| 1 |  |  | import copy | 
            
                                                                                                            
                            
            
                                    
            
            
                | 2 |  |  | import numbers | 
            
                                                                                                            
                            
            
                                    
            
            
                | 3 |  |  | import warnings | 
            
                                                                                                            
                            
            
                                    
            
            
                | 4 |  |  | from typing import Union, Tuple | 
            
                                                                                                            
                            
            
                                    
            
            
                | 5 |  |  | from abc import ABC, abstractmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 6 |  |  | from contextlib import contextmanager | 
            
                                                                                                            
                            
            
                                    
            
            
                | 7 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 8 |  |  | import torch | 
            
                                                                                                            
                            
            
                                    
            
            
                | 9 |  |  | import numpy as np | 
            
                                                                                                            
                            
            
                                    
            
            
                | 10 |  |  | import SimpleITK as sitk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 11 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 12 |  |  | from ..utils import to_tuple | 
            
                                                                                                            
                            
            
                                    
            
            
                | 13 |  |  | from ..data.subject import Subject | 
            
                                                                                                            
                            
            
                                    
            
            
                | 14 |  |  | from ..data.io import nib_to_sitk, sitk_to_nib | 
            
                                                                                                            
                            
            
                                    
            
            
                | 15 |  |  | from ..data.image import LabelMap | 
            
                                                                                                            
                            
            
                                    
            
            
                | 16 |  |  | from ..typing import ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 17 |  |  |     TypeKeys, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 18 |  |  |     TypeData, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 19 |  |  |     TypeNumber, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 20 |  |  |     TypeCallable, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 21 |  |  |     TypeTripletInt, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 22 |  |  | ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 23 |  |  | from .interpolation import Interpolation, get_sitk_interpolator | 
            
                                                                                                            
                            
            
                                    
            
            
                | 24 |  |  | from .data_parser import DataParser, TypeTransformInput | 
            
                                                                                                            
                            
            
                                    
            
            
                | 25 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 26 |  |  | TypeSixBounds = Tuple[int, int, int, int, int, int] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 27 |  |  | TypeBounds = Union[ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 28 |  |  |     int, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 29 |  |  |     TypeTripletInt, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 30 |  |  |     TypeSixBounds, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 31 |  |  | ] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 32 |  |  | TypeMaskingMethod = Union[str, TypeCallable, TypeBounds, None] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 33 |  |  | anat_axes = 'Left', 'Right', 'Anterior', 'Posterior', 'Inferior', 'Superior' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 34 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 35 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 36 |  |  | class Transform(ABC): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 37 |  |  |     """Abstract class for all TorchIO transforms. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 38 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 39 |  |  |     All subclasses must overwrite | 
            
                                                                                                            
                            
            
                                    
            
            
                | 40 |  |  |     :meth:`Transform.apply_transform`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 41 |  |  |     which takes data, applies some transformation and returns the result. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 42 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 43 |  |  |     The input can be an instance of | 
            
                                                                                                            
                            
            
                                    
            
            
                | 44 |  |  |     :class:`torchio.Subject`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 45 |  |  |     :class:`torchio.Image`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 46 |  |  |     :class:`numpy.ndarray`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 47 |  |  |     :class:`torch.Tensor`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 48 |  |  |     :class:`SimpleITK.Image`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 49 |  |  |     or :class:`dict`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 50 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 51 |  |  |     Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 52 |  |  |         p: Probability that this transform will be applied. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 53 |  |  |         copy: Make a shallow copy of the input before applying the transform. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 54 |  |  |         include: Sequence of strings with the names of the only images to which | 
            
                                                                                                            
                            
            
                                    
            
            
                | 55 |  |  |             the transform will be applied. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 56 |  |  |             Mandatory if the input is a :class:`dict`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 57 |  |  |         exclude: Sequence of strings with the names of the images to which the | 
            
                                                                                                            
                            
            
                                    
