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                import copy  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    2
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                import numbers  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    3
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                import warnings  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    4
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                from typing import Union, Tuple  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    5
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                from abc import ABC, abstractmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    6
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                from contextlib import contextmanager  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    7
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                    8
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                import torch  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    9
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                import numpy as np  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    10
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                import SimpleITK as sitk  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    12
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                from ..utils import to_tuple  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    13
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                from ..data.subject import Subject  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    14
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                from ..data.io import nib_to_sitk, sitk_to_nib  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    15
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                from ..data.image import LabelMap  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    16
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                from ..typing import TypeData, TypeNumber, TypeKeys, TypeCallable, TypeTripletInt  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    17
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                from .interpolation import Interpolation, get_sitk_interpolator  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    18
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                from .data_parser import DataParser, TypeTransformInput  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                TypeSixBounds = Tuple[int, int, int, int, int, int]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    21
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                TypeBounds = Union[  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    int,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    23
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                    TypeTripletInt,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    24
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                    TypeSixBounds,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    25
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                ]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                TypeMaskingMethod = Union[str, TypeCallable, TypeBounds, None]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                class Transform(ABC):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    """Abstract class for all TorchIO transforms.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    All subclasses must overwrite  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    33
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                    :meth:`Transform.apply_transform`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    34
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                    which takes data, applies some transformation and returns the result.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    The input can be an instance of  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    37
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                    :class:`torchio.Subject`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    38
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                    :class:`torchio.Image`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    39
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                    :class:`numpy.ndarray`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    40
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                    :class:`torch.Tensor`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    41
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                    :class:`SimpleITK.Image`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    42
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                    or :class:`dict`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    43
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                    Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    45
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                        p: Probability that this transform will be applied.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    46
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                        copy: Make a shallow copy of the input before applying the transform.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    47
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                        include: Sequence of strings with the names of the only images to which  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    48
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                            the transform will be applied.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    49
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                            Mandatory if the input is a :class:`dict`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    50
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                        exclude: Sequence of strings with the names of the images to which the  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    51
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                            the transform will not be applied, apart from the ones that are  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    52
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                            excluded because of the transform type.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    53
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                            For example, if a subject includes an MRI, a CT and a label map, and  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    54
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                            the CT is added to the list of exclusions of an intensity transform  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    55
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                            such as :class:`~torchio.transforms.RandomBlur`,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    56
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                            the transform will be only applied to the MRI, as the label map is  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    57
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                            excluded by default by spatial transforms.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    58
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    59
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                    def __init__(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    60
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                            self,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    61
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                            p: float = 1,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    62
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                            copy: bool = True,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    63
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                            include: TypeKeys = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    64
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                            exclude: TypeKeys = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    65
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                            keys: TypeKeys = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    66
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                            ):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    67
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                        self.probability = self.parse_probability(p)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    68
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                        self.copy = copy  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    69
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                        if keys is not None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    70
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                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    71
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                                'The "keys" argument is deprecated and will be removed in the'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    72
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                                ' future. Use "include" instead.'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    73
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                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    74
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                            warnings.warn(message, DeprecationWarning)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    75
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                            include = keys  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    76
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                        self.include, self.exclude = self.parse_include_and_exclude(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    77
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                            include, exclude)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    78
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                    79
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                    def __call__(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    80
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                            self,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    81
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                            data: TypeTransformInput,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    82
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                            ) -> TypeTransformInput:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    83
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                        """Transform data and return a result of the same type.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    84
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                    85
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                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    86
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                            data: Instance of 1) :class:`~torchio.Subject`, 4D  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    87
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                                :class:`torch.Tensor` or :class:`numpy.ndarray` with dimensions  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    88
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                                :math:`(C, W, H, D)`, where :math:`C` is the number of channels  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    89
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                                and :math:`W, H, D` are the spatial dimensions. If the input is  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    90
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                                a tensor, the affine matrix will be set to identity. Other  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    91
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                                valid input types are a SimpleITK image, a  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    92
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                                :class:`torchio.Image`, a NiBabel Nifti1 image or a  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    93
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                                :class:`dict`. The output type is the same as the input type.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    94
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                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    95
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                        if torch.rand(1).item() > self.probability:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    96
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                            return data  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    97
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                        data_parser = DataParser(data, keys=self.include)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    98
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                        subject = data_parser.get_subject()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    99
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                        if self.copy:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    100
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                            subject = copy.copy(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    101
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                        with np.errstate(all='raise'):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    102
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                            transformed = self.apply_transform(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    103
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                        self.add_transform_to_subject_history(transformed)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    104
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                        for image in transformed.get_images(intensity_only=False):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    105
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                            ndim = image.data.ndim  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    106
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                            assert ndim == 4, f'Output of {self.name} is {ndim}D' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    107
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                    108
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                        output = data_parser.get_output(transformed)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    109
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                        return output  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    110
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                    111
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                    def __repr__(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    112
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                        if hasattr(self, 'args_names'):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    113
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                            names = self.args_names  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    114
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                            args_strings = [f'{arg}={getattr(self, arg)}' for arg in names] | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    115
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                            if hasattr(self, 'invert_transform') and self.invert_transform:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    116
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                                args_strings.append('invert=True') | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    117
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                            args_string = ', '.join(args_strings)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    118
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                            return f'{self.name}({args_string})' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    119
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                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    120
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                            return super().__repr__()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    121
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                    122
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                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    123
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                    def name(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    124
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                        return self.__class__.__name__  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    125
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                    126
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                    @abstractmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    127
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                    def apply_transform(self, subject: Subject):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    128
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                        raise NotImplementedError  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    129
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                    130
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                    def add_transform_to_subject_history(self, subject):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    131
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                        from .augmentation import RandomTransform  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    132
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                                                     | 
                
