
                                f'{type(path)} instead' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    334
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    335
                 | 
                                    
                                                     | 
                
                 | 
                            raise TypeError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    336
                 | 
                                    
                                                     | 
                
                 | 
                        except RuntimeError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    337
                 | 
                                    
                                                     | 
                
                 | 
                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    338
                 | 
                                    
                                                     | 
                
                 | 
                                f'Conversion to path not possible for variable: {path}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    339
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    340
                 | 
                                    
                                                     | 
                
                 | 
                            raise RuntimeError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    341
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    342
                 | 
                                    
                                                     | 
                
                 | 
                        if not (path.is_file() or path.is_dir()):   # might be a dir with DICOM  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    343
                 | 
                                    
                                                     | 
                
                 | 
                            raise FileNotFoundError(f'File not found: "{path}"') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    344
                 | 
                                    
                                                     | 
                
                 | 
                        return path  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    345
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    346
                 | 
                                    
                                                     | 
                
                 | 
                    def _parse_path(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    347
                 | 
                                    
                                                     | 
                
                 | 
                            self,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    348
                 | 
                                    
                                                     | 
                
                 | 
                            path: Union[TypePath, Sequence[TypePath]]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    349
                 | 
                                    
                                                     | 
                
                 | 
                            ) -> Union[Path, List[Path]]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    350
                 | 
                                    
                                                     | 
                
                 | 
                        if path is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    351
                 | 
                                    
                                                     | 
                
                 | 
                            return None  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    352
                 | 
                                    
                                                     | 
                
                 | 
                        if isinstance(path, (str, Path)):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    353
                 | 
                                    
                                                     | 
                
                 | 
                            return self._parse_single_path(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    354
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    355
                 | 
                                    
                                                     | 
                
                 | 
                            return [self._parse_single_path(p) for p in path]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    356
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    357
                 | 
                                    
                                                     | 
                
                 | 
                    def _parse_tensor(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    358
                 | 
                                    
                                                     | 
                
                 | 
                            self,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    359
                 | 
                                    
                                                     | 
                
                 | 
                            tensor: TypeData,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    360
                 | 
                                    
                                                     | 
                
                 | 
                            none_ok: bool = True,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    361
                 | 
                                    
                                                     | 
                
                 | 
                            ) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    362
                 | 
                                    
                                                     | 
                
                 | 
                        if tensor is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    363
                 | 
                                    
                                                     | 
                
                 | 
                            if none_ok:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    364
                 | 
                                    
                                                     | 
                
                 | 
                                return None  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    365
                 | 
                                    
                                                     | 
                
                 | 
                            else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    366
                 | 
                                    
                                                     | 
                
                 | 
                                raise RuntimeError('Input tensor cannot be None') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    367
                 | 
                                    
                                                     | 
                
                 | 
                        if isinstance(tensor, np.ndarray):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    368
                 | 
                                    
                                                     | 
                
                 | 
                            tensor = check_uint_to_int(tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    369
                 | 
                                    
                                                     | 
                
                 | 
                            tensor = torch.from_numpy(tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    370
                 | 
                                    
                                                     | 
                
                 | 
                        elif not isinstance(tensor, torch.Tensor):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    371
                 | 
                                    
                                                     | 
                
                 | 
                            message = 'Input tensor must be a PyTorch tensor or NumPy array'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    372
                 | 
                                    
                                                     | 
                
                 | 
                            raise TypeError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    373
                 | 
                                    
                                                     | 
                
                 | 
                        if tensor.ndim != 4:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    374
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError('Input tensor must be 4D') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    375
                 | 
                                    
                                                     | 
                
                 | 
                        if tensor.dtype == torch.bool:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    376
                 | 
                                    
                                                     | 
                
                 | 
                            tensor = tensor.to(torch.uint8)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    377
                 | 
                                    
                                                     | 
                
                 | 
                        if self.check_nans and torch.isnan(tensor).any():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    378
                 | 
                                    