            
            
                | 58 |  |  |             the transform will not be applied, apart from the ones that are | 
            
                                                                                                            
                            
            
                                    
            
            
                | 59 |  |  |             excluded because of the transform type. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 60 |  |  |             For example, if a subject includes an MRI, a CT and a label map, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 61 |  |  |             and the CT is added to the list of exclusions of an intensity | 
            
                                                                                                            
                            
            
                                    
            
            
                | 62 |  |  |             transform such as :class:`~torchio.transforms.RandomBlur`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 63 |  |  |             the transform will be only applied to the MRI, as the label map is | 
            
                                                                                                            
                            
            
                                    
            
            
                | 64 |  |  |             excluded by default by spatial transforms. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 65 |  |  |     """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 66 |  |  |     def __init__( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 67 |  |  |             self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 68 |  |  |             p: float = 1, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 69 |  |  |             copy: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 70 |  |  |             include: TypeKeys = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 71 |  |  |             exclude: TypeKeys = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 72 |  |  |             keys: TypeKeys = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 73 |  |  |             ): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 74 |  |  |         self.probability = self.parse_probability(p) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 75 |  |  |         self.copy = copy | 
            
                                                                                                            
                            
            
                                    
            
            
                | 76 |  |  |         if keys is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 77 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 78 |  |  |                 'The "keys" argument is deprecated and will be removed in the' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 79 |  |  |                 ' future. Use "include" instead.' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 80 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 81 |  |  |             warnings.warn(message, DeprecationWarning) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 82 |  |  |             include = keys | 
            
                                                                                                            
                            
            
                                    
            
            
                | 83 |  |  |         self.include, self.exclude = self.parse_include_and_exclude( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 84 |  |  |             include, exclude) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 85 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 86 |  |  |     def __call__( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 87 |  |  |             self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 88 |  |  |             data: TypeTransformInput, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 89 |  |  |             ) -> TypeTransformInput: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 90 |  |  |         """Transform data and return a result of the same type. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 91 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 92 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 93 |  |  |             data: Instance of 1) :class:`~torchio.Subject`, 4D | 
            
                                                                                                            
                            
            
                                    
            
            
                | 94 |  |  |                 :class:`torch.Tensor` or :class:`numpy.ndarray` with dimensions | 
            
                                                                                                            
                            
            
                                    
            
            
                | 95 |  |  |                 :math:`(C, W, H, D)`, where :math:`C` is the number of channels | 
            
                                                                                                            
                            
            
                                    
            
            
                | 96 |  |  |                 and :math:`W, H, D` are the spatial dimensions. If the input is | 
            
                                                                                                            
                            
            
                                    
            
            
                | 97 |  |  |                 a tensor, the affine matrix will be set to identity. Other | 
            
                                                                                                            
                            
            
                                    
            
            
                | 98 |  |  |                 valid input types are a SimpleITK image, a | 
            
                                                                                                            
                            
            
                                    
            
            
                | 99 |  |  |                 :class:`torchio.Image`, a NiBabel Nifti1 image or a | 
            
                                                                                                            
                            
            
                                    
            
            
                | 100 |  |  |                 :class:`dict`. The output type is the same as the input type. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 101 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 102 |  |  |         if torch.rand(1).item() > self.probability: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 103 |  |  |             return data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 104 |  |  |         data_parser = DataParser(data, keys=self.include) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 105 |  |  |         subject = data_parser.get_subject() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 106 |  |  |         if self.copy: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 107 |  |  |             subject = copy.copy(subject) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 108 |  |  |         with np.errstate(all='raise'): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 109 |  |  |             transformed = self.apply_transform(subject) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 110 |  |  |         self.add_transform_to_subject_history(transformed) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 111 |  |  |         for image in transformed.get_images(intensity_only=False): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 112 |  |  |             ndim = image.data.ndim | 
            
                                                                                                            
                            
            
                                    
