| 1 |  |  | from __future__ import annotations | 
            
                                                                                                            
                            
            
                                    
            
            
                | 2 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 3 |  |  | import warnings | 
            
                                                                                                            
                            
            
                                    
            
            
                | 4 |  |  | from collections import Counter | 
            
                                                                                                            
                            
            
                                    
            
            
                | 5 |  |  | from collections.abc import Sequence | 
            
                                                                                                            
                            
            
                                    
            
            
                | 6 |  |  | from pathlib import Path | 
            
                                                                                                            
                            
            
                                    
            
            
                | 7 |  |  | from typing import Any | 
            
                                                                                                            
                            
            
                                    
            
            
                | 8 |  |  | from typing import Callable | 
            
                                                                                                            
                            
            
                                    
            
            
                | 9 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 10 |  |  | import humanize | 
            
                                                                                                            
                            
            
                                    
            
            
                | 11 |  |  | import nibabel as nib | 
            
                                                                                                            
                            
            
                                    
            
            
                | 12 |  |  | import numpy as np | 
            
                                                                                                            
                            
            
                                    
            
            
                | 13 |  |  | import SimpleITK as sitk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 14 |  |  | import torch | 
            
                                                                                                            
                            
            
                                    
            
            
                | 15 |  |  | from deprecated import deprecated | 
            
                                                                                                            
                            
            
                                    
            
            
                | 16 |  |  | from nibabel.affines import apply_affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 17 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 18 |  |  | from ..constants import AFFINE | 
            
                                                                                                            
                            
            
                                    
            
            
                | 19 |  |  | from ..constants import DATA | 
            
                                                                                                            
                            
            
                                    
            
            
                | 20 |  |  | from ..constants import INTENSITY | 
            
                                                                                                            
                            
            
                                    
            
            
                | 21 |  |  | from ..constants import LABEL | 
            
                                                                                                            
                            
            
                                    
            
            
                | 22 |  |  | from ..constants import PATH | 
            
                                                                                                            
                            
            
                                    
            
            
                | 23 |  |  | from ..constants import STEM | 
            
                                                                                                            
                            
            
                                    
            
            
                | 24 |  |  | from ..constants import TENSOR | 
            
                                                                                                            
                            
            
                                    
            
            
                | 25 |  |  | from ..constants import TYPE | 
            
                                                                                                            
                            
            
                                    
            
            
                | 26 |  |  | from ..types import TypeData | 
            
                                                                                                            
                            
            
                                    
            
            
                | 27 |  |  | from ..types import TypeDataAffine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 28 |  |  | from ..types import TypeDirection3D | 
            
                                                                                                            
                            
            
                                    
            
            
                | 29 |  |  | from ..types import TypePath | 
            
                                                                                                            
                            
            
                                    
            
            
                | 30 |  |  | from ..types import TypeQuartetInt | 
            
                                                                                                            
                            
            
                                    
            
            
                | 31 |  |  | from ..types import TypeSlice | 
            
                                                                                                            
                            
            
                                    
            
            
                | 32 |  |  | from ..types import TypeTripletFloat | 
            
                                                                                                            
                            
            
                                    
            
            
                | 33 |  |  | from ..types import TypeTripletInt | 
            
                                                                                                            
                            
            
                                    
            
            
                | 34 |  |  | from ..utils import get_stem | 
            
                                                                                                            
                            
            
                                    
            
            
                | 35 |  |  | from ..utils import guess_external_viewer | 
            
                                                                                                            
                            
            
                                    
            
            
                | 36 |  |  | from ..utils import is_iterable | 
            
                                                                                                            
                            
            
                                    
            
            
                | 37 |  |  | from ..utils import to_tuple | 
            
                                                                                                            
                            
            
                                    
            
            
                | 38 |  |  | from .io import check_uint_to_int | 
            
                                                                                                            
                            
            
                                    
            
            
                | 39 |  |  | from .io import ensure_4d | 
            
                                                                                                            
                            
            
                                    
            
            
                | 40 |  |  | from .io import get_rotation_and_spacing_from_affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 41 |  |  | from .io import get_sitk_metadata_from_ras_affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 42 |  |  | from .io import nib_to_sitk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 43 |  |  | from .io import read_affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 44 |  |  | from .io import read_image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 45 |  |  | from .io import read_shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 46 |  |  | from .io import sitk_to_nib | 
            
                                                                                                            
                            
            
                                    
            
            
                | 47 |  |  | from .io import write_image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 48 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 49 |  |  | PROTECTED_KEYS = DATA, AFFINE, TYPE, PATH, STEM | 
            
                                                                                                            
                            
            
                                    
            
            
                | 50 |  |  | TypeBound = tuple[float, float] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 51 |  |  | TypeBounds = tuple[TypeBound, TypeBound, TypeBound] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 52 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 53 |  |  | deprecation_message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 54 |  |  |     'Setting the image data with the property setter is deprecated. Use the' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 55 |  |  |     ' set_data() method instead' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 56 |  |  | ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 57 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 58 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 59 |  |  | class Image(dict): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 60 |  |  |     r"""TorchIO image. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 61 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 62 |  |  |     For information about medical image orientation, check out `NiBabel docs`_, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 63 |  |  |     the `3D Slicer wiki`_, `Graham Wideman's website`_, `FSL docs`_ or | 
            
                                                                                                            
                            
            
                                    
            
            
                | 64 |  |  |     `SimpleITK docs`_. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 65 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 66 |  |  |     Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 67 |  |  |         path: Path to a file or sequence of paths to files that can be read by | 
            
                                                                                                            
                            
            
                                    
            
            
                | 68 |  |  |             :mod:`SimpleITK` or :mod:`nibabel`, or to a directory containing | 
            
                                                                                                            
                            
            
                                    
            
            
                | 69 |  |  |             DICOM files. If :attr:`tensor` is given, the data in | 
            
                                                                                                            
                            
            
                                    
            
            
                | 70 |  |  |             :attr:`path` will not be read. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 71 |  |  |             If a sequence of paths is given, data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 72 |  |  |             will be concatenated on the channel dimension so spatial | 
            
                                                                                                            
                            
            
                                    
            
            
                | 73 |  |  |             dimensions must match. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 74 |  |  |         type: Type of image, such as :attr:`torchio.INTENSITY` or | 
            
                                                                                                            
                            
            
                                    
            
            
                | 75 |  |  |             :attr:`torchio.LABEL`. This will be used by the transforms to | 
            
                                                                                                            
                            
            
                                    
            
            
                | 76 |  |  |             decide whether to apply an operation, or which interpolation to use | 
            
                                                                                                            
                            
            
                                    