                 | 
                        from . import Compose, OneOf, CropOrPad  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    133
                 | 
                                    
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                        from .preprocessing.label import SequentialLabels  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    134
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                        call_others = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    135
                 | 
                                    
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                            RandomTransform,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    136
                 | 
                                    
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                 | 
                            Compose,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    137
                 | 
                                    
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                            OneOf,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    138
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                            CropOrPad,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    139
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                            SequentialLabels,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    140
                 | 
                                    
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                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    141
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                        if not isinstance(self, call_others):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    142
                 | 
                                    
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                            subject.add_transform(self, self._get_reproducing_arguments())  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    143
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    144
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                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    145
                 | 
                                    
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                    def to_range(n, around):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    146
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                        if around is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    147
                 | 
                                    
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                            return 0, n  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    148
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                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    149
                 | 
                                    
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                            return around - n, around + n  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    150
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    151
                 | 
                                    
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                    def parse_params(self, params, around, name, make_ranges=True, **kwargs):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    152
                 | 
                                    
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                        params = to_tuple(params)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    153
                 | 
                                    
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                        if len(params) == 1 or (len(params) == 2 and make_ranges):  # d or (a, b)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    154
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                            params *= 3  # (d, d, d) or (a, b, a, b, a, b)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    155
                 | 
                                    
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                 | 
                        if len(params) == 3 and make_ranges:  # (a, b, c)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    156
                 | 
                                    
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                 | 
                            items = [self.to_range(n, around) for n in params]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    157
                 | 
                                    
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                 | 
                            # (-a, a, -b, b, -c, c) or (1-a, 1+a, 1-b, 1+b, 1-c, 1+c)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    158
                 | 
                                    
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                 | 
                            params = [n for prange in items for n in prange]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    159
                 | 
                                    
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                 | 
                        if make_ranges:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    160
                 | 
                                    
                                                     | 
                
                 | 
                            if len(params) != 6:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    161
                 | 
                                    
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                                message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    162
                 | 
                                    
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                 | 
                                    f'If "{name}" is a sequence, it must have length 2, 3 or 6,' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    163
                 | 
                                    
                                                     | 
                
                 | 
                                    f' not {len(params)}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    164
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    165
                 | 
                                    
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                 | 
                                raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    166
                 | 
                                    
                                                     | 
                
                 | 
                            for param_range in zip(params[::2], params[1::2]):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    167
                 | 
                                    
                                                     | 
                
                 | 
                                self._parse_range(param_range, name, **kwargs)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    168
                 | 
                                    