            
            
                | 113 |  |  |             assert ndim == 4, f'Output of {self.name} is {ndim}D' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 114 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 115 |  |  |         output = data_parser.get_output(transformed) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 116 |  |  |         return output | 
            
                                                                                                            
                            
            
                                    
            
            
                | 117 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 118 |  |  |     def __repr__(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 119 |  |  |         if hasattr(self, 'args_names'): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 120 |  |  |             names = self.args_names | 
            
                                                                                                            
                            
            
                                    
            
            
                | 121 |  |  |             args_strings = [f'{arg}={getattr(self, arg)}' for arg in names] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 122 |  |  |             if hasattr(self, 'invert_transform') and self.invert_transform: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 123 |  |  |                 args_strings.append('invert=True') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 124 |  |  |             args_string = ', '.join(args_strings) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 125 |  |  |             return f'{self.name}({args_string})' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 126 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 127 |  |  |             return super().__repr__() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 128 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 129 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 130 |  |  |     def name(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 131 |  |  |         return self.__class__.__name__ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 132 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 133 |  |  |     @abstractmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 134 |  |  |     def apply_transform(self, subject: Subject): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 135 |  |  |         raise NotImplementedError | 
            
                                                                                                            
                            
            
                                    
            
            
                | 136 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 137 |  |  |     def add_transform_to_subject_history(self, subject): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 138 |  |  |         from .augmentation import RandomTransform | 
            
                                                                                                            
                            
            
                                    
            
            
                | 139 |  |  |         from . import Compose, OneOf, CropOrPad, EnsureShapeMultiple | 
            
                                                                                                            
                            
            
                                    
            
            
                | 140 |  |  |         from .preprocessing.label import SequentialLabels | 
            
                                                                                                            
                            
            
                                    
            
            
                | 141 |  |  |         call_others = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 142 |  |  |             RandomTransform, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 143 |  |  |             Compose, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 144 |  |  |             OneOf, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 145 |  |  |             CropOrPad, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 146 |  |  |             EnsureShapeMultiple, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 147 |  |  |             SequentialLabels, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 148 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 149 |  |  |         if not isinstance(self, call_others): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 150 |  |  |             subject.add_transform(self, self._get_reproducing_arguments()) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 151 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 152 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 153 |  |  |     def to_range(n, around): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 154 |  |  |         if around is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 155 |  |  |             return 0, n | 
            
                                                                                                            
                            
            
                                    
            
            
                | 156 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 157 |  |  |             return around - n, around + n | 
            
                                                                                                            
                            
            
                                    
            
            
                | 158 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 159 |  |  |     def parse_params(self, params, around, name, make_ranges=True, **kwargs): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 160 |  |  |         params = to_tuple(params) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 161 |  |  |         # d or (a, b) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 162 |  |  |         if len(params) == 1 or (len(params) == 2 and make_ranges): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 163 |  |  |             params *= 3  # (d, d, d) or (a, b, a, b, a, b) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 164 |  |  |         if len(params) == 3 and make_ranges:  # (a, b, c) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 165 |  |  |             items = [self.to_range(n, around) for n in params] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 166 |  |  |             # (-a, a, -b, b, -c, c) or (1-a, 1+a, 1-b, 1+b, 1-c, 1+c) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 167 |  |  |             params = [n for prange in items for n in prange] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 168 |  |  |         if make_ranges: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 169 |  |  |             if len(params) != 6: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 170 |  |  |                 message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 171 |  |  |                     f'If "{name}" is a sequence, it must have length 2, 3 or' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 172 |  |  |                     f' 6, not {len(params)}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 173 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 174 |  |  |                 raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 175 |  |  |             for param_range in zip(params[::2], params[1::2]): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 176 |  |  |                 self._parse_range(param_range, name, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 177 |  |  |         return tuple(params) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 178 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 179 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 180 |  |  |     def _parse_range( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 181 |  |  |             nums_range: Union[TypeNumber, Tuple[TypeNumber, TypeNumber]], | 
            
