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                import ast  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    2
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                import gzip  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    3
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                import shutil  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    4
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                import tempfile  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    5
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                from pathlib import Path  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    6
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                from typing import Union, Iterable, Tuple, Any, Optional, List, Sequence  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from torch.utils.data._utils.collate import default_collate  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                import numpy as np  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                import nibabel as nib  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                import SimpleITK as sitk  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    12
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                from tqdm import trange  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                from .typing import TypeNumber, TypePath  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                def to_tuple(  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        value: Union[TypeNumber, Iterable[TypeNumber]],  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        length: int = 1,  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        ) -> Tuple[TypeNumber, ...]:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    21
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                    """  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    22
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                    to_tuple(1, length=1) -> (1,)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    23
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                    to_tuple(1, length=3) -> (1, 1, 1)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    If value is an iterable, n is ignored and tuple(value) is returned  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    to_tuple((1,), length=1) -> (1,)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    to_tuple((1, 2), length=1) -> (1, 2)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    to_tuple([1, 2], length=3) -> (1, 2)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    29
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                    """  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    30
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                    try:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    31
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                        iter(value)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                        value = tuple(value)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    except TypeError:  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    34
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                        value = length * (value,)  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    return value  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                def get_stem(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    39
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                        path: Union[TypePath, List[TypePath]]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    40
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                        ) -> Union[str, List[str]]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    41
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    42
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                    '/home/user/image.nii.gz' -> 'image'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    43
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                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    44
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                    def _get_stem(path_string):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    45
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                        return Path(path_string).name.split('.')[0] | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    46
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                    if isinstance(path, (str, Path)):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    47
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                        return _get_stem(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    48
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                    return [_get_stem(p) for p in path]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                def create_dummy_dataset(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    52
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                        num_images: int,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    53
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                        size_range: Tuple[int, int],  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    54
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                        directory: Optional[TypePath] = None,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    55
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                        suffix: str = '.nii.gz',  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    56
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                        force: bool = False,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    57
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                        verbose: bool = False,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    58
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                        ):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    59
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                    from .data import ScalarImage, LabelMap, Subject  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    60
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                    output_dir = tempfile.gettempdir() if directory is None else directory  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    61
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                    output_dir = Path(output_dir)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    62
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                    images_dir = output_dir / 'dummy_images'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    63
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                    labels_dir = output_dir / 'dummy_labels'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    if force:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    66
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                        shutil.rmtree(images_dir)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                        shutil.rmtree(labels_dir)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    subjects: List[Subject] = []  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    if images_dir.is_dir():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    71
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                        for i in trange(num_images):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            image_path = images_dir / f'image_{i}{suffix}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            label_path = labels_dir / f'label_{i}{suffix}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            subject = Subject(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                one_modality=ScalarImage(image_path),  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                                segmentation=LabelMap(label_path),  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                            subjects.append(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    79
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                    else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    80
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                        images_dir.mkdir(exist_ok=True, parents=True)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    81
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                        labels_dir.mkdir(exist_ok=True, parents=True)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    82
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                        if verbose:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    83
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                            print('Creating dummy dataset...')  # noqa: T001 | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    84
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                            iterable = trange(num_images)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    85
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                        else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    86
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                            iterable = range(num_images)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    87
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                        for i in iterable:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    88
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                            shape = np.random.randint(*size_range, size=3)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    89
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                            affine = np.eye(4)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    90
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                            image = np.random.rand(*shape)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    91
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                            label = np.ones_like(image)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    92
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                            label[image < 0.33] = 0  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    93
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                            label[image > 0.66] = 2  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    94
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                            image *= 255  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    95
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                    96
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                            image_path = images_dir / f'image_{i}{suffix}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    97
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                            nii = nib.Nifti1Image(image.astype(np.uint8), affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    98
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                            nii.to_filename(str(image_path))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    99
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                    100
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                            label_path = labels_dir / f'label_{i}{suffix}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    101
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                            nii = nib.Nifti1Image(label.astype(np.uint8), affine)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    102
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                            nii.to_filename(str(label_path))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    103
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                    104
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                            subject = Subject(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    105
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                                one_modality=ScalarImage(image_path),  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    106
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                                segmentation=LabelMap(label_path),  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    107
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                            )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    108
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                            subjects.append(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    109
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                    return subjects  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    110
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                    111
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                    112
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                def apply_transform_to_file(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    113
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                        input_path: TypePath,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    114
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                        transform,  # : Transform seems to create a circular import  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    115
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                        output_path: TypePath,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    116
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                        class_: str = 'ScalarImage',  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    117
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                        verbose: bool = False,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    118
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                        ):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    119
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                    from . import data  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    120
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                    image = getattr(data, class_)(input_path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    121
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                    subject = data.Subject(image=image)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    122
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                    transformed = transform(subject)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    123
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                    transformed.image.save(output_path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    124
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                    if verbose and transformed.history:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    125
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                        print('Applied transform:', transformed.history[0])  # noqa: T001 | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    126
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                    127
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                | 
                    128
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                def guess_type(string: str) -> Any:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    129
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                    # Adapted from  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    130
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                    # https://www.reddit.com/r/learnpython/comments/4599hl/module_to_guess_type_from_a_string/czw3f5s  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    131
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                    string = string.replace(' ', '') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    132
                 | 
                                    
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                    try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    133
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                                                     | 
                
                 | 
                        value = ast.literal_eval(string)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    134
                 | 
                                    
                                                     | 
                
                 | 
                    except ValueError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    135
                 | 
                                    
                                                     | 
                
                 | 
                        result_type = str  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    136
                 | 
                                    