                                                     | 
                
                 | 
                        return tuple(params)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    169
                 | 
                                    
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                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    170
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    171
                 | 
                                    
                                                     | 
                
                 | 
                    def _parse_range(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    172
                 | 
                                    
                                                     | 
                
                 | 
                            nums_range: Union[TypeNumber, Tuple[TypeNumber, TypeNumber]],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    173
                 | 
                                    
                                                     | 
                
                 | 
                            name: str,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    174
                 | 
                                    
                                                     | 
                
                 | 
                            min_constraint: TypeNumber = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    175
                 | 
                                    
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                 | 
                            max_constraint: TypeNumber = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    176
                 | 
                                    
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                 | 
                            type_constraint: type = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    177
                 | 
                                    
                                                     | 
                
                 | 
                            ) -> Tuple[TypeNumber, TypeNumber]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    178
                 | 
                                    
                                                     | 
                
                 | 
                        r"""Adapted from :class:`torchvision.transforms.RandomRotation`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    179
                 | 
                                    
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                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    180
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    181
                 | 
                                    
                                                     | 
                
                 | 
                            nums_range: Tuple of two numbers :math:`(n_{min}, n_{max})`, | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    182
                 | 
                                    
                                                     | 
                
                 | 
                                where :math:`n_{min} \leq n_{max}`. | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    183
                 | 
                                    
                                                     | 
                
                 | 
                                If a single positive number :math:`n` is provided,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    184
                 | 
                                    
                                                     | 
                
                 | 
                                :math:`n_{min} = -n` and :math:`n_{max} = n`. | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    185
                 | 
                                    
                                                     | 
                
                 | 
                            name: Name of the parameter, so that an informative error message  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    186
                 | 
                                    
                                                     | 
                
                 | 
                                can be printed.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    187
                 | 
                                    
                                                     | 
                
                 | 
                            min_constraint: Minimal value that :math:`n_{min}` can take, | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    188
                 | 
                                    
                                                     | 
                
                 | 
                                default is None, i.e. there is no minimal value.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    189
                 | 
                                    
                                                     | 
                
                 | 
                            max_constraint: Maximal value that :math:`n_{max}` can take, | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    190
                 | 
                                    
                                                     | 
                
                 | 
                                default is None, i.e. there is no maximal value.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    191
                 | 
                                    
                                                     | 
                
                 | 
                            type_constraint: Precise type that :math:`n_{max}` and | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    192
                 | 
                                    
                                                     | 
                
                 | 
                                :math:`n_{min}` must take. | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    193
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    194
                 | 
                                    
                                                     | 
                
                 | 
                        Returns:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    195
                 | 
                                    
                                                     | 
                
                 | 
                            A tuple of two numbers :math:`(n_{min}, n_{max})`. | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    196
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    197
                 | 
                                    
                                                     | 
                
                 | 
                        Raises:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    198
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :attr:`nums_range` is negative  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    199
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :math:`n_{max}` or :math:`n_{min}` is not a number | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    200
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :math:`n_{max} \lt n_{min}` | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    201
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :attr:`min_constraint` is not None and  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    202
                 | 
                                    
                                                     | 
                
                 | 
                                :math:`n_{min}` is smaller than :attr:`min_constraint` | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    203
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :attr:`max_constraint` is not None and  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    204
                 | 
                                    
                                                     | 
                
                 | 
                                :math:`n_{max}` is greater than :attr:`max_constraint` | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    205
                 | 
                                    
                                                     | 
                
                 | 
                            ValueError: if :attr:`type_constraint` is not None and  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    206
                 | 
                                    
                                                     | 
                
                 | 
                                :math:`n_{max}` and :math:`n_{max}` are not of type | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    207
                 | 
                                    
                                                     | 
                
                 | 
                                :attr:`type_constraint`.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    208
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    209
                 | 
                                    
                                                     | 
                
                 | 
                        if isinstance(nums_range, numbers.Number):  # single number given  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    210
                 | 
                                    
                                                     | 
                
                 | 
                            if nums_range < 0:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    211
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    212
                 | 
                                    