                                                                                                            
                            
            
                                    
            
            
                | 182 |  |  |             name: str, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 183 |  |  |             min_constraint: TypeNumber = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 184 |  |  |             max_constraint: TypeNumber = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 185 |  |  |             type_constraint: type = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 186 |  |  |             ) -> Tuple[TypeNumber, TypeNumber]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 187 |  |  |         r"""Adapted from :class:`torchvision.transforms.RandomRotation`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 188 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 189 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 190 |  |  |             nums_range: Tuple of two numbers :math:`(n_{min}, n_{max})`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 191 |  |  |                 where :math:`n_{min} \leq n_{max}`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 192 |  |  |                 If a single positive number :math:`n` is provided, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 193 |  |  |                 :math:`n_{min} = -n` and :math:`n_{max} = n`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 194 |  |  |             name: Name of the parameter, so that an informative error message | 
            
                                                                                                            
                            
            
                                    
            
            
                | 195 |  |  |                 can be printed. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 196 |  |  |             min_constraint: Minimal value that :math:`n_{min}` can take, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 197 |  |  |                 default is None, i.e. there is no minimal value. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 198 |  |  |             max_constraint: Maximal value that :math:`n_{max}` can take, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 199 |  |  |                 default is None, i.e. there is no maximal value. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 200 |  |  |             type_constraint: Precise type that :math:`n_{max}` and | 
            
                                                                                                            
                            
            
                                    
            
            
                | 201 |  |  |                 :math:`n_{min}` must take. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 202 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 203 |  |  |         Returns: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 204 |  |  |             A tuple of two numbers :math:`(n_{min}, n_{max})`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 205 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 206 |  |  |         Raises: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 207 |  |  |             ValueError: if :attr:`nums_range` is negative | 
            
                                                                                                            
                            
            
                                    
            
            
                | 208 |  |  |             ValueError: if :math:`n_{max}` or :math:`n_{min}` is not a number | 
            
                                                                                                            
                            
            
                                    
            
            
                | 209 |  |  |             ValueError: if :math:`n_{max} \lt n_{min}` | 
            
                                                                                                            
                            
            
                                    
            
            
                | 210 |  |  |             ValueError: if :attr:`min_constraint` is not None and | 
            
                                                                                                            
                            
            
                                    
            
            
                | 211 |  |  |                 :math:`n_{min}` is smaller than :attr:`min_constraint` | 
            
                                                                                                            
                            
            
                                    
            
            
                | 212 |  |  |             ValueError: if :attr:`max_constraint` is not None and | 
            
                                                                                                            
                            
            
                                    
            
            
                | 213 |  |  |                 :math:`n_{max}` is greater than :attr:`max_constraint` | 
            
                                                                                                            
                            
            
                                    
            
            
                | 214 |  |  |             ValueError: if :attr:`type_constraint` is not None and | 
            
                                                                                                            
                            
            
                                    
            
            
                | 215 |  |  |                 :math:`n_{max}` and :math:`n_{max}` are not of type | 
            
                                                                                                            
                            
            
                                    
            
            
                | 216 |  |  |                 :attr:`type_constraint`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 217 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 218 |  |  |         if isinstance(nums_range, numbers.Number):  # single number given | 
            
                                                                                                            
                            
            
                                    