                                                     | 
                
                 | 
                            warnings.warn(f'NaNs found in tensor', RuntimeWarning)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    379
                 | 
                                    
                                                     | 
                
                 | 
                        return tensor  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    380
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    381
                 | 
                                    
                                                     | 
                
                 | 
                    def parse_tensor_shape(self, tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    382
                 | 
                                    
                                                     | 
                
                 | 
                        return ensure_4d(tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    383
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    384
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    385
                 | 
                                    
                                                     | 
                
                 | 
                    def _parse_affine(affine: np.ndarray) -> np.ndarray:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    386
                 | 
                                    
                                                     | 
                
                 | 
                        if affine is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    387
                 | 
                                    
                                                     | 
                
                 | 
                            return np.eye(4)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    388
                 | 
                                    
                                                     | 
                
                 | 
                        if not isinstance(affine, np.ndarray):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    389
                 | 
                                    
                                                     | 
                
                 | 
                            raise TypeError(f'Affine must be a NumPy array, not {type(affine)}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    390
                 | 
                                    
                                                     | 
                
                 | 
                        if affine.shape != (4, 4):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    391
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(f'Affine shape must be (4, 4), not {affine.shape}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    392
                 | 
                                    
                                                     | 
                
                 | 
                        return affine  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    393
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    394
                 | 
                                    
                                                     | 
                
                 | 
                    def load(self) -> None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    395
                 | 
                                    
                                                     | 
                
                 | 
                        r"""Load the image from disk.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    396
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    397
                 | 
                                    
                                                     | 
                
                 | 
                        Returns:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    398
                 | 
                                    
                                                     | 
                
                 | 
                            Tuple containing a 4D tensor of size :math:`(C, W, H, D)` and a 2D  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    399
                 | 
                                    
                                                     | 
                
                 | 
                            :math:`4 \times 4` affine matrix to convert voxel indices to world  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    400
                 | 
                                    
                                                     | 
                
                 | 
                            coordinates.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    401
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    402
                 | 
                                    
                                                     | 
                
                 | 
                        if self._loaded:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    403
                 | 
                                    
                                                     | 
                
                 | 
                            return  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    404
                 | 
                                    
                                                     | 
                
                 | 
                        paths = self.path if isinstance(self.path, list) else [self.path]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    405
                 | 
                                    
                                                     | 
                
                 | 
                        tensor, affine = self.read_and_check(paths[0])  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    406
                 | 
                                    
                                                     | 
                
                 | 
                        tensors = [tensor]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    407
                 | 
                                    
                                                     | 
                
                 | 
                        for path in paths[1:]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    408
                 | 
                                    
                                                     | 
                
                 | 
                            new_tensor, new_affine = self.read_and_check(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    409
                 | 
                                    
                                                     | 
                
                 | 
                            if not np.array_equal(affine, new_affine):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    410
                 | 
                                    
                                                     | 
                
                 | 
                                message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    411
                 | 
                                    
                                                     | 
                
                 | 
                                    'Files have different affine matrices.'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    412
                 | 
                                    
                                                     | 
                
                 | 
                                    f'\nMatrix of {paths[0]}:' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    413
                 | 
                                    
                                                     | 
                
                 | 
                                    f'\n{affine}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    414
                 | 
                                    
                                                     | 
                
                 | 
                                    f'\nMatrix of {path}:' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    415
                 | 
                                    
                                                     | 
                
                 | 
                                    f'\n{new_affine}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    416
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    417
                 | 
                                    
                                                     | 
                
                 | 
                                warnings.warn(message, RuntimeWarning)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    418
                 | 
                                    
                                                     | 
                
                 | 
                            if not tensor.shape[1:] == new_tensor.shape[1:]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    419
                 | 
                                    
                                                     | 
                
                 | 
                                message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    420
                 | 
                                    