                                                     | 
                
                 | 
                                    f'If {name} is a single number,' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    213
                 | 
                                    
                                                     | 
                
                 | 
                                    f' it must be positive, not {nums_range}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    214
                 | 
                                    
                                                     | 
                
                 | 
                            if min_constraint is not None and nums_range < min_constraint:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    215
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    216
                 | 
                                    
                                                     | 
                
                 | 
                                    f'If {name} is a single number, it must be greater' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    217
                 | 
                                    
                                                     | 
                
                 | 
                                    f' than {min_constraint}, not {nums_range}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    218
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    219
                 | 
                                    
                                                     | 
                
                 | 
                            if max_constraint is not None and nums_range > max_constraint:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    220
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    221
                 | 
                                    
                                                     | 
                
                 | 
                                    f'If {name} is a single number, it must be smaller' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    222
                 | 
                                    
                                                     | 
                
                 | 
                                    f' than {max_constraint}, not {nums_range}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    223
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    224
                 | 
                                    
                                                     | 
                
                 | 
                            if type_constraint is not None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    225
                 | 
                                    
                                                     | 
                
                 | 
                                if not isinstance(nums_range, type_constraint):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    226
                 | 
                                    
                                                     | 
                
                 | 
                                    raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    227
                 | 
                                    
                                                     | 
                
                 | 
                                        f'If {name} is a single number, it must be of' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    228
                 | 
                                    
                                                     | 
                
                 | 
                                        f' type {type_constraint}, not {nums_range}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    229
                 | 
                                    
                                                     | 
                
                 | 
                                    )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    230
                 | 
                                    
                                                     | 
                
                 | 
                            min_range = -nums_range if min_constraint is None else nums_range  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    231
                 | 
                                    
                                                     | 
                
                 | 
                            return (min_range, nums_range)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    232
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    233
                 | 
                                    
                                                     | 
                
                 | 
                        try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    234
                 | 
                                    
                                                     | 
                
                 | 
                            min_value, max_value = nums_range  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    235
                 | 
                                    
                                                     | 
                
                 | 
                        except (TypeError, ValueError):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    236
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    237
                 | 
                                    
                                                     | 
                
                 | 
                                f'If {name} is not a single number, it must be' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    238
                 | 
                                    
                                                     | 
                
                 | 
                                f' a sequence of len 2, not {nums_range}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    239
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    240
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    241
                 | 
                                    
                                                     | 
                
                 | 
                        min_is_number = isinstance(min_value, numbers.Number)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    242
                 | 
                                    
                                                     | 
                
                 | 
                        max_is_number = isinstance(max_value, numbers.Number)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    243
                 | 
                                    
                                                     | 
                
                 | 
                        if not min_is_number or not max_is_number:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    244
                 | 
                                    
                                                     | 
                
                 | 
                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    245
                 | 
                                    
                                                     | 
                
                 | 
                                f'{name} values must be numbers, not {nums_range}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    246
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    247
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    248
                 | 
                                    
                                                     | 
                
                 | 
                        if min_value > max_value:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    249
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    250
                 | 
                                    
                                                     | 
                
                 | 
                                f'If {name} is a sequence, the second value must be' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    251
                 | 
                                    
                                                     | 
                
                 | 
                                f' equal or greater than the first, but it is {nums_range}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    252
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    253
                 | 
                                    
                                                     | 
                
                 | 
                        if min_constraint is not None and min_value < min_constraint:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    254
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    255
                 | 
                                    
                                                     | 
                
                 | 
                                f'If {name} is a sequence, the first value must be greater' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    256
                 | 
                                    
                                                     | 
                
                 | 
                                f' than {min_constraint}, but it is {min_value}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    257
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    258
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    259
                 | 
                                    
                                                     | 
                
                 | 
                        if max_constraint is not None and max_value > max_constraint:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    260
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    261
                 | 
                                    
                                                     | 
                
                 | 
                                f'If {name} is a sequence, the second value must be smaller' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    262
                 | 
                                    
                                                     | 
                
                 | 
                                f' than {max_constraint}, but it is {max_value}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    263
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    264
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    265
                 | 
                                    