            
            
                | 77 |  |  |             when resampling. For example, `preprocessing`_ and `augmentation`_ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 78 |  |  |             intensity transforms will only be applied to images with type | 
            
                                                                                                            
                            
            
                                    
            
            
                | 79 |  |  |             :attr:`torchio.INTENSITY`. Spatial transforms will be applied to | 
            
                                                                                                            
                            
            
                                    
            
            
                | 80 |  |  |             all types, and nearest neighbor interpolation is always used to | 
            
                                                                                                            
                            
            
                                    
            
            
                | 81 |  |  |             resample images with type :attr:`torchio.LABEL`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 82 |  |  |             The type :attr:`torchio.SAMPLING_MAP` may be used with instances of | 
            
                                                                                                            
                            
            
                                    
            
            
                | 83 |  |  |             :class:`~torchio.data.sampler.weighted.WeightedSampler`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 84 |  |  |         tensor: If :attr:`path` is not given, :attr:`tensor` must be a 4D | 
            
                                                                                                            
                            
            
                                    
            
            
                | 85 |  |  |             :class:`torch.Tensor` or NumPy array with dimensions | 
            
                                                                                                            
                            
            
                                    
            
            
                | 86 |  |  |             :math:`(C, W, H, D)`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 87 |  |  |         affine: :math:`4 \times 4` matrix to convert voxel coordinates to world | 
            
                                                                                                            
                            
            
                                    
            
            
                | 88 |  |  |             coordinates. If ``None``, an identity matrix will be used. See the | 
            
                                                                                                            
                            
            
                                    
            
            
                | 89 |  |  |             `NiBabel docs on coordinates`_ for more information. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 90 |  |  |         check_nans: If ``True``, issues a warning if NaNs are found | 
            
                                                                                                            
                            
            
                                    
            
            
                | 91 |  |  |             in the image. If ``False``, images will not be checked for the | 
            
                                                                                                            
                            
            
                                    
            
            
                | 92 |  |  |             presence of NaNs. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 93 |  |  |         reader: Callable object that takes a path and returns a 4D tensor and a | 
            
                                                                                                            
                            
            
                                    
            
            
                | 94 |  |  |             2D, :math:`4 \times 4` affine matrix. This can be used if your data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 95 |  |  |             is saved in a custom format, such as ``.npy`` (see example below). | 
            
                                                                                                            
                            
            
                                    
            
            
                | 96 |  |  |             If the affine matrix is ``None``, an identity matrix will be used. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 97 |  |  |         **kwargs: Items that will be added to the image dictionary, e.g. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 98 |  |  |             acquisition parameters or image ID. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 99 |  |  |         verify_path: If ``True``, the path will be checked to see if it exists. If | 
            
                                                                                                            
                            
            
                                    
            
            
                | 100 |  |  |             ``False``, the path will not be verified. This is useful when it is | 
            
                                                                                                            
                            
            
                                    
            
            
                | 101 |  |  |             expensive to check the path, e.g., when reading a large dataset from a | 
            
                                                                                                            
                            
            
                                    
            
            
                | 102 |  |  |             mounted drive. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 103 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 104 |  |  |     TorchIO images are `lazy loaders`_, i.e. the data is only loaded from disk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 105 |  |  |     when needed. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 106 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 107 |  |  |     Example: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 108 |  |  |         >>> import torchio as tio | 
            
                                                                                                            
                            
            
                                    
            
            
                | 109 |  |  |         >>> import numpy as np | 
            
                                                                                                            
                            
            
                                    
            
            
                | 110 |  |  |         >>> image = tio.ScalarImage('t1.nii.gz')  # subclass of Image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 111 |  |  |         >>> image  # not loaded yet | 
            
                                                                                                            
                            
            
                                    
            
            
                | 112 |  |  |         ScalarImage(path: t1.nii.gz; type: intensity) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 113 |  |  |         >>> times_two = 2 * image.data  # data is loaded and cached here | 
            
                                                                                                            
                            
            
                                    
            
            
                | 114 |  |  |         >>> image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 115 |  |  |         ScalarImage(shape: (1, 256, 256, 176); spacing: (1.00, 1.00, 1.00); orientation: PIR+; memory: 44.0 MiB; type: intensity) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 116 |  |  |         >>> image.save('doubled_image.nii.gz') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 117 |  |  |         >>> def numpy_reader(path): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 118 |  |  |         ...     data = np.load(path).as_type(np.float32) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 119 |  |  |         ...     affine = np.eye(4) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 120 |  |  |         ...     return data, affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 121 |  |  |         >>> image = tio.ScalarImage('t1.npy', reader=numpy_reader) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 122 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 123 |  |  |     .. _lazy loaders: https://en.wikipedia.org/wiki/Lazy_loading | 
            
                                                                                                            
                            
            
                                    
            
            
                | 124 |  |  |     .. _preprocessing: https://torchio.readthedocs.io/transforms/preprocessing.html#intensity | 
            
                                                                                                            
                            
            
                                    
            
            
                | 125 |  |  |     .. _augmentation: https://torchio.readthedocs.io/transforms/augmentation.html#intensity | 
            
                                                                                                            
                            
            
                                    
            
            
                | 126 |  |  |     .. _NiBabel docs: https://nipy.org/nibabel/image_orientation.html | 
            
                                                                                                            
                            
            
                                    
            
            
                | 127 |  |  |     .. _NiBabel docs on coordinates: https://nipy.org/nibabel/coordinate_systems.html#the-affine-matrix-as-a-transformation-between-spaces | 
            
                                                                                                            
                            
            
                                    
            
            
                | 128 |  |  |     .. _3D Slicer wiki: https://www.slicer.org/wiki/Coordinate_systems | 
            
                                                                                                            
                            
            
                                    
            
            
                | 129 |  |  |     .. _FSL docs: https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/Orientation%20Explained | 
            
                                                                                                            
                            
            
                                    
            
            
                | 130 |  |  |     .. _SimpleITK docs: https://simpleitk.readthedocs.io/en/master/fundamentalConcepts.html | 
            
                                                                                                            
                            
            
                                    
            
            
                | 131 |  |  |     .. _Graham Wideman's website: http://www.grahamwideman.com/gw/brain/orientation/orientterms.htm | 
            
                                                                                                            
                            
            
                                    
            
            
                | 132 |  |  |     """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 133 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 134 |  |  |     def __init__( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 135 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 136 |  |  |         path: TypePath | Sequence[TypePath] | None = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 137 |  |  |         type: str | None = None,  # noqa: A002 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 138 |  |  |         tensor: TypeData | None = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 139 |  |  |         affine: TypeData | None = None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 140 |  |  |         check_nans: bool = False,  # removed by ITK by default | 
            