            
            
                | 219 |  |  |             if nums_range < 0: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 220 |  |  |                 raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 221 |  |  |                     f'If {name} is a single number,' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 222 |  |  |                     f' it must be positive, not {nums_range}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 223 |  |  |             if min_constraint is not None and nums_range < min_constraint: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 224 |  |  |                 raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 225 |  |  |                     f'If {name} is a single number, it must be greater' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 226 |  |  |                     f' than {min_constraint}, not {nums_range}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 227 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 228 |  |  |             if max_constraint is not None and nums_range > max_constraint: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 229 |  |  |                 raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 230 |  |  |                     f'If {name} is a single number, it must be smaller' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 231 |  |  |                     f' than {max_constraint}, not {nums_range}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 232 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 233 |  |  |             if type_constraint is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 234 |  |  |                 if not isinstance(nums_range, type_constraint): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 235 |  |  |                     raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 236 |  |  |                         f'If {name} is a single number, it must be of' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 237 |  |  |                         f' type {type_constraint}, not {nums_range}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 238 |  |  |                     ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 239 |  |  |             min_range = -nums_range if min_constraint is None else nums_range | 
            
                                                                                                            
                            
            
                                    
            
            
                | 240 |  |  |             return (min_range, nums_range) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 241 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 242 |  |  |         try: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 243 |  |  |             min_value, max_value = nums_range | 
            
                                                                                                            
                            
            
                                    
            
            
                | 244 |  |  |         except (TypeError, ValueError): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 245 |  |  |             raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 246 |  |  |                 f'If {name} is not a single number, it must be' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 247 |  |  |                 f' a sequence of len 2, not {nums_range}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 248 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 249 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 250 |  |  |         min_is_number = isinstance(min_value, numbers.Number) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 251 |  |  |         max_is_number = isinstance(max_value, numbers.Number) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 252 |  |  |         if not min_is_number or not max_is_number: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 253 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 254 |  |  |                 f'{name} values must be numbers, not {nums_range}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 255 |  |  |             raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 256 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 257 |  |  |         if min_value > max_value: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 258 |  |  |             raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 259 |  |  |                 f'If {name} is a sequence, the second value must be' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 260 |  |  |                 f' equal or greater than the first, but it is {nums_range}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 261 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 262 |  |  |         if min_constraint is not None and min_value < min_constraint: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 263 |  |  |             raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 264 |  |  |                 f'If {name} is a sequence, the first value must be greater' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 265 |  |  |                 f' than {min_constraint}, but it is {min_value}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 266 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 267 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 268 |  |  |         if max_constraint is not None and max_value > max_constraint: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 269 |  |  |             raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 270 |  |  |                 f'If {name} is a sequence, the second value must be smaller' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 271 |  |  |                 f' than {max_constraint}, but it is {max_value}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 272 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 273 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 274 |  |  |         if type_constraint is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 275 |  |  |             min_type_ok = isinstance(min_value, type_constraint) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 276 |  |  |             max_type_ok = isinstance(max_value, type_constraint) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 277 |  |  |             if not min_type_ok or not max_type_ok: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 278 |  |  |                 raise ValueError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 279 |  |  |                     f'If "{name}" is a sequence, its values must be of' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 280 |  |  |                     f' type "{type_constraint}", not "{type(nums_range)}"' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 281 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 282 |  |  |         return nums_range | 
            
                                                                                                            
                            
            
                                    
            
            
                | 283 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 284 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 285 |  |  |     def parse_interpolation(interpolation: str) -> str: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 286 |  |  |         if not isinstance(interpolation, str): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 287 |  |  |             itype = type(interpolation) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 288 |  |  |             raise TypeError(f'Interpolation must be a string, not {itype}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 289 |  |  |         interpolation = interpolation.lower() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 290 |  |  |         is_string = isinstance(interpolation, str) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 291 |  |  |         supported_values = [key.name.lower() for key in Interpolation] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 292 |  |  |         is_supported = interpolation.lower() in supported_values | 
            
                                                                                                            
                            
            
                                    
            
            
                | 293 |  |  |         if is_string and is_supported: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 294 |  |  |             return interpolation | 
            
                                                                                                            
                            
            
                                    