                                                     | 
                
                 | 
                        if type_constraint is not None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    266
                 | 
                                    
                                                     | 
                
                 | 
                            min_type_ok = isinstance(min_value, type_constraint)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    267
                 | 
                                    
                                                     | 
                
                 | 
                            max_type_ok = isinstance(max_value, type_constraint)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    268
                 | 
                                    
                                                     | 
                
                 | 
                            if not min_type_ok or not max_type_ok:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    269
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    270
                 | 
                                    
                                                     | 
                
                 | 
                                    f'If "{name}" is a sequence, its values must be of' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    271
                 | 
                                    
                                                     | 
                
                 | 
                                    f' type "{type_constraint}", not "{type(nums_range)}"' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    272
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    273
                 | 
                                    
                                                     | 
                
                 | 
                        return nums_range  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    274
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    275
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    276
                 | 
                                    
                                                     | 
                
                 | 
                    def parse_interpolation(interpolation: str) -> str:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    277
                 | 
                                    
                                                     | 
                
                 | 
                        if not isinstance(interpolation, str):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    278
                 | 
                                    
                                                     | 
                
                 | 
                            itype = type(interpolation)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    279
                 | 
                                    
                                                     | 
                
                 | 
                            raise TypeError(f'Interpolation must be a string, not {itype}') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    280
                 | 
                                    
                                                     | 
                
                 | 
                        interpolation = interpolation.lower()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    281
                 | 
                                    
                                                     | 
                
                 | 
                        is_string = isinstance(interpolation, str)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    282
                 | 
                                    
                                                     | 
                
                 | 
                        supported_values = [key.name.lower() for key in Interpolation]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    283
                 | 
                                    
                                                     | 
                
                 | 
                        is_supported = interpolation.lower() in supported_values  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    284
                 | 
                                    
                                                     | 
                
                 | 
                        if is_string and is_supported:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    285
                 | 
                                    
                                                     | 
                
                 | 
                            return interpolation  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    286
                 | 
                                    
                                                     | 
                
                 | 
                        message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    287
                 | 
                                    
                                                     | 
                
                 | 
                            f'Interpolation "{interpolation}" of type {type(interpolation)}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    288
                 | 
                                    
                                                     | 
                
                 | 
                            f' must be a string among the supported values: {supported_values}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    289
                 | 
                                    
                                                     | 
                
                 | 
                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    290
                 | 
                                    
                                                     | 
                
                 | 
                        raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    291
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    292
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    293
                 | 
                                    
                                                     | 
                
                 | 
                    def parse_probability(probability: float) -> float:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    294
                 | 
                                    
                                                     | 
                
                 | 
                        is_number = isinstance(probability, numbers.Number)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    295
                 | 
                                    
                                                     | 
                
                 | 
                        if not (is_number and 0 <= probability <= 1):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    296
                 | 
                                    
                                                     | 
                
                 | 
                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    297
                 | 
                                    
                                                     | 
                
                 | 
                                'Probability must be a number in [0, 1],'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    298
                 | 
                                    
                                                     | 
                
                 | 
                                f' not {probability}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    299
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    300
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    301
                 | 
                                    
                                                     | 
                
                 | 
                        return probability  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    302
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    303
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    304
                 | 
                                    
                                                     | 
                
                 | 
                    def parse_include_and_exclude(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    305
                 | 
                                    
                                                     | 
                
                 | 
                            include: TypeKeys = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    306
                 | 
                                    
                                                     | 
                
                 | 
                            exclude: TypeKeys = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    307
                 | 
                                    
                                                     | 
                
                 | 
                            ) -> Tuple[TypeKeys, TypeKeys]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    308
                 | 
                                    
                                                     | 
                
                 | 
                        if include is not None and exclude is not None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    309
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError('Include and exclude cannot both be specified') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    310
                 | 
                                    
                                                     | 
                
                 | 
                        return include, exclude  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    311
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    312
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    313
                 | 
                                    
                                                     | 
                
                 | 
                    def nib_to_sitk(data: TypeData, affine: TypeData) -> sitk.Image:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    314
                 | 
                                    
                                                     | 
                
                 | 
                        return nib_to_sitk(data, affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    315
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    316
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    317
                 | 
                                    