                                                                                                            
                            
            
                                    
            
            
                | 141 |  |  |         reader: Callable[[TypePath], TypeDataAffine] = read_image, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 142 |  |  |         verify_path: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 143 |  |  |         **kwargs: dict[str, Any], | 
            
                                                                                                            
                            
            
                                    
            
            
                | 144 |  |  |     ): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 145 |  |  |         self.check_nans = check_nans | 
            
                                                                                                            
                            
            
                                    
            
            
                | 146 |  |  |         self.reader = reader | 
            
                                                                                                            
                            
            
                                    
            
            
                | 147 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 148 |  |  |         if type is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 149 |  |  |             warnings.warn( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 150 |  |  |                 'Not specifying the image type is deprecated and will be' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 151 |  |  |                 ' mandatory in the future. You can probably use' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 152 |  |  |                 ' tio.ScalarImage or tio.LabelMap instead', | 
            
                                                                                                            
                            
            
                                    
            
            
                | 153 |  |  |                 FutureWarning, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 154 |  |  |                 stacklevel=2, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 155 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 156 |  |  |             type = INTENSITY  # noqa: A001 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 157 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 158 |  |  |         if path is None and tensor is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 159 |  |  |             raise ValueError('A value for path or tensor must be given') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 160 |  |  |         self._loaded = False | 
            
                                                                                                            
                            
            
                                    
            
            
                | 161 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 162 |  |  |         tensor = self._parse_tensor(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 163 |  |  |         affine = self._parse_affine(affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 164 |  |  |         if tensor is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 165 |  |  |             self.set_data(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 166 |  |  |             self.affine = affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 167 |  |  |             self._loaded = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 168 |  |  |         for key in PROTECTED_KEYS: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 169 |  |  |             if key in kwargs: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 170 |  |  |                 message = f'Key "{key}" is reserved. Use a different one' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 171 |  |  |                 raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 172 |  |  |         if 'channels_last' in kwargs: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 173 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 174 |  |  |                 'The "channels_last" keyword argument is deprecated after' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 175 |  |  |                 ' https://github.com/TorchIO-project/torchio/pull/685 and will be' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 176 |  |  |                 ' removed in the future' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 177 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 178 |  |  |             warnings.warn(message, FutureWarning, stacklevel=2) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 179 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 180 |  |  |         super().__init__(**kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 181 |  |  |         self.path = self._parse_path(path, verify=verify_path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 182 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 183 |  |  |         self[PATH] = '' if self.path is None else str(self.path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 184 |  |  |         self[STEM] = '' if self.path is None else get_stem(self.path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 185 |  |  |         self[TYPE] = type | 
            
                                                                                                            
                            
            
                                    
            
            
                | 186 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 187 |  |  |     def __repr__(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 188 |  |  |         properties = [] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 189 |  |  |         properties.extend( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 190 |  |  |             [ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 191 |  |  |                 f'shape: {self.shape}', | 
            
                                                                                                            
                            
            
                                    
            
            
                | 192 |  |  |                 f'spacing: {self.get_spacing_string()}', | 
            
                                                                                                            
                            
            
                                    
            
            
                | 193 |  |  |                 f'orientation: {"".join(self.orientation)}+', | 
            
                                                                                                            
                            
            
                                    
            
            
                | 194 |  |  |             ] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 195 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 196 |  |  |         if self._loaded: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 197 |  |  |             properties.append(f'dtype: {self.data.type()}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 198 |  |  |             natural = humanize.naturalsize(self.memory, binary=True) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 199 |  |  |             properties.append(f'memory: {natural}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 200 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 201 |  |  |             properties.append(f'path: "{self.path}"') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 202 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 203 |  |  |         properties = '; '.join(properties) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 204 |  |  |         string = f'{self.__class__.__name__}({properties})' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 205 |  |  |         return string | 
            
                                                                                                            
                            
            
                                    
            
            
                | 206 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 207 |  |  |     def __getitem__(self, item): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 208 |  |  |         if isinstance(item, (slice, int, tuple)): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 209 |  |  |             return self._crop_from_slices(item) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 210 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 211 |  |  |         if item in (DATA, AFFINE): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 212 |  |  |             if item not in self: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 213 |  |  |                 self.load() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 214 |  |  |         return super().__getitem__(item) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 215 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 216 |  |  |     def __array__(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 217 |  |  |         return self.data.numpy() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 218 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 219 |  |  |     def __copy__(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 220 |  |  |         kwargs = { | 
            
                                                                                                            
                            
            
                                    
            
            
                | 221 |  |  |             TYPE: self.type, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 222 |  |  |             PATH: self.path, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 223 |  |  |         } | 
            
                                                                                                            
                            
            
                                    
            
            
                | 224 |  |  |         if self._loaded: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 225 |  |  |             kwargs[TENSOR] = self.data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 226 |  |  |             kwargs[AFFINE] = self.affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 227 |  |  |         for key, value in self.items(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 228 |  |  |             if key in PROTECTED_KEYS: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 229 |  |  |                 continue | 
            
                                                                                                            
                            
            
                                    
            
            
                | 230 |  |  |             kwargs[key] = value  # should I copy? deepcopy? | 
            
                                                                                                            
                            
            
                                    
            
            
                | 231 |  |  |         new_image_class = type(self) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 232 |  |  |         new_image = new_image_class( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 233 |  |  |             check_nans=self.check_nans, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 234 |  |  |             reader=self.reader, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 235 |  |  |             **kwargs, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 236 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 237 |  |  |         return new_image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 238 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 239 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 240 |  |  |     def data(self) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 241 |  |  |         """Tensor data (same as :class:`Image.tensor`).""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 242 |  |  |         return self[DATA] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 243 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 244 |  |  |     @data.setter  # type: ignore[misc] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 245 |  |  |     @deprecated(version='0.18.16', reason=deprecation_message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 246 |  |  |     def data(self, tensor: TypeData): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 247 |  |  |         self.set_data(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 248 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 249 |  |  |     def set_data(self, tensor: TypeData): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 250 |  |  |         """Store a 4D tensor in the :attr:`data` key and attribute. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 251 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 252 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 253 |  |  |             tensor: 4D tensor with dimensions :math:`(C, W, H, D)`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 254 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 255 |  |  |         self[DATA] = self._parse_tensor(tensor, none_ok=False) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 256 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 257 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 258 |  |  |     def tensor(self) -> torch.Tensor: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 259 |  |  |         """Tensor data (same as :class:`Image.data`).""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 260 |  |  |         return self.data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 261 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 262 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 263 |  |  |     def affine(self) -> np.ndarray: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 264 |  |  |         """Affine matrix to transform voxel indices into world coordinates.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 265 |  |  |         # If path is a dir (probably DICOM), just load the data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 266 |  |  |         # Same if it's a list of paths (used to create a 4D image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 267 |  |  |         # Finally, if we use a custom reader, SimpleITK probably won't be able | 
            