            
            
                | 295 |  |  |         message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 296 |  |  |             f'Interpolation "{interpolation}" of type {type(interpolation)}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 297 |  |  |             f' must be a string among the supported values: {supported_values}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 298 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 299 |  |  |         raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 300 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 301 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 302 |  |  |     def parse_probability(probability: float) -> float: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 303 |  |  |         is_number = isinstance(probability, numbers.Number) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 304 |  |  |         if not (is_number and 0 <= probability <= 1): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 305 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 306 |  |  |                 'Probability must be a number in [0, 1],' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 307 |  |  |                 f' not {probability}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 308 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 309 |  |  |             raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 310 |  |  |         return probability | 
            
                                                                                                            
                            
            
                                    
            
            
                | 311 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 312 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 313 |  |  |     def parse_include_and_exclude( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 314 |  |  |             include: TypeKeys = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 315 |  |  |             exclude: TypeKeys = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 316 |  |  |             ) -> Tuple[TypeKeys, TypeKeys]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 317 |  |  |         if include is not None and exclude is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 318 |  |  |             raise ValueError('Include and exclude cannot both be specified') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 319 |  |  |         return include, exclude | 
            
                                                                                                            
                            
            
                                    
            
            
                | 320 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 321 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 322 |  |  |     def nib_to_sitk(data: TypeData, affine: TypeData) -> sitk.Image: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 323 |  |  |         return nib_to_sitk(data, affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 324 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 325 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 326 |  |  |     def sitk_to_nib(image: sitk.Image) -> Tuple[torch.Tensor, np.ndarray]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 327 |  |  |         return sitk_to_nib(image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 328 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 329 |  |  |     def _get_reproducing_arguments(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 330 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 331 |  |  |         Return a dictionary with the arguments that would be necessary to | 
            
                                                                                                            
                            
            
                                    
            
            
                | 332 |  |  |         reproduce the transform exactly. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 333 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 334 |  |  |         reproducing_arguments = { | 
            
                                                                                                            
                            
            
                                    
            
            
                | 335 |  |  |             'include': self.include, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 336 |  |  |             'exclude': self.exclude, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 337 |  |  |             'copy': self.copy, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 338 |  |  |         } | 
            
                                                                                                            
                            
            
                                    
            
            
                | 339 |  |  |         args_names = {name: getattr(self, name) for name in self.args_names} | 
            
                                                                                                            
                            
            
                                    
            
            
                | 340 |  |  |         reproducing_arguments.update(args_names) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 341 |  |  |         return reproducing_arguments | 
            
                                                                                                            
                            
            
                                    
            
            
                | 342 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 343 |  |  |     def is_invertible(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 344 |  |  |         return hasattr(self, 'invert_transform') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 345 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 346 |  |  |     def inverse(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 347 |  |  |         if not self.is_invertible(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 348 |  |  |             raise RuntimeError(f'{self.name} is not invertible') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 349 |  |  |         new = copy.deepcopy(self) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 350 |  |  |         new.invert_transform = not self.invert_transform | 
            
                                                                                                            
                            
            
                                    
            
            
                | 351 |  |  |         return new | 
            
                                                                                                            
                            
            
                                    
            
            
                | 352 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 353 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 354 |  |  |     @contextmanager | 
            
                                                                                                            
                            
            
                                    
            
            
                | 355 |  |  |     def _use_seed(seed): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 356 |  |  |         """Perform an operation using a specific seed for the PyTorch RNG""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 357 |  |  |         torch_rng_state = torch.random.get_rng_state() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 358 |  |  |         torch.manual_seed(seed) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 359 |  |  |         yield | 
            
                                                                                                            
                            
            
                                    
            
            
                | 360 |  |  |         torch.random.set_rng_state(torch_rng_state) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 361 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 362 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 363 |  |  |     def get_sitk_interpolator(interpolation: str) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 364 |  |  |         return get_sitk_interpolator(interpolation) | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 365 |  |  |  | 
            
                                                                        
                            
            
                                    
            
            
                | 366 |  |  |     @staticmethod | 
            
                                                                        
                            
            
                                    
