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                from __future__ import annotations  | 
            
                            
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                    2
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                import abc  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    3
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                import enum  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    4
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                import sys  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    5
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                import sre_compile  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    6
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                import re  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    7
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                from pathlib import Path  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    8
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                from typing import Dict, Sequence, Type, Set, Optional, Mapping  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    9
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                from typing import Tuple as Tup  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    10
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                    11
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                from mandos.model import MandosResources  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    12
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                from mandos.model.chembl_api import ChemblApi  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    13
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                from mandos.model.chembl_support.chembl_targets import TargetType, ChemblTarget  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    14
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                from mandos.model.chembl_support.chembl_target_graphs import (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    15
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                    ChemblTargetGraph,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    16
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                    TargetNode,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    17
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                    TargetEdgeReqs,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    18
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                    TargetRelType,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    19
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                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    20
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                    21
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                    22
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                class Acceptance(enum.Enum):  | 
            
                            
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                    23
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                    always = enum.auto()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    24
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                    never = enum.auto()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    25
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                    at_start = enum.auto()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    26
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                    at_end = enum.auto()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    27
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                    28
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                    29
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                class TargetTraversalStrategy(metaclass=abc.ABCMeta):  | 
            
                            
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                    30
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                    """"""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    31
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                    32
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                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    33
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                    def api(cls) -> ChemblApi:  | 
            
                            
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                    34
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                        raise NotImplementedError()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    35
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                    36
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                    def traverse(self, target: ChemblTargetGraph) -> Sequence[ChemblTargetGraph]:  | 
            
                            
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                    37
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                        return self.__call__(target)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    38
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                    39
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                    def __call__(self, target: ChemblTargetGraph) -> Sequence[ChemblTargetGraph]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    40
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                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    41
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                    42
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                        Returns:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    43
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                    44
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                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    45
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                        raise NotImplementedError()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    46
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                    47
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                    48
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                class StandardTargetTraversalStrategy(TargetTraversalStrategy, metaclass=abc.ABCMeta):  | 
            
                            
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                    49
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                    """"""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    50
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                    51
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                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    52
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                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    53
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                    def edges(cls) -> Set[TargetEdgeReqs]:  | 
            
                            
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                    54
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                        raise NotImplementedError()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    55
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                    56
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                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    57
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                    @property  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    58
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                    def acceptance(cls) -> Mapping[TargetEdgeReqs, Acceptance]:  | 
            
                            
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                    59
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                        raise NotImplementedError()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    60
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                    61
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                    def __call__(self, target: ChemblTargetGraph) -> Sequence[ChemblTarget]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    62
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                        if not target.type.is_traversable:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    63
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                            return [target.target]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    64
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                        found = target.traverse(self.edges)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    65
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                        return [f.target for f in found if self.accept(f)]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    66
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                    67
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                    def accept(self, target: TargetNode) -> bool:  | 
            
                            
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                    68
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                        acceptance_type = self.acceptance[target.link_reqs]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    69
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                        return (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    70
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                            acceptance_type is Acceptance.always  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    71
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                            or (acceptance_type is Acceptance.at_start and target.is_start)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    72
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                            or (acceptance_type is Acceptance.at_end and target.is_end)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    73
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                        )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    74
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                    75
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                    76
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                class StandardStrategyParser:  | 
            
                            
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                    77
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                    @classmethod  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    78
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                    def read_lines(cls, path: Path) -> Sequence[str]:  | 
            
                            
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                    79
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                        return [  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    80
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                            line  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    81
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                            for line in path.read_text(encoding="utf8").splitlines()  | 
            
            
                                                                        
                            
            
                                    
            
            
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                    82
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                            if not line.startswith("#") and len(line.strip()) > 0 | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    83
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                        ]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    84
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                    85
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                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    86
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                    def parse(  | 
            
                            
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                    87
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                        cls, lines: Sequence[str]  | 
            