                                                                                                            
                            
            
                                    
            
            
                | 268 |  |  |         # to read the metadata, so we resort to loading everything into memory | 
            
                                                                                                            
                            
            
                                    
            
            
                | 269 |  |  |         is_custom_reader = self.reader is not read_image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 270 |  |  |         if self._loaded or self._is_dir() or self._is_multipath() or is_custom_reader: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 271 |  |  |             affine = self[AFFINE] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 272 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 273 |  |  |             assert self.path is not None | 
            
                                                                                                            
                            
            
                                    
            
            
                | 274 |  |  |             assert isinstance(self.path, (str, Path)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 275 |  |  |             affine = read_affine(self.path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 276 |  |  |         return affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 277 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 278 |  |  |     @affine.setter | 
            
                                                                                                            
                            
            
                                    
            
            
                | 279 |  |  |     def affine(self, matrix): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 280 |  |  |         self[AFFINE] = self._parse_affine(matrix) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 281 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 282 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 283 |  |  |     def type(self) -> str:  # noqa: A003 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 284 |  |  |         return self[TYPE] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 285 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 286 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 287 |  |  |     def shape(self) -> TypeQuartetInt: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 288 |  |  |         """Tensor shape as :math:`(C, W, H, D)`.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 289 |  |  |         custom_reader = self.reader is not read_image | 
            
                                                                                                            
                            
            
                                    
            
            
                | 290 |  |  |         multipath = self._is_multipath() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 291 |  |  |         if isinstance(self.path, Path): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 292 |  |  |             is_dir = self.path.is_dir() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 293 |  |  |         shape: TypeQuartetInt | 
            
                                                                                                            
                            
            
                                    
            
            
                | 294 |  |  |         if self._loaded or custom_reader or multipath or is_dir: | 
                            
                    |  |  |  | 
                                                                                        
                                                                                     | 
            
                                                                                                            
                            
            
                                    
            
            
                | 295 |  |  |             channels, si, sj, sk = self.data.shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 296 |  |  |             shape = channels, si, sj, sk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 297 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 298 |  |  |             assert isinstance(self.path, (str, Path)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 299 |  |  |             shape = read_shape(self.path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 300 |  |  |         return shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 301 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 302 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 303 |  |  |     def spatial_shape(self) -> TypeTripletInt: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 304 |  |  |         """Tensor spatial shape as :math:`(W, H, D)`.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 305 |  |  |         return self.shape[1:] | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 306 |  |  |  | 
            
                                                                        
                            
            
                                    
            
            
                | 307 |  |  |     def check_is_2d(self) -> None: | 
            
                                                                        
                            
            
                                    
            
            
                | 308 |  |  |         if not self.is_2d(): | 
            
                                                                        
                            
            
                                    
            
            
                | 309 |  |  |             message = f'Image is not 2D. Spatial shape: {self.spatial_shape}' | 
            
                                                                        
                            
            
                                    
            
            
                | 310 |  |  |             raise RuntimeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 311 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 312 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 313 |  |  |     def height(self) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 314 |  |  |         """Image height, if 2D.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 315 |  |  |         self.check_is_2d() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 316 |  |  |         return self.spatial_shape[1] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 317 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 318 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 319 |  |  |     def width(self) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 320 |  |  |         """Image width, if 2D.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 321 |  |  |         self.check_is_2d() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 322 |  |  |         return self.spatial_shape[0] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 323 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 324 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 325 |  |  |     def orientation(self) -> tuple[str, str, str]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 326 |  |  |         """Orientation codes.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 327 |  |  |         return nib.aff2axcodes(self.affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 328 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 329 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 330 |  |  |     def direction(self) -> TypeDirection3D: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 331 |  |  |         _, _, direction = get_sitk_metadata_from_ras_affine( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 332 |  |  |             self.affine, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 333 |  |  |             lps=False, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 334 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 335 |  |  |         return direction  # type: ignore[return-value] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 336 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 337 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 338 |  |  |     def spacing(self) -> tuple[float, float, float]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 339 |  |  |         """Voxel spacing in mm.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 340 |  |  |         _, spacing = get_rotation_and_spacing_from_affine(self.affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 341 |  |  |         sx, sy, sz = spacing | 
            
                                                                                                            
                            
            
                                    
            
            
                | 342 |  |  |         return sx, sy, sz | 
            
                                                                                                            
                            
            
                                    
            
            
                | 343 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 344 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 345 |  |  |     def origin(self) -> tuple[float, float, float]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 346 |  |  |         """Center of first voxel in array, in mm.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 347 |  |  |         ox, oy, oz = self.affine[:3, 3] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 348 |  |  |         return ox, oy, oz | 
            
                                                                                                            
                            
            
                                    
            
            
                | 349 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 350 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 351 |  |  |     def itemsize(self): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 352 |  |  |         """Element size of the data type.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 353 |  |  |         return self.data.element_size() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 354 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 355 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 356 |  |  |     def memory(self) -> float: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 357 |  |  |         """Number of Bytes that the tensor takes in the RAM.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 358 |  |  |         return np.prod(self.shape) * self.itemsize | 
            
                                                                                                            
                            
            
                                    
            
            
                | 359 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 360 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 361 |  |  |     def bounds(self) -> np.ndarray: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 362 |  |  |         """Position of centers of voxels in smallest and largest indices.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 363 |  |  |         ini = 0, 0, 0 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 364 |  |  |         fin = np.array(self.spatial_shape) - 1 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 365 |  |  |         point_ini = apply_affine(self.affine, ini) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 366 |  |  |         point_fin = apply_affine(self.affine, fin) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 367 |  |  |         return np.array((point_ini, point_fin)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 368 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 369 |  |  |     @property | 
            
                                                                                                            
                            
            
                                    
            
            
                | 370 |  |  |     def num_channels(self) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 371 |  |  |         """Get the number of channels in the associated 4D tensor.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 372 |  |  |         return len(self.data) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 373 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 374 |  |  |     def axis_name_to_index(self, axis: str) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 375 |  |  |         """Convert an axis name to an axis index. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 376 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 377 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 378 |  |  |             axis: Possible inputs are ``'Left'``, ``'Right'``, ``'Anterior'``, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 379 |  |  |                 ``'Posterior'``, ``'Inferior'``, ``'Superior'``. Lower-case | 
            