                                                     | 
                
                 | 
                                    f'Files shape do not match, found {tensor.shape}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    421
                 | 
                                    
                                                     | 
                
                 | 
                                    f'and {new_tensor.shape}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    422
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    423
                 | 
                                    
                                                     | 
                
                 | 
                                RuntimeError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    424
                 | 
                                    
                                                     | 
                
                 | 
                            tensors.append(new_tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    425
                 | 
                                    
                                                     | 
                
                 | 
                        tensor = torch.cat(tensors)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    426
                 | 
                                    
                                                     | 
                
                 | 
                        self.data = tensor  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    427
                 | 
                                    
                                                     | 
                
                 | 
                        self.affine = affine  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    428
                 | 
                                    
                                                     | 
                
                 | 
                        self._loaded = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    429
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    430
                 | 
                                    
                                                     | 
                
                 | 
                    def read_and_check(self, path: TypePath) -> Tuple[torch.Tensor, np.ndarray]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    431
                 | 
                                    
                                                     | 
                
                 | 
                        tensor, affine = read_image(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    432
                 | 
                                    
                                                     | 
                
                 | 
                        tensor = self.parse_tensor_shape(tensor)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    433
                 | 
                                    
                                                     | 
                
                 | 
                        if self.channels_last:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    434
                 | 
                                    
                                                     | 
                
                 | 
                            tensor = tensor.permute(3, 0, 1, 2)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    435
                 | 
                                    
                                                     | 
                
                 | 
                        if self.check_nans and torch.isnan(tensor).any():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    436
                 | 
                                    
                                                     | 
                
                 | 
                            warnings.warn(f'NaNs found in file "{path}"', RuntimeWarning) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    437
                 | 
                                    
                                                     | 
                
                 | 
                        return tensor, affine  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    438
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    439
                 | 
                                    
                                                     | 
                
                 | 
                    def save(self, path: TypePath, squeeze: bool = True) -> None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    440
                 | 
                                    
                                                     | 
                
                 | 
                        """Save image to disk.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    441
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    442
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    443
                 | 
                                    
                                                     | 
                
                 | 
                            path: String or instance of :class:`pathlib.Path`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    444
                 | 
                                    
                                                     | 
                
                 | 
                            squeeze: If ``True``, singleton dimensions will be removed  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    445
                 | 
                                    
                                                     | 
                
                 | 
                                before saving.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    446
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    447
                 | 
                                    
                                                     | 
                
                 | 
                        write_image(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    448
                 | 
                                    
                                                     | 
                
                 | 
                            self[DATA],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    449
                 | 
                                    
                                                     | 
                
                 | 
                            self.affine,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    450
                 | 
                                    
                                                     | 
                
                 | 
                            path,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    451
                 | 
                                    
                                                     | 
                
                 | 
                            squeeze=squeeze,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    452
                 | 
                                    
                                                     | 
                
                 | 
                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    453
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    454
                 | 
                                    
                                                     | 
                
                 | 
                    def is_2d(self) -> bool:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    455
                 | 
                                    
                                                     | 
                
                 | 
                        return self.shape[-1] == 1  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    456
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    457
                 | 
                                    
                                                     | 
                
                 | 
                    def numpy(self) -> np.ndarray:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    458
                 | 
                                    
                                                     | 
                
                 | 
                        """Get a NumPy array containing the image data."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    459
                 | 
                                    
                                                     | 
                
                 | 
                        return np.asarray(self)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    460
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    461
                 | 
                                    
                                                     | 
                
                 | 
                    def as_sitk(self, **kwargs) -> sitk.Image:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    462
                 | 
                                    
                                                     | 
                
                 | 
                        """Get the image as an instance of :class:`sitk.Image`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    463
                 | 
                                    
                                                     | 
                
                 | 
                        return nib_to_sitk(self[DATA], self.affine, **kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    464
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    465
                 | 
                                    