                            
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                | 
                    88
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                    ) -> Tup[Set[TargetEdgeReqs], Mapping[TargetEdgeReqs, Acceptance]]:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    89
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                        pat_type = r"([a-z_]+)"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    90
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                        pat_rel = r"([<>~=])"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    91
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                        pat_accept = r"(?:accept:([\-*^$]?))?"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    92
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                        pat_src_words = r"(?:src:'''(.+?)''')?"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    93
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                        pat_dest_words = r"(?:dest:'''(.+?)''')?"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
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                    94
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                        comment = r"(?:#(.*))?"  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    95
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                        pat = f"^ *{pat_type} *{pat_rel} *{pat_type} *{pat_accept} * {pat_src_words} *{pat_dest_words} *{comment} *$" | 
            
                            
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                | 
                    96
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                        pat = re.compile(pat)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    97
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                        to_rel = { | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    98
                 | 
                                    
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                 | 
                            ">": TargetRelType.superset_of,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    99
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                 | 
                            "<": TargetRelType.subset_of,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    100
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                                                     | 
                
                 | 
                            "~": TargetRelType.overlaps_with,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    101
                 | 
                                    
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                 | 
                            "=": TargetRelType.equivalent_to,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    102
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                            "*": TargetRelType.any_link,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    103
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                 | 
                            ".": TargetRelType.self_link,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    104
                 | 
                                    
                                                     | 
                
                 | 
                        }  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    105
                 | 
                                    
                                                     | 
                
                 | 
                        to_accept = { | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    106
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                            "*": Acceptance.always,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    107
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                            "-": Acceptance.never,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    108
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                 | 
                            "^": Acceptance.at_start,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    109
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                                                     | 
                
                 | 
                            "$": Acceptance.at_end,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    110
                 | 
                                    
                                                     | 
                
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                        }  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    111
                 | 
                                    
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                 | 
                        edges = set()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    112
                 | 
                                    
                                                     | 
                
                 | 
                        edge_to_acceptance: Dict[TargetEdgeReqs, Acceptance] = {} | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    113
                 | 
                                    
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                 | 
                        for line in lines:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    114
                 | 
                                    
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                 | 
                            match = pat.fullmatch(line)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    115
                 | 
                                    
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                 | 
                            if match is None:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    116
                 | 
                                    
                                                     | 
                
                 | 
                                raise AssertionError(f"Could not parse line '{line}'") | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    117
                 | 
                                    
                                                     | 
                
                 | 
                            try:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    118
                 | 
                                    
                                                     | 
                
                 | 
                                src_str = match.group(1).lower()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    119
                 | 
                                    
                                                     | 
                
                 | 
                                sources = TargetType.all_types() if src_str == "any" else [TargetType[src_str]]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    120
                 | 
                                    
                                                     | 
                
                 | 
                                rel = to_rel[match.group(2)]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    121
                 | 
                                    
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                 | 
                                dest_str = match.group(3).lower()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    122
                 | 
                                    
                                                     | 
                
                 | 
                                targets = TargetType.all_types() if dest_str == "any" else [TargetType[dest_str]]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    123
                 | 
                                    
                                                     | 
                
                 | 
                                accept = to_accept[match.group(4).lower()]  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    124
                 | 
                                    
                                                     | 
                
                 | 
                                src_pat = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    125
                 | 
                                    
                                                     | 
                
                 | 
                                    None  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    126
                 | 
                                    
                                                     | 
                
                 | 
                                    if match.group(5) is None or match.group(5) == ""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    127
                 | 
                                    
                                                     | 
                
                 | 
                                    else re.compile(match.group(5))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    128
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    129
                 | 
                                    
                                                     | 
                
                 | 
                                dest_pat = (  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    130
                 | 
                                    
                                                     | 
                
                 | 
                                    None  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    131
                 | 
                                    
                                                     | 
                
                 | 
                                    if match.group(6) is None or match.group(6) == ""  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    132
                 | 
                                    
                                                     | 
                
                 | 
                                    else re.compile(match.group(6))  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    133
                 | 
                                    
                                                     | 
                
                 | 
                                )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    134
                 | 
                                    
                                                     | 
                
                 | 
                            except (KeyError, TypeError, sre_compile.error):  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    135
                 | 
                                    
                                                     | 
                
                 | 
                                raise AssertionError(f"Could not parse line '{line}'") | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    136
                 | 
                                    
                                                     | 
                
                 | 
                            for source in sources:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    137
                 | 
                                    