                                                     | 
                
                 | 
                    else:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    137
                 | 
                                    
                                                     | 
                
                 | 
                        result_type = type(value)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    138
                 | 
                                    
                                                     | 
                
                 | 
                    if result_type in (list, tuple):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    139
                 | 
                                    
                                                     | 
                
                 | 
                        string = string[1:-1]  # remove brackets  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    140
                 | 
                                    
                                                     | 
                
                 | 
                        split = string.split(',') | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    141
                 | 
                                    
                                                     | 
                
                 | 
                        list_result = [guess_type(n) for n in split]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    142
                 | 
                                    
                                                     | 
                
                 | 
                        value = tuple(list_result) if result_type is tuple else list_result  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    143
                 | 
                                    
                                                     | 
                
                 | 
                        return value  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    144
                 | 
                                    
                                                     | 
                
                 | 
                    try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    145
                 | 
                                    
                                                     | 
                
                 | 
                        value = result_type(string)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    146
                 | 
                                    
                                                     | 
                
                 | 
                    except TypeError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    147
                 | 
                                    
                                                     | 
                
                 | 
                        value = None  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    148
                 | 
                                    
                                                     | 
                
                 | 
                    return value  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    149
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    150
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    151
                 | 
                                    
                                                     | 
                
                 | 
                def get_torchio_cache_dir():  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    152
                 | 
                                    
                                                     | 
                
                 | 
                    return Path('~/.cache/torchio').expanduser() | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    153
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    154
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    155
                 | 
                                    
                                                     | 
                
                 | 
                def compress(input_path, output_path):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    156
                 | 
                                    
                                                     | 
                
                 | 
                    with open(input_path, 'rb') as f_in:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    157
                 | 
                                    
                                                     | 
                
                 | 
                        with gzip.open(output_path, 'wb') as f_out:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    158
                 | 
                                    
                                                     | 
                
                 | 
                            shutil.copyfileobj(f_in, f_out)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    159
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    160
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    161
                 | 
                                    
                                                     | 
                
                 | 
                def check_sequence(sequence: Sequence, name: str):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    162
                 | 
                                    
                                                     | 
                
                 | 
                    try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    163
                 | 
                                    
                                                     | 
                
                 | 
                        iter(sequence)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    164
                 | 
                                    
                                                     | 
                
                 | 
                    except TypeError:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    165
                 | 
                                    
                                                     | 
                
                 | 
                        message = f'"{name}" must be a sequence, not {type(name)}' | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    166
                 | 
                                    
                                                     | 
                
                 | 
                        raise TypeError(message)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    167
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    168
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    169
                 | 
                                    
                                                     | 
                
                 | 
                def get_major_sitk_version() -> int:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    170
                 | 
                                    
                                                     | 
                
                 | 
                    # This attribute was added in version 2  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    171
                 | 
                                    
                                                     | 
                
                 | 
                    # https://github.com/SimpleITK/SimpleITK/pull/1171  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    172
                 | 
                                    
                                                     | 
                
                 | 
                    version = getattr(sitk, '__version__', None)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    173
                 | 
                                    
                                                     | 
                
                 | 
                    major_version = 1 if version is None else 2  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    174
                 | 
                                    
                                                     | 
                
                 | 
                    return major_version  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    175
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    176
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    177
                 | 
                                    
                                                     | 
                
                 | 
                def history_collate(batch: Sequence, collate_transforms=True):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    178
                 | 
                                    
                                                     | 
                
                 | 
                    attr = 'history' if collate_transforms else 'applied_transforms'  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    179
                 | 
                                    
                                                     | 
                
                 | 
                    # Adapted from  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    180
                 | 
                                    
                                                     | 
                
                 | 
                    # https://github.com/romainVala/torchQC/blob/master/segmentation/collate_functions.py  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    181
                 | 
                                    
                                                     | 
                
                 | 
                    from .data import Subject  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    182
                 | 
                                    
                                                     | 
                
                 | 
                    first_element = batch[0]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    183
                 | 
                                    
                                                     | 
                
                 | 
                    if isinstance(first_element, Subject):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    184
                 | 
                                    
                                                     | 
                
                 | 
                        dictionary = { | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    185
                 | 
                                    
                                                     | 
                
                 | 
                            key: default_collate([d[key] for d in batch])  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    186
                 | 
                                    
                                                     | 
                
                 | 
                            for key in first_element  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    187
                 | 
                                    
                                                     | 
                
                 | 
                        }  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    188
                 | 
                                    
                                                     | 
                
                 | 
                        if hasattr(first_element, attr):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    189
                 | 
                                    
                                                     | 
                
                 | 
                            dictionary.update({attr: [getattr(d, attr) for d in batch]}) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    190
                 | 
                                    
                                                     | 
                
                 | 
                        return dictionary  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    191
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    192
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    193
                 | 
                                    
                                                     | 
                
                 | 
                def get_subclasses(target_class: type) -> List[type]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    194
                 | 
                                    
                                                     | 
                
                 | 
                    subclasses = target_class.__subclasses__()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    195
                 | 
                                    
                                                     | 
                
                 | 
                    subclasses += sum((get_subclasses(cls) for cls in subclasses), [])  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    196
                 | 
                                    
                                                     | 
                
                 | 
                    return subclasses  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    197
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    198
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    199
                 | 
                                    
                                                     | 
                
                 | 
                def get_first_item(data_loader):  | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    200
                 | 
                                    
                                                     | 
                
                 | 
                    return next(iter(data_loader))  | 
            
            
                                                        
            
                                    
            
            
                | 
                    201
                 | 
                                    
                                                     | 
                
                 | 
                 |