            
            
                | 367 |  |  |     def parse_bounds(bounds_parameters: TypeBounds) -> TypeSixBounds: | 
            
                                                                        
                            
            
                                    
            
            
                | 368 |  |  |         try: | 
            
                                                                        
                            
            
                                    
            
            
                | 369 |  |  |             bounds_parameters = tuple(bounds_parameters) | 
            
                                                                        
                            
            
                                    
            
            
                | 370 |  |  |         except TypeError: | 
            
                                                                        
                            
            
                                    
            
            
                | 371 |  |  |             bounds_parameters = (bounds_parameters,) | 
            
                                                                        
                            
            
                                    
            
            
                | 372 |  |  |  | 
            
                                                                        
                            
            
                                    
            
            
                | 373 |  |  |         # Check that numbers are integers | 
            
                                                                        
                            
            
                                    
            
            
                | 374 |  |  |         for number in bounds_parameters: | 
            
                                                                        
                            
            
                                    
            
            
                | 375 |  |  |             if not isinstance(number, (int, np.integer)) or number < 0: | 
            
                                                                        
                            
            
                                    
            
            
                | 376 |  |  |                 message = ( | 
            
                                                                        
                            
            
                                    
            
            
                | 377 |  |  |                     'Bounds values must be integers greater or equal to zero,' | 
            
                                                                        
                            
            
                                    
            
            
                | 378 |  |  |                     f' not "{bounds_parameters}" of type {type(number)}' | 
            
                                                                        
                            
            
                                    
            
            
                | 379 |  |  |                 ) | 
            
                                                                        
                            
            
                                    
            
            
                | 380 |  |  |                 raise ValueError(message) | 
            
                                                                        
                            
            
                                    
            
            
                | 381 |  |  |         bounds_parameters = tuple(int(n) for n in bounds_parameters) | 
            
                                                                        
                            
            
                                    
            
            
                | 382 |  |  |         bounds_parameters_length = len(bounds_parameters) | 
            
                                                                        
                            
            
                                    
            
            
                | 383 |  |  |         if bounds_parameters_length == 6: | 
            
                                                                        
                            
            
                                    
            
            
                | 384 |  |  |             return bounds_parameters | 
            
                                                                        
                            
            
                                    
            
            
                | 385 |  |  |         if bounds_parameters_length == 1: | 
            
                                                                        
                            
            
                                    
            
            
                | 386 |  |  |             return 6 * bounds_parameters | 
            
                                                                        
                            
            
                                    
            
            
                | 387 |  |  |         if bounds_parameters_length == 3: | 
            
                                                                        
                            
            
                                    
            
            
                | 388 |  |  |             return tuple(np.repeat(bounds_parameters, 2).tolist()) | 
            
                                                                        
                            
            
                                    
            
            
                | 389 |  |  |         message = ( | 
            
                                                                        
                            
            
                                    
            
            
                | 390 |  |  |             'Bounds parameter must be an integer or a tuple of' | 
            
                                                                        
                            
            
                                    
            
            
                | 391 |  |  |             f' 3 or 6 integers, not {bounds_parameters}' | 
            
                                                                        
                            
            
                                    
            
            
                | 392 |  |  |         ) | 
            
                                                                        
                            
            
                                    
            
            
                | 393 |  |  |         raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 394 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 395 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 396 |  |  |     def ones(tensor: torch.Tensor) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 397 |  |  |         return torch.ones_like(tensor, dtype=torch.bool) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 398 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 399 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 400 |  |  |     def mean(tensor: torch.Tensor) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 401 |  |  |         mask = tensor > tensor.mean() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 402 |  |  |         return mask | 
            
                                                                                                            
                            
            
                                    