                                                     | 
                
                 | 
                                for dest in targets:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    138
                 | 
                                    
                                                     | 
                
                 | 
                                    edge = TargetEdgeReqs(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    139
                 | 
                                    
                                                     | 
                
                 | 
                                        src_type=source,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    140
                 | 
                                    
                                                     | 
                
                 | 
                                        src_pattern=src_pat,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    141
                 | 
                                    
                                                     | 
                
                 | 
                                        rel_type=rel,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    142
                 | 
                                    
                                                     | 
                
                 | 
                                        dest_type=dest,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    143
                 | 
                                    
                                                     | 
                
                 | 
                                        dest_pattern=dest_pat,  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    144
                 | 
                                    
                                                     | 
                
                 | 
                                    )  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    145
                 | 
                                    
                                                     | 
                
                 | 
                                    edges.add(edge)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    146
                 | 
                                    
                                                     | 
                
                 | 
                                    edge_to_acceptance[edge] = accept  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    147
                 | 
                                    
                                                     | 
                
                 | 
                        return edges, edge_to_acceptance  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    148
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    149
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    150
                 | 
                                    
                                                     | 
                
                 | 
                class TargetTraversalStrategies:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    151
                 | 
                                    
                                                     | 
                
                 | 
                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    152
                 | 
                                    
                                                     | 
                
                 | 
                    Factory.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    153
                 | 
                                    
                                                     | 
                
                 | 
                    """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    154
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    155
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    156
                 | 
                                    
                                                     | 
                
                 | 
                    def by_name(cls, fully_qualified: str, api: ChemblApi) -> TargetTraversalStrategy:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    157
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    158
                 | 
                                    
                                                     | 
                
                 | 
                        For dependency injection.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    159
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    160
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    161
                 | 
                                    
                                                     | 
                
                 | 
                            fully_qualified:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    162
                 | 
                                    
                                                     | 
                
                 | 
                            api:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    163
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    164
                 | 
                                    
                                                     | 
                
                 | 
                        Returns:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    165
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    166
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    167
                 | 
                                    
                                                     | 
                
                 | 
                        s = fully_qualified  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    168
                 | 
                                    
                                                     | 
                
                 | 
                        mod = s[: s.rfind(".")] | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    169
                 | 
                                    
                                                     | 
                
                 | 
                        clz = s[s.rfind(".") :] | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    170
                 | 
                                    
                                                     | 
                
                 | 
                        x = getattr(sys.modules[mod], clz)  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    171
                 | 
                                    
                                                     | 
                
                 | 
                        return cls.create(x, api)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    172
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    173
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    174
                 | 
                                    
                                                     | 
                
                 | 
                    def from_resource(cls, name: str, api: ChemblApi) -> TargetTraversalStrategy:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    175
                 | 
                                    
                                                     | 
                
                 | 
                        path = MandosResources.path("strategies", name).with_suffix(".txt") | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    176
                 | 
                                    
                                                     | 
                
                 | 
                        lines = StandardStrategyParser.read_lines(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    177
                 | 
                                    
                                                     | 
                
                 | 
                        return cls._from_lines(lines, api, path.stem)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    178
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    179
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    180
                 | 
                                    
                                                     | 
                
                 | 
                    def from_file(cls, path: Path, api: ChemblApi) -> TargetTraversalStrategy:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    181
                 | 
                                    
                                                     | 
                
                 | 
                        lines = StandardStrategyParser.read_lines(path)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    182
                 | 
                                    
                                                     | 
                
                 | 
                        return cls._from_lines(lines, api, path.stem)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    183
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    184
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    185
                 | 
                                    
                                                     | 
                
                 | 
                    def from_lines(  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    186
                 | 
                                    
                                                     | 
                
                 | 
                        cls, lines: Sequence[str], api: ChemblApi, name: Optional[str]  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    187
                 | 
                                    
                                                     | 
                
                 | 
                    ) -> TargetTraversalStrategy:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    188
                 | 
                                    
                                                     | 
                
                 | 
                        return cls._from_lines(lines, api, "" if name is None else name)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    189
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    190
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    191
                 | 
                                    
                                                     | 
                
                 | 
                    def _from_lines(  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    192
                 | 
                                    