                                                                                                            
                            
            
                                    
            
            
                | 380 |  |  |                 versions and first letters are also valid, as only the first | 
            
                                                                                                            
                            
            
                                    
            
            
                | 381 |  |  |                 letter will be used. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 382 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 383 |  |  |         .. note:: If you are working with animals, you should probably use | 
            
                                                                                                            
                            
            
                                    
            
            
                | 384 |  |  |             ``'Superior'``, ``'Inferior'``, ``'Anterior'`` and ``'Posterior'`` | 
            
                                                                                                            
                            
            
                                    
            
            
                | 385 |  |  |             for ``'Dorsal'``, ``'Ventral'``, ``'Rostral'`` and ``'Caudal'``, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 386 |  |  |             respectively. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 387 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 388 |  |  |         .. note:: If your images are 2D, you can use ``'Top'``, ``'Bottom'``, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 389 |  |  |             ``'Left'`` and ``'Right'``. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 390 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 391 |  |  |         # Top and bottom are used for the vertical 2D axis as the use of | 
            
                                                                                                            
                            
            
                                    
            
            
                | 392 |  |  |         # Height vs Horizontal might be ambiguous | 
            
                                                                                                            
                            
            
                                    
            
            
                | 393 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 394 |  |  |         if not isinstance(axis, str): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 395 |  |  |             raise ValueError('Axis must be a string') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 396 |  |  |         axis = axis[0].upper() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 397 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 398 |  |  |         # Generally, TorchIO tensors are (C, W, H, D) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 399 |  |  |         if axis in 'TB':  # Top, Bottom | 
            
                                                                                                            
                            
            
                                    
            
            
                | 400 |  |  |             return -2 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 401 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 402 |  |  |             try: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 403 |  |  |                 index = self.orientation.index(axis) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 404 |  |  |             except ValueError: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 405 |  |  |                 index = self.orientation.index(self.flip_axis(axis)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 406 |  |  |             # Return negative indices so that it does not matter whether we | 
            
                                                                                                            
                            
            
                                    
            
            
                | 407 |  |  |             # refer to spatial dimensions or not | 
            
                                                                                                            
                            
            
                                    
            
            
                | 408 |  |  |             index = -3 + index | 
            
                                                                                                            
                            
            
                                    
            
            
                | 409 |  |  |             return index | 
            
                                                                                                            
                            
            
                                    
            
            
                | 410 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 411 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 412 |  |  |     def flip_axis(axis: str) -> str: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 413 |  |  |         """Return the opposite axis label. For example, ``'L'`` -> ``'R'``. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 414 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 415 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 416 |  |  |             axis: Axis label, such as ``'L'`` or ``'left'``. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 417 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 418 |  |  |         labels = 'LRPAISTBDV' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 419 |  |  |         first = labels[::2] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 420 |  |  |         last = labels[1::2] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 421 |  |  |         flip_dict = dict(zip(first + last, last + first)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 422 |  |  |         axis = axis[0].upper() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 423 |  |  |         flipped_axis = flip_dict.get(axis) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 424 |  |  |         if flipped_axis is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 425 |  |  |             values = ', '.join(labels) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 426 |  |  |             message = f'Axis not understood. Please use one of: {values}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 427 |  |  |             raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 428 |  |  |         return flipped_axis | 
            
                                                                                                            
                            
            
                                    
            
            
                | 429 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 430 |  |  |     def get_spacing_string(self) -> str: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 431 |  |  |         strings = [f'{n:.2f}' for n in self.spacing] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 432 |  |  |         string = f'({", ".join(strings)})' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 433 |  |  |         return string | 
            
                                                                                                            
                            
            
                                    
            
            
                | 434 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 435 |  |  |     def get_bounds(self) -> TypeBounds: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 436 |  |  |         """Get minimum and maximum world coordinates occupied by the image.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 437 |  |  |         first_index = 3 * (-0.5,) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 438 |  |  |         last_index = np.array(self.spatial_shape) - 0.5 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 439 |  |  |         first_point = apply_affine(self.affine, first_index) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 440 |  |  |         last_point = apply_affine(self.affine, last_index) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 441 |  |  |         array = np.array((first_point, last_point)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 442 |  |  |         bounds_x, bounds_y, bounds_z = array.T.tolist()  # type: ignore[misc] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 443 |  |  |         return bounds_x, bounds_y, bounds_z  # type: ignore[return-value] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 444 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 445 |  |  |     def _parse_single_path( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 446 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 447 |  |  |         path: TypePath, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 448 |  |  |         *, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 449 |  |  |         verify: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 450 |  |  |     ) -> Path: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 451 |  |  |         if isinstance(path, (torch.Tensor, np.ndarray)): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 452 |  |  |             class_name = self.__class__.__name__ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 453 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 454 |  |  |                 'Expected type str or Path but found a tensor/array. Instead of' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 455 |  |  |                 f' {class_name}(your_tensor),' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 456 |  |  |                 f' use {class_name}(tensor=your_tensor).' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 457 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 458 |  |  |             raise TypeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 459 |  |  |         try: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 460 |  |  |             path = Path(path).expanduser() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 461 |  |  |         except TypeError as err: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 462 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 463 |  |  |                 f'Expected type str or Path but found an object with type' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 464 |  |  |                 f' {type(path)} instead' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 465 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 466 |  |  |             raise TypeError(message) from err | 
            
                                                                                                            
                            
            
                                    
            
            
                | 467 |  |  |         except RuntimeError as err: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 468 |  |  |             message = f'Conversion to path not possible for variable: {path}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 469 |  |  |             raise RuntimeError(message) from err | 
            
                                                                                                            
                            
            
                                    
            
            
                | 470 |  |  |         if not verify: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 471 |  |  |             return path | 
            
                                                                                                            
                            
            
                                    
            
            
                | 472 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 473 |  |  |         if not (path.is_file() or path.is_dir()):  # might be a dir with DICOM | 
            
                                                                                                            
                            
            
                                    
            
            
                | 474 |  |  |             raise FileNotFoundError(f'File not found: "{path}"') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 475 |  |  |         return path | 
            
                                                                                                            
                            
            
                                    
            
            
                | 476 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 477 |  |  |     def _parse_path( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 478 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 479 |  |  |         path: TypePath | Sequence[TypePath] | None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 480 |  |  |         *, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 481 |  |  |         verify: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 482 |  |  |     ) -> Path | list[Path] | None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 483 |  |  |         if path is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 484 |  |  |             return None | 
            
                                                                                                            
                            
            
                                    