                                                     | 
                
                 | 
                    def as_pil(self) -> ImagePIL:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    466
                 | 
                                    
                                                     | 
                
                 | 
                        """Get the image as an instance of :class:`PIL.Image`."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    467
                 | 
                                    
                                                     | 
                
                 | 
                        self.check_is_2d()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    468
                 | 
                                    
                                                     | 
                
                 | 
                        return ImagePIL.open(self.path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    469
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    470
                 | 
                                    
                                                     | 
                
                 | 
                    def get_center(self, lps: bool = False) -> TypeTripletFloat:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    471
                 | 
                                    
                                                     | 
                
                 | 
                        """Get image center in RAS+ or LPS+ coordinates.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    472
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    473
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    474
                 | 
                                    
                                                     | 
                
                 | 
                            lps: If ``True``, the coordinates will be in LPS+ orientation, i.e.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    475
                 | 
                                    
                                                     | 
                
                 | 
                                the first dimension grows towards the left, etc. Otherwise, the  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    476
                 | 
                                    
                                                     | 
                
                 | 
                                coordinates will be in RAS+ orientation.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    477
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    478
                 | 
                                    
                                                     | 
                
                 | 
                        size = np.array(self.spatial_shape)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    479
                 | 
                                    
                                                     | 
                
                 | 
                        center_index = (size - 1) / 2  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    480
                 | 
                                    
                                                     | 
                
                 | 
                        r, a, s = nib.affines.apply_affine(self.affine, center_index)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    481
                 | 
                                    
                                                     | 
                
                 | 
                        if lps:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    482
                 | 
                                    
                                                     | 
                
                 | 
                            return (-r, -a, s)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    483
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    484
                 | 
                                    
                                                     | 
                
                 | 
                            return (r, a, s)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    485
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    486
                 | 
                                    
                                                     | 
                
                 | 
                    def set_check_nans(self, check_nans: bool) -> None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    487
                 | 
                                    
                                                     | 
                
                 | 
                        self.check_nans = check_nans  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    488
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    489
                 | 
                                    
                                                     | 
                
                 | 
                    def plot(self, **kwargs) -> None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    490
                 | 
                                    
                                                     | 
                
                 | 
                        """Plot image."""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    491
                 | 
                                    
                                                     | 
                
                 | 
                        if self.is_2d():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    492
                 | 
                                    
                                                     | 
                
                 | 
                            self.as_pil().show()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    493
                 | 
                                    
                                                     | 
                
                 | 
                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    494
                 | 
                                    
                                                     | 
                
                 | 
                            from ..visualization import plot_volume  # avoid circular import  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    495
                 | 
                                    
                                                     | 
                
                 | 
                            plot_volume(self, **kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    496
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    497
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    498
                 | 
                                    
                                                     | 
                
                 | 
                class ScalarImage(Image):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    499
                 | 
                                    
                                                     | 
                
                 | 
                    """Image whose pixel values represent scalars.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    500
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    501
                 | 
                                    
                                                     | 
                
                 | 
                    Example:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    502
                 | 
                                    
                                                     | 
                
                 | 
                        >>> import torch  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    503
                 | 
                                    
                                                     | 
                
                 | 
                        >>> import torchio as tio  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    504
                 | 
                                    
                                                     | 
                
                 | 
                        >>> # Loading from a file  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    505
                 | 
                                    
                                                     | 
                
                 | 
                        >>> t1_image = tio.ScalarImage('t1.nii.gz') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    506
                 | 
                                    
                                                     | 
                
                 | 
                        >>> dmri = tio.ScalarImage(tensor=torch.rand(32, 128, 128, 88))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    507
                 | 
                                    
                                                     | 
                
                 | 
                        >>> image = tio.ScalarImage('safe_image.nrrd', check_nans=False) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    508
                 | 
                                    
                                                     | 
                
                 | 
                        >>> data, affine = image.data, image.affine  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    509
                 | 
                                    
                                                     | 
                
                 | 
                        >>> affine.shape  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    510
                 | 
                                    
                                                     | 
                
                 | 
                        (4, 4)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    511
                 | 
                                    
                                                     | 
                
                 | 
                        >>> image.data is image[tio.DATA]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    512
                 | 
                                    
                                                     | 
                
                 | 
                        True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    513
                 | 
                                    
                                                     | 
                
                 | 
                        >>> image.data is image.tensor  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    514
                 | 
                                    
                                                     | 
                
                 | 
                        True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    515
                 | 
                                    
                                                     | 
                
                 | 
                        >>> type(image.data)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    516
                 | 
                                    
                                                     | 
                
                 | 
                        torch.Tensor  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    517
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    518
                 | 
                                    
                                                     | 
                
                 | 
                    See :class:`~torchio.Image` for more information.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    519
                 | 
                                    
                                                     | 
                
                 | 
                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    520
                 | 
                                    
                                                     | 
                
                 | 
                    def __init__(self, *args, **kwargs):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    521
                 | 
                                    
                                                     | 
                
                 | 
                        if 'type' in kwargs and kwargs['type'] != INTENSITY:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    522
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError('Type of ScalarImage is always torchio.INTENSITY') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    523
                 | 
                                    
                                                     | 
                
                 | 
                        kwargs.update({'type': INTENSITY}) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    524
                 | 
                                    
                                                     | 
                
                 | 
                        super().__init__(*args, **kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    525
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    526
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    527
                 | 
                                    
                                                     | 
                
                 | 
                class LabelMap(Image):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    528
                 | 
                                    
                                                     | 
                
                 | 
                    """Image whose pixel values represent categorical labels.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    529
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    530
                 | 
                                    
                                                     | 
                
                 | 
                    Intensity transforms are not applied to these images.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    531
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    532
                 | 
                                    
                                                     | 
                
                 | 
                    Example:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    533
                 | 
                                    
                                                     | 
                
                 | 
                        >>> import torch  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    534
                 | 
                                    
                                                     | 
                
                 | 
                        >>> import torchio as tio  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    535
                 | 
                                    
                                                     | 
                
                 | 
                        >>> labels = tio.LabelMap(tensor=torch.rand(1, 128, 128, 68) > 0.5)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    536
                 | 
                                    
                                                     | 
                
                 | 
                        >>> labels = tio.LabelMap('t1_seg.nii.gz')  # loading from a file | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    537
                 | 
                                    
                                                     | 
                
                 | 
                        >>> tpm = tio.LabelMap(                     # loading from files  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    538
                 | 
                                    
                                                     | 
                
                 | 
                        ...     'gray_matter.nii.gz',  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    539
                 | 
                                    
                                                     | 
                
                 | 
                        ...     'white_matter.nii.gz',  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    540
                 | 
                                    
                                                     | 
                
                 | 
                        ...     'csf.nii.gz',  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    541
                 | 
                                    
                                                     | 
                
                 | 
                        ... )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    542
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    543
                 | 
                                    
                                                     | 
                
                 | 
                    See :class:`~torchio.Image` for more information.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    544
                 | 
                                    
                                                     | 
                
                 | 
                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    545
                 | 
                                    
                                                     | 
                
                 | 
                    def __init__(self, *args, **kwargs):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    546
                 | 
                                    
                                                     | 
                
                 | 
                        if 'type' in kwargs and kwargs['type'] != LABEL:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    547
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError('Type of LabelMap is always torchio.LABEL') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    548
                 | 
                                    
                                                     | 
                
                 | 
                        kwargs.update({'type': LABEL}) | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    549
                 | 
                                    
                                                     | 
                
                 | 
                        super().__init__(*args, **kwargs)  | 
            
            
                                                        
            
                                    
            
            
                | 
                    550
                 | 
                                    
                                                     | 
                
                 | 
                 |