                                                     | 
                
                 | 
                        cls, lines: Sequence[str], api: ChemblApi, name: str  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    193
                 | 
                                    
                                                     | 
                
                 | 
                    ) -> TargetTraversalStrategy:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    194
                 | 
                                    
                                                     | 
                
                 | 
                        edges, accept = StandardStrategyParser.parse(lines)  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    195
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    196
                 | 
                                    
                                                     | 
                
                 | 
                        class Strategy(StandardTargetTraversalStrategy):  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    197
                 | 
                                    
                                                     | 
                
                 | 
                            @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    198
                 | 
                                    
                                                     | 
                
                 | 
                            def edges(cls) -> Set[TargetEdgeReqs]:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    199
                 | 
                                    
                                                     | 
                
                 | 
                                return edges  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    200
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    201
                 | 
                                    
                                                     | 
                
                 | 
                            @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    202
                 | 
                                    
                                                     | 
                
                 | 
                            def acceptance(cls) -> Mapping[TargetEdgeReqs, Acceptance]:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    203
                 | 
                                    
                                                     | 
                
                 | 
                                return accept  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    204
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    205
                 | 
                                    
                                                     | 
                
                 | 
                            @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    206
                 | 
                                    
                                                     | 
                
                 | 
                            def api(cls) -> ChemblApi:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    207
                 | 
                                    
                                                     | 
                
                 | 
                                return api  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    208
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    209
                 | 
                                    
                                                     | 
                
                 | 
                        Strategy.__name__ = StandardTargetTraversalStrategy.__class__.__name__ + "_" + name  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    210
                 | 
                                    
                                                     | 
                
                 | 
                        return Strategy()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    211
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    212
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    213
                 | 
                                    
                                                     | 
                
                 | 
                    def null(cls, api: ChemblApi) -> TargetTraversalStrategy:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    214
                 | 
                                    
                                                     | 
                
                 | 
                        return cls.from_resource("null.txt", api) | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    215
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    216
                 | 
                                    
                                                     | 
                
                 | 
                    # noinspection PyAbstractClass  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    217
                 | 
                                    
                                                     | 
                
                 | 
                    @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    218
                 | 
                                    
                                                     | 
                
                 | 
                    def create(cls, clz: Type[TargetTraversalStrategy], api: ChemblApi) -> TargetTraversalStrategy:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    219
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    220
                 | 
                                    
                                                     | 
                
                 | 
                        Factory method.  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    221
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    222
                 | 
                                    
                                                     | 
                
                 | 
                        Args:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    223
                 | 
                                    
                                                     | 
                
                 | 
                            clz:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    224
                 | 
                                    
                                                     | 
                
                 | 
                            api:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    225
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    226
                 | 
                                    
                                                     | 
                
                 | 
                        Returns:  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    227
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    228
                 | 
                                    
                                                     | 
                
                 | 
                        """  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    229
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    230
                 | 
                                    
                                                     | 
                
                 | 
                        class X(clz):  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                                                                        
                        
                         
                                                                                        
                                                                                            
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    231
                 | 
                                    
                                                     | 
                
                 | 
                            @classmethod  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    232
                 | 
                                    
                                                     | 
                
                 | 
                            def api(cls) -> ChemblApi:  | 
            
                            
                    | 
                        
                     | 
                     | 
                     | 
                    
                                                                                                    
                        
                         
                                                                                        
                                                                                     
                     | 
                
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    233
                 | 
                                    
                                                     | 
                
                 | 
                                return api  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    234
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    235
                 | 
                                    
                                                     | 
                
                 | 
                        X.__name__ = clz.__name__  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    236
                 | 
                                    
                                                     | 
                
                 | 
                        return X()  | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    237
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                            
            
                                    
            
            
                | 
                    238
                 | 
                                    
                                                     | 
                
                 | 
                 | 
            
            
                                                                                                            
                                                                
            
                                    
            
            
                | 
                    239
                 | 
                                    
                                                     | 
                
                 | 
                __all__ = ["TargetTraversalStrategy", "TargetTraversalStrategies"]  | 
            
            
                                                        
            
                                    
            
            
                | 
                    240
                 | 
                                    
                                                     | 
                
                 | 
                 |