            
            
                | 485 |  |  |         elif isinstance(path, dict): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 486 |  |  |             # https://github.com/TorchIO-project/torchio/pull/838 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 487 |  |  |             raise TypeError('The path argument cannot be a dictionary') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 488 |  |  |         elif self._is_paths_sequence(path): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 489 |  |  |             return [self._parse_single_path(p, verify=verify) for p in path]  # type: ignore[union-attr] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 490 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 491 |  |  |             return self._parse_single_path(path, verify=verify)  # type: ignore[arg-type] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 492 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 493 |  |  |     def _parse_tensor( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 494 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 495 |  |  |         tensor: TypeData | None, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 496 |  |  |         none_ok: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 497 |  |  |     ) -> torch.Tensor | None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 498 |  |  |         if tensor is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 499 |  |  |             if none_ok: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 500 |  |  |                 return None | 
            
                                                                                                            
                            
            
                                    
            
            
                | 501 |  |  |             else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 502 |  |  |                 raise RuntimeError('Input tensor cannot be None') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 503 |  |  |         if isinstance(tensor, np.ndarray): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 504 |  |  |             tensor = check_uint_to_int(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 505 |  |  |             tensor = torch.as_tensor(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 506 |  |  |         elif not isinstance(tensor, torch.Tensor): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 507 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 508 |  |  |                 'Input tensor must be a PyTorch tensor or NumPy array,' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 509 |  |  |                 f' but type "{type(tensor)}" was found' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 510 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 511 |  |  |             raise TypeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 512 |  |  |         ndim = tensor.ndim | 
            
                                                                                                            
                            
            
                                    
            
            
                | 513 |  |  |         if ndim != 4: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 514 |  |  |             raise ValueError(f'Input tensor must be 4D, but it is {ndim}D') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 515 |  |  |         if tensor.dtype == torch.bool: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 516 |  |  |             tensor = tensor.to(torch.uint8) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 517 |  |  |         if self.check_nans and torch.isnan(tensor).any(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 518 |  |  |             warnings.warn('NaNs found in tensor', RuntimeWarning, stacklevel=2) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 519 |  |  |         return tensor | 
            
                                                                                                            
                            
            
                                    
            
            
                | 520 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 521 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 522 |  |  |     def _parse_tensor_shape(tensor: torch.Tensor) -> TypeData: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 523 |  |  |         return ensure_4d(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 524 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 525 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 526 |  |  |     def _parse_affine(affine: TypeData | None) -> np.ndarray: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 527 |  |  |         if affine is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 528 |  |  |             return np.eye(4) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 529 |  |  |         if isinstance(affine, torch.Tensor): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 530 |  |  |             affine = affine.numpy() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 531 |  |  |         if not isinstance(affine, np.ndarray): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 532 |  |  |             bad_type = type(affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 533 |  |  |             raise TypeError(f'Affine must be a NumPy array, not {bad_type}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 534 |  |  |         if affine.shape != (4, 4): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 535 |  |  |             bad_shape = affine.shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 536 |  |  |             raise ValueError(f'Affine shape must be (4, 4), not {bad_shape}') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 537 |  |  |         return affine.astype(np.float64) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 538 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 539 |  |  |     @staticmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 540 |  |  |     def _is_paths_sequence(path: TypePath | Sequence[TypePath] | None) -> bool: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 541 |  |  |         is_not_string = not isinstance(path, str) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 542 |  |  |         return is_not_string and is_iterable(path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 543 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 544 |  |  |     def _is_multipath(self) -> bool: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 545 |  |  |         return self._is_paths_sequence(self.path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 546 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 547 |  |  |     def _is_dir(self) -> bool: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 548 |  |  |         is_sequence = self._is_multipath() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 549 |  |  |         if is_sequence: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 550 |  |  |             return False | 
            
                                                                                                            
                            
            
                                    
            
            
                | 551 |  |  |         elif self.path is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 552 |  |  |             return False | 
            
                                                                                                            
                            
            
                                    
            
            
                | 553 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 554 |  |  |             assert isinstance(self.path, Path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 555 |  |  |             return self.path.is_dir() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 556 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 557 |  |  |     def load(self) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 558 |  |  |         r"""Load the image from disk. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 559 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 560 |  |  |         Returns: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 561 |  |  |             Tuple containing a 4D tensor of size :math:`(C, W, H, D)` and a 2D | 
            
                                                                                                            
                            
            
                                    
            
            
                | 562 |  |  |             :math:`4 \times 4` affine matrix to convert voxel indices to world | 
            
                                                                                                            
                            
            
                                    
            
            
                | 563 |  |  |             coordinates. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 564 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 565 |  |  |         if self._loaded: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 566 |  |  |             return | 
            
                                                                                                            
                            
            
                                    
            
            
                | 567 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 568 |  |  |         paths: list[Path] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 569 |  |  |         if self._is_multipath(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 570 |  |  |             paths = self.path  # type: ignore[assignment] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 571 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 572 |  |  |             paths = [self.path]  # type: ignore[list-item] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 573 |  |  |         tensor, affine = self.read_and_check(paths[0]) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 574 |  |  |         tensors = [tensor] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 575 |  |  |         for path in paths[1:]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 576 |  |  |             new_tensor, new_affine = self.read_and_check(path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 577 |  |  |             if not np.array_equal(affine, new_affine): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 578 |  |  |                 message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 579 |  |  |                     'Files have different affine matrices.' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 580 |  |  |                     f'\nMatrix of {paths[0]}:' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 581 |  |  |                     f'\n{affine}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 582 |  |  |                     f'\nMatrix of {path}:' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 583 |  |  |                     f'\n{new_affine}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 584 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 585 |  |  |                 warnings.warn(message, RuntimeWarning, stacklevel=2) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 586 |  |  |             if not tensor.shape[1:] == new_tensor.shape[1:]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 587 |  |  |                 message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 588 |  |  |                     f'Files shape do not match, found {tensor.shape}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 589 |  |  |                     f'and {new_tensor.shape}' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 590 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 591 |  |  |                 RuntimeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 592 |  |  |             tensors.append(new_tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 593 |  |  |         tensor = torch.cat(tensors) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 594 |  |  |         self.set_data(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 595 |  |  |         self.affine = affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 596 |  |  |         self._loaded = True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 597 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 598 |  |  |     def unload(self) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 599 |  |  |         """Unload the image from memory. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 600 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 601 |  |  |         Raises: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 602 |  |  |             RuntimeError: If the images has not been loaded yet or if no path | 
            
                                                                                                            
                            
            
                                    
            
            
                | 603 |  |  |                 is available. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 604 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 605 |  |  |         if not self._loaded: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 606 |  |  |             message = 'Image cannot be unloaded as it has not been loaded yet' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 607 |  |  |             raise RuntimeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 608 |  |  |         if self.path is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 609 |  |  |             message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 610 |  |  |                 'Cannot unload image as no path is available' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 611 |  |  |                 ' from where the image could be loaded again' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 612 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 613 |  |  |             raise RuntimeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 614 |  |  |         self[DATA] = None | 
            
                                                                                                            
                            
            
                                    
            
            
                | 615 |  |  |         self[AFFINE] = None | 
            
                                                                                                            
                            
            
                                    
            
            
                | 616 |  |  |         self._loaded = False | 
            
                                                                                                            
                            
            
                                    
            
            
                | 617 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 618 |  |  |     def read_and_check(self, path: TypePath) -> TypeDataAffine: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 619 |  |  |         tensor, affine = self.reader(path) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 620 |  |  |         # Make sure the data type is compatible with PyTorch | 
            
                                                                                                            
                            
            
                                    
            
            
                | 621 |  |  |         if self.reader is not read_image and isinstance(tensor, np.ndarray): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 622 |  |  |             tensor = check_uint_to_int(tensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 623 |  |  |         tensor = self._parse_tensor_shape(tensor)  # type: ignore[assignment] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 624 |  |  |         tensor = self._parse_tensor(tensor)  # type: ignore[assignment] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 625 |  |  |         affine = self._parse_affine(affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 626 |  |  |         if self.check_nans and torch.isnan(tensor).any(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 627 |  |  |             warnings.warn( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 628 |  |  |                 f'NaNs found in file "{path}"', | 
            
                                                                                                            
                            
            
                                    
            
            
                | 629 |  |  |                 RuntimeWarning, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 630 |  |  |                 stacklevel=2, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 631 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 632 |  |  |         return tensor, affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 633 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 634 |  |  |     def save(self, path: TypePath, squeeze: bool | None = None) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 635 |  |  |         """Save image to disk. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 636 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 637 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 638 |  |  |             path: String or instance of :class:`pathlib.Path`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 639 |  |  |             squeeze: Whether to remove singleton dimensions before saving. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 640 |  |  |                 If ``None``, the array will be squeezed if the output format is | 
            
                                                                                                            
                            
            
                                    
            
            
                | 641 |  |  |                 JP(E)G, PNG, BMP or TIF(F). | 
            
                                                                                                            
                            
            
                                    
            
            
                | 642 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 643 |  |  |         write_image( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 644 |  |  |             self.data, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 645 |  |  |             self.affine, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 646 |  |  |             path, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 647 |  |  |             squeeze=squeeze, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 648 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 649 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 650 |  |  |     def is_2d(self) -> bool: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 651 |  |  |         return self.shape[-1] == 1 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 652 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 653 |  |  |     def numpy(self) -> np.ndarray: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 654 |  |  |         """Get a NumPy array containing the image data.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 655 |  |  |         return np.asarray(self) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 656 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 657 |  |  |     def as_sitk(self, **kwargs) -> sitk.Image: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 658 |  |  |         """Get the image as an instance of :class:`sitk.Image`.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 659 |  |  |         return nib_to_sitk(self.data, self.affine, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 660 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 661 |  |  |     @classmethod | 
            
                                                                                                            
                            
            
                                    
            
            
                | 662 |  |  |     def from_sitk(cls, sitk_image): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 663 |  |  |         """Instantiate a new TorchIO image from a :class:`sitk.Image`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 664 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 665 |  |  |         Example: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 666 |  |  |             >>> import torchio as tio | 
            
                                                                                                            
                            
            
                                    
            
            
                | 667 |  |  |             >>> import SimpleITK as sitk | 
            
                                                                                                            
                            
            
                                    
            
            
                | 668 |  |  |             >>> sitk_image = sitk.Image(20, 30, 40, sitk.sitkUInt16) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 669 |  |  |             >>> tio.LabelMap.from_sitk(sitk_image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 670 |  |  |             LabelMap(shape: (1, 20, 30, 40); spacing: (1.00, 1.00, 1.00); orientation: LPS+; memory: 93.8 KiB; dtype: torch.IntTensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 671 |  |  |             >>> sitk_image = sitk.Image((224, 224), sitk.sitkVectorFloat32, 3) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 672 |  |  |             >>> tio.ScalarImage.from_sitk(sitk_image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 673 |  |  |             ScalarImage(shape: (3, 224, 224, 1); spacing: (1.00, 1.00, 1.00); orientation: LPS+; memory: 588.0 KiB; dtype: torch.FloatTensor) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 674 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 675 |  |  |         tensor, affine = sitk_to_nib(sitk_image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 676 |  |  |         return cls(tensor=tensor, affine=affine) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 677 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 678 |  |  |     def as_pil(self, transpose=True): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 679 |  |  |         """Get the image as an instance of :class:`PIL.Image`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 680 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 681 |  |  |         .. note:: Values will be clamped to 0-255 and cast to uint8. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 682 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 683 |  |  |         .. note:: To use this method, Pillow needs to be installed: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 684 |  |  |             ``pip install Pillow``. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 685 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 686 |  |  |         try: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 687 |  |  |             from PIL import Image as ImagePIL | 
            
                                                                                                            
                            
            
                                    
            
            
                | 688 |  |  |         except ModuleNotFoundError as e: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 689 |  |  |             message = 'Please install Pillow to use Image.as_pil(): pip install Pillow' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 690 |  |  |             raise RuntimeError(message) from e | 
            
                                                                                                            
                            
            
                                    
            
            
                | 691 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 692 |  |  |         self.check_is_2d() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 693 |  |  |         tensor = self.data | 
            
                                                                                                            
                            
            
                                    
            
            
                | 694 |  |  |         if len(tensor) not in (1, 3, 4): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 695 |  |  |             raise NotImplementedError( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 696 |  |  |                 'Only 1, 3 or 4 channels are supported for conversion to Pillow image' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 697 |  |  |             ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 698 |  |  |         if len(tensor) == 1: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 699 |  |  |             tensor = torch.cat(3 * [tensor]) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 700 |  |  |         if transpose: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 701 |  |  |             tensor = tensor.permute(3, 2, 1, 0) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 702 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 703 |  |  |             tensor = tensor.permute(3, 1, 2, 0) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 704 |  |  |         array = tensor.clamp(0, 255).numpy()[0] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 705 |  |  |         return ImagePIL.fromarray(array.astype(np.uint8)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 706 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 707 |  |  |     def to_gif( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 708 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 709 |  |  |         axis: int, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 710 |  |  |         duration: float,  # of full gif | 
            
                                                                                                            
                            
            
                                    
            
            
                | 711 |  |  |         output_path: TypePath, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 712 |  |  |         loop: int = 0, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 713 |  |  |         rescale: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 714 |  |  |         optimize: bool = True, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 715 |  |  |         reverse: bool = False, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 716 |  |  |     ) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 717 |  |  |         """Save an animated GIF of the image. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 718 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 719 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 720 |  |  |             axis: Spatial axis (0, 1 or 2). | 
            
                                                                                                            
                            
            
                                    
            
            
                | 721 |  |  |             duration: Duration of the full animation in seconds. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 722 |  |  |             output_path: Path to the output GIF file. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 723 |  |  |             loop: Number of times the GIF should loop. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 724 |  |  |                 ``0`` means that it will loop forever. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 725 |  |  |             rescale: Use :class:`~torchio.transforms.preprocessing.intensity.rescale.RescaleIntensity` | 
            
                                                                                                            
                            
            
                                    
            
            
                | 726 |  |  |                 to rescale the intensity values to :math:`[0, 255]`. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 727 |  |  |             optimize: If ``True``, attempt to compress the palette by | 
            
                                                                                                            
                            
            
                                    
            
            
                | 728 |  |  |                 eliminating unused colors. This is only useful if the palette | 
            
                                                                                                            
                            
            
                                    
            
            
                | 729 |  |  |                 can be compressed to the next smaller power of 2 elements. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 730 |  |  |             reverse: Reverse the temporal order of frames. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 731 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 732 |  |  |         from ..visualization import make_gif  # avoid circular import | 
            
                                                                                                            
                            
            
                                    
            
            
                | 733 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 734 |  |  |         make_gif( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 735 |  |  |             self.data, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 736 |  |  |             axis, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 737 |  |  |             duration, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 738 |  |  |             output_path, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 739 |  |  |             loop=loop, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 740 |  |  |             rescale=rescale, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 741 |  |  |             optimize=optimize, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 742 |  |  |             reverse=reverse, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 743 |  |  |         ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 744 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 745 |  |  |     def get_center(self, lps: bool = False) -> TypeTripletFloat: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 746 |  |  |         """Get image center in RAS+ or LPS+ coordinates. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 747 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 748 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 749 |  |  |             lps: If ``True``, the coordinates will be in LPS+ orientation, i.e. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 750 |  |  |                 the first dimension grows towards the left, etc. Otherwise, the | 
            
                                                                                                            
                            
            
                                    
            
            
                | 751 |  |  |                 coordinates will be in RAS+ orientation. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 752 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 753 |  |  |         size = np.array(self.spatial_shape) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 754 |  |  |         center_index = (size - 1) / 2 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 755 |  |  |         r, a, s = apply_affine(self.affine, center_index) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 756 |  |  |         if lps: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 757 |  |  |             return (-r, -a, s) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 758 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 759 |  |  |             return (r, a, s) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 760 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 761 |  |  |     def set_check_nans(self, check_nans: bool) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 762 |  |  |         self.check_nans = check_nans | 
            
                                                                                                            
                            
            
                                    
            
            
                | 763 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 764 |  |  |     def plot(self, **kwargs) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 765 |  |  |         """Plot image.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 766 |  |  |         if self.is_2d(): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 767 |  |  |             self.as_pil().show() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 768 |  |  |         else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 769 |  |  |             from ..visualization import plot_volume  # avoid circular import | 
            
                                                                                                            
                            
            
                                    
            
            
                | 770 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 771 |  |  |             plot_volume(self, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 772 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 773 |  |  |     def show(self, viewer_path: TypePath | None = None) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 774 |  |  |         """Open the image using external software. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 775 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 776 |  |  |         Args: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 777 |  |  |             viewer_path: Path to the application used to view the image. If | 
            
                                                                                                            
                            
            
                                    
            
            
                | 778 |  |  |                 ``None``, the value of the environment variable | 
            
                                                                                                            
                            
            
                                    
            
            
                | 779 |  |  |                 ``SITK_SHOW_COMMAND`` will be used. If this variable is also | 
            
                                                                                                            
                            
            
                                    
            
            
                | 780 |  |  |                 not set, TorchIO will try to guess the location of | 
            
                                                                                                            
                            
            
                                    
            
            
                | 781 |  |  |                 `ITK-SNAP <http://www.itksnap.org/pmwiki/pmwiki.php>`_ and | 
            
                                                                                                            
                            
            
                                    
            
            
                | 782 |  |  |                 `3D Slicer <https://www.slicer.org/>`_. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 783 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 784 |  |  |         Raises: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 785 |  |  |             RuntimeError: If the viewer is not found. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 786 |  |  |         """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 787 |  |  |         sitk_image = self.as_sitk() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 788 |  |  |         image_viewer = sitk.ImageViewer() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 789 |  |  |         # This is so that 3D Slicer creates segmentation nodes from label maps | 
            
                                                                                                            
                            
            
                                    
            
            
                | 790 |  |  |         if self.__class__.__name__ == 'LabelMap': | 
            
                                                                                                            
                            
            
                                    
            
            
                | 791 |  |  |             image_viewer.SetFileExtension('.seg.nrrd') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 792 |  |  |         if viewer_path is not None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 793 |  |  |             image_viewer.SetApplication(str(viewer_path)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 794 |  |  |         try: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 795 |  |  |             image_viewer.Execute(sitk_image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 796 |  |  |         except RuntimeError as e: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 797 |  |  |             viewer_path = guess_external_viewer() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 798 |  |  |             if viewer_path is None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 799 |  |  |                 message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 800 |  |  |                     'No external viewer has been found. Please set the' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 801 |  |  |                     ' environment variable SITK_SHOW_COMMAND to a viewer of' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 802 |  |  |                     ' your choice' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 803 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 804 |  |  |                 raise RuntimeError(message) from e | 
            
                                                                                                            
                            
            
                                    
            
            
                | 805 |  |  |             image_viewer.SetApplication(str(viewer_path)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 806 |  |  |             image_viewer.Execute(sitk_image) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 807 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 808 |  |  |     def _crop_from_slices( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 809 |  |  |         self, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 810 |  |  |         slices: TypeSlice | tuple[TypeSlice, ...], | 
            
                                                                                                            
                            
            
                                    
            
            
                | 811 |  |  |     ) -> Image: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 812 |  |  |         from ..transforms import Crop | 
            
                                                                                                            
                            
            
                                    
            
            
                | 813 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 814 |  |  |         slices_tuple = to_tuple(slices)  # type: ignore[assignment] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 815 |  |  |         cropping: list[int] = [] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 816 |  |  |         for dim, slice_ in enumerate(slices