                                                     | 
                
                 | 
                    def sitk_to_nib(image: sitk.Image) -> Tuple[torch.Tensor, np.ndarray]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    318
                 | 
                                    
                                                     | 
                
                 | 
                        return sitk_to_nib(image)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    319
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    320
                 | 
                                    
                                                     | 
                
                 | 
                    def _get_reproducing_arguments(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    321
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    322
                 | 
                                    
                                                     | 
                
                 | 
                        Return a dictionary with the arguments that would be necessary to  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    323
                 | 
                                    
                                                     | 
                
                 | 
                        reproduce the transform exactly.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    324
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    325
                 | 
                                    
                                                     | 
                
                 | 
                        reproducing_arguments = {'include': self.include, 'exclude': self.exclude, 'copy': self.copy} | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    326
                 | 
                                    
                                                     | 
                
                 | 
                        reproducing_arguments.update({name: getattr(self, name) for name in self.args_names}) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    327
                 | 
                                    
                                                     | 
                
                 | 
                        return reproducing_arguments  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    328
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    329
                 | 
                                    
                                                     | 
                
                 | 
                    def is_invertible(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    330
                 | 
                                    
                                                     | 
                
                 | 
                        return hasattr(self, 'invert_transform')  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    331
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    332
                 | 
                                    
                                                     | 
                
                 | 
                    def inverse(self):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    333
                 | 
                                    
                                                     | 
                
                 | 
                        if not self.is_invertible():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    334
                 | 
                                    
                                                     | 
                
                 | 
                            raise RuntimeError(f'{self.name} is not invertible') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    335
                 | 
                                    
                                                     | 
                
                 | 
                        new = copy.deepcopy(self)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    336
                 | 
                                    
                                                     | 
                
                 | 
                        new.invert_transform = not self.invert_transform  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    337
                 | 
                                    
                                                     | 
                
                 | 
                        return new  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    338
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    339
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    340
                 | 
                                    
                                                     | 
                
                 | 
                    @contextmanager  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    341
                 | 
                                    
                                                     | 
                
                 | 
                    def _use_seed(seed):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    342
                 | 
                                    
                                                     | 
                
                 | 
                        """Perform an operation using a specific seed for the PyTorch RNG"""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    343
                 | 
                                    
                                                     | 
                
                 | 
                        torch_rng_state = torch.random.get_rng_state()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    344
                 | 
                                    
                                                     | 
                
                 | 
                        torch.manual_seed(seed)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    345
                 | 
                                    
                                                     | 
                
                 | 
                        yield  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    346
                 | 
                                    
                                                     | 
                
                 | 
                        torch.random.set_rng_state(torch_rng_state)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    347
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    348
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    349
                 | 
                                    
                                                     | 
                
                 | 
                    def get_sitk_interpolator(interpolation: str) -> int:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    350
                 | 
                                    
                                                     | 
                
                 | 
                        return get_sitk_interpolator(interpolation)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    351
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    352
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    353
                 | 
                                    
                                                     | 
                
                 | 
                    def parse_bounds(bounds_parameters: TypeBounds) -> TypeSixBounds:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    354
                 | 
                                    
                                                     | 
                
                 | 
                        try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    355
                 | 
                                    
                                                     | 
                
                 | 
                            bounds_parameters = tuple(bounds_parameters)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    356
                 | 
                                    
                                                     | 
                
                 | 
                        except TypeError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    357
                 | 
                                    
                                                     | 
                
                 | 
                            bounds_parameters = (bounds_parameters,)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    358
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    359
                 | 
                                    
                                                     | 
                
                 | 
                        # Check that numbers are integers  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    360
                 | 
                                    
                                                     | 
                
                 | 
                        for number in bounds_parameters:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    361
                 | 
                                    
                                                     | 
                
                 | 
                            if not isinstance(number, (int, np.integer)) or number < 0:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    362
                 | 
                                    
                                                     | 
                
                 | 
                                message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    363
                 | 
                                    
                                                     | 
                
                 | 
                                    'Bounds values must be integers greater or equal to zero,'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    364
                 | 
                                    
                                                     | 
                
                 | 
                                    f' not "{bounds_parameters}" of type {type(number)}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    365
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    366
                 | 
                                    
                                                     | 
                
                 | 
                                raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    367
                 | 
                                    
                                                     | 
                
                 | 
                        bounds_parameters = tuple(int(n) for n in bounds_parameters)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    368
                 | 
                                    
                                                     | 
                
                 | 
                        bounds_parameters_length = len(bounds_parameters)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    369
                 | 
                                    
                                                     | 
                
                 | 
                        if bounds_parameters_length == 6:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    370
                 | 
                                    
                                                     | 
                
                 | 
                            return bounds_parameters  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    371
                 | 
                                    
                                                     | 
                
                 | 
                        if bounds_parameters_length == 1:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    372
                 | 
                                    
                                                     | 
                
                 | 
                            return 6 * bounds_parameters  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    373
                 | 
                                    
                                                     | 
                
                 | 
                        if bounds_parameters_length == 3:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    374
                 | 
                                    
                                                     | 
                
                 | 
                            return tuple(np.repeat(bounds_parameters, 2).tolist())  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    375
                 | 
                                    
                                                     | 
                
                 | 
                        message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    376
                 | 
                                    
                                                     | 
                
                 | 
                            'Bounds parameter must be an integer or a tuple of'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    377
                 | 
                                    
                                                     | 
                
                 | 
                            f' 3 or 6 integers, not {bounds_parameters}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    378
                 | 
                                    
                                                     | 
                
                 | 
                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    379
                 | 
                                    
                                                     | 
                
                 | 
                        raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    380
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    381
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    382
                 | 
                                    
                                                     | 
                
                 | 
                    def ones(tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    383
                 | 
                                    
                                                     | 
                
                 | 
                        return torch.ones_like(tensor, dtype=torch.bool)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    384
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    385
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    386
                 | 
                                    
                                                     | 
                
                 | 
                    def mean(tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    387
                 | 
                                    
                                                     | 
                
                 | 
                        mask = tensor > tensor.mean()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    388
                 | 
                                    
                                                     | 
                
                 | 
                        return mask  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    389
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    390
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    391
                 | 
                                    
                                                     | 
                
                 | 
                    def get_mask(masking_method: TypeMaskingMethod, subject: Subject, tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    392
                 | 
                                    
                                                     | 
                
                 | 
                        if masking_method is None:  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    393
                 | 
                                    
                                                     | 
                
                 | 
                            return Transform.ones(tensor)  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    394
                 | 
                                    
                                                     | 
                
                 | 
                        elif callable(masking_method):  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    395
                 | 
                                    
                                                     | 
                
                 | 
                            return masking_method(tensor)  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    396
                 | 
                                    
                                                     | 
                
                 | 
                        elif type(masking_method) is str:  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    397
                 | 
                                    
                                                     | 
                
                 | 
                            if masking_method in subject and isinstance(subject[masking_method], LabelMap):  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    398
                 | 
                                    
                                                     | 
                
                 | 
                                return subject[masking_method].data.bool()  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    399
                 | 
                                    
                                                     | 
                
                 | 
                            if masking_method.title() in ('Left', 'Right', 'Anterior', 'Posterior', 'Inferior', 'Superior'): | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    400
                 | 
                                    
                                                     | 
                
                 | 
                                return Transform.get_mask_from_anatomical_label(masking_method.title(), tensor)  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    401
                 | 
                                    
                                                     | 
                
                 | 
                        elif type(masking_method) in (tuple, list, int):  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    402
                 | 
                                    
                                                     | 
                
                 | 
                            return Transform.get_mask_from_bounds(masking_method, tensor)  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    403
                 | 
                                    
                                                     | 
                
                 | 
                        message = (  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    404
                 | 
                                    
                                                     | 
                
                 | 
                            'Masking method parameter must be a function, a label map name,'  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    405
                 | 
                                    
                                                     | 
                
                 | 
                            " an anatomical label: ('Left', 'Right', 'Anterior', 'Posterior', 'Inferior', 'Superior')," | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    406
                 | 
                                    
                                                     | 
                
                 | 
                            ' or a bounds parameter: (an int, tuple of 3 ints, or tuple of 6 ints)'  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    407
                 | 
                                    
                                                     | 
                
                 | 
                            f' not {masking_method} of type {type(masking_method)}' | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    408
                 | 
                                    
                                                     | 
                
                 | 
                        )  | 
            
            
                                                                        
                            
            
                                    
            
            
                | 
                    409
                 | 
                                    
                                                     | 
                
                 | 
                        raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    410
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    411
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    412
                 | 
                                    
                                                     | 
                
                 | 
                    def get_mask_from_anatomical_label(anatomical_label: str, tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    413
                 | 
                                    
                                                     | 
                
                 | 
                        anatomical_label = anatomical_label.title()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    414
                 | 
                                    
                                                     | 
                
                 | 
                        if anatomical_label.title() not in ('Left', 'Right', 'Anterior', 'Posterior', 'Inferior', 'Superior'): | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    415
                 | 
                                    
                                                     | 
                
                 | 
                            message = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    416
                 | 
                                    
                                                     | 
                
                 | 
                                "Anatomical label must be one of ('Left', 'Right', 'Anterior', 'Posterior', 'Inferior', 'Superior')" | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    417
                 | 
                                    
                                                     | 
                
                 | 
                                f' not {anatomical_label}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    418
                 | 
                                    
                                                     | 
                
                 | 
                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    419
                 | 
                                    
                                                     | 
                
                 | 
                            raise ValueError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    420
                 | 
                                    
                                                     | 
                
                 | 
                        mask = torch.zeros_like(tensor, dtype=torch.bool)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    421
                 | 
                                    
                                                     | 
                
                 | 
                        _, width, height, depth = tensor.shape  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    422
                 | 
                                    
                                                     | 
                
                 | 
                        if anatomical_label == 'Right':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    423
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, width // 2:] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    424
                 | 
                                    
                                                     | 
                
                 | 
                        elif anatomical_label == 'Left':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    425
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, :width // 2] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    426
                 | 
                                    
                                                     | 
                
                 | 
                        elif anatomical_label == 'Anterior':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    427
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, :, height // 2:] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    428
                 | 
                                    
                                                     | 
                
                 | 
                        elif anatomical_label == 'Posterior':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    429
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, :, :height // 2] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    430
                 | 
                                    
                                                     | 
                
                 | 
                        elif anatomical_label == 'Superior':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    431
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, :, :, depth // 2:] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    432
                 | 
                                    
                                                     | 
                
                 | 
                        elif anatomical_label == 'Inferior':  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    433
                 | 
                                    
                                                     | 
                
                 | 
                            mask[:, :, :, :depth // 2] = True  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    434
                 | 
                                    
                                                     | 
                
                 | 
                        return mask  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    435
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    436
                 | 
                                    
                                                     | 
                
                 | 
                    @staticmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    437
                 | 
                                    
                                                     | 
                
                 | 
                    def get_mask_from_bounds(bounds_parameters: TypeBounds, tensor: torch.Tensor) -> torch.Tensor:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    438
                 | 
                                    
                                                     | 
                
                 | 
                        bounds_parameters = Transform.parse_bounds(bounds_parameters)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    439
                 | 
                                    
                                                     | 
                
                 | 
                        low = bounds_parameters[::2]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    440
                 | 
                                    
                                                     | 
                
                 | 
                        high = bounds_parameters[1::2]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    441
                 | 
                                    
                                                     | 
                
                 | 
                        i0, j0, k0 = low  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    442
                 | 
                                    
                                                     | 
                
                 | 
                        i1, j1, k1 = np.array(tensor.shape[1:]) - high  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    443
                 | 
                                    
                                                     | 
                
                 | 
                        mask = torch.zeros_like(tensor, dtype=torch.bool)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    444
                 | 
                                    
                                                     | 
                
                 | 
                        mask[:, i0:i1, j0:j1, k0:k1] = True  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    445
                 | 
                                    
                                                     | 
                
                 | 
                        return mask  | 
            
            
                                                        
            
                                    
            
            
                | 
                    446
                 | 
                                    
                                                     | 
                
                 | 
                 |