            
            
                | 403 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 404 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 405 |  |  |     def get_mask_from_masking_method( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 406 |  |  |             masking_method: TypeMaskingMethod, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 407 |  |  |             subject: Subject, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 408 |  |  |             tensor: torch.Tensor, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 409 |  |  |             ) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 410 |  |  |         if masking_method is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 411 |  |  |             return Transform.ones(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 412 |  |  |         elif callable(masking_method): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 413 |  |  |             return masking_method(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 414 |  |  |         elif type(masking_method) is str: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 415 |  |  |             in_subject = masking_method in subject | 
            
                                                                                                            
                            
            
                                    
            
            
                | 416 |  |  |             if in_subject and isinstance(subject[masking_method], LabelMap): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 417 |  |  |                 return subject[masking_method].data.bool() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 418 |  |  |             masking_method = masking_method.capitalize() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 419 |  |  |             if masking_method in anat_axes: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 420 |  |  |                 return Transform.get_mask_from_anatomical_label( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 421 |  |  |                     masking_method, tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 422 |  |  |         elif type(masking_method) in (tuple, list, int): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 423 |  |  |             return Transform.get_mask_from_bounds(masking_method, tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 424 |  |  |         message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 425 |  |  |             'Masking method parameter must be a function, a label map name,' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 426 |  |  |             f' an anatomical label: {anat_axes}, or a bounds parameter' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 427 |  |  |             ' (an int, tuple of 3 ints, or tuple of 6 ints),' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 428 |  |  |             f' not {masking_method} of type {type(masking_method)}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 429 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 430 |  |  |         raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 431 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 432 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 433 |  |  |     def get_mask_from_anatomical_label( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 434 |  |  |             anatomical_label: str, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 435 |  |  |             tensor: torch.Tensor, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 436 |  |  |             ) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 437 |  |  |         anatomical_label = anatomical_label.title() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 438 |  |  |         if anatomical_label.title() not in anat_axes: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 439 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 440 |  |  |                 f'Anatomical label must be one of {anat_axes}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 441 |  |  |                 f' not {anatomical_label}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 442 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 443 |  |  |             raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 444 |  |  |         mask = torch.zeros_like(tensor, dtype=torch.bool) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 445 |  |  |         _, width, height, depth = tensor.shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 446 |  |  |         if anatomical_label == 'Right': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 447 |  |  |             mask[:, width // 2:] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 448 |  |  |         elif anatomical_label == 'Left': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 449 |  |  |             mask[:, :width // 2] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 450 |  |  |         elif anatomical_label == 'Anterior': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 451 |  |  |             mask[:, :, height // 2:] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 452 |  |  |         elif anatomical_label == 'Posterior': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 453 |  |  |             mask[:, :, :height // 2] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 454 |  |  |         elif anatomical_label == 'Superior': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 455 |  |  |             mask[:, :, :, depth // 2:] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 456 |  |  |         elif anatomical_label == 'Inferior': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 457 |  |  |             mask[:, :, :, :depth // 2] = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 458 |  |  |         return mask | 
            
                                                                                                            
                            
            
                                    
            
            
                | 459 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 460 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 461 |  |  |     def get_mask_from_bounds( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 462 |  |  |             bounds_parameters: TypeBounds, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 463 |  |  |             tensor: torch.Tensor, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 464 |  |  |             ) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 465 |  |  |         bounds_parameters = Transform.parse_bounds(bounds_parameters) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 466 |  |  |         low = bounds_parameters[::2] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 467 |  |  |         high = bounds_parameters[1::2] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 468 |  |  |         i0, j0, k0 = low | 
            
                                                                                                            
                            
            
                                    
            
            
                | 469 |  |  |         i1, j1, k1 = np.array(tensor.shape[1:]) - high | 
            
                                                                                                            
                            
            
                                    
            
            
                | 470 |  |  |         mask = torch.zeros_like(tensor, dtype=torch.bool) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 471 |  |  |         mask[:, i0:i1, j0:j1, k0:k1] = True | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 472 |  |  |         return mask | 
            
                                                        
            
                                    
            
            
                | 473 |  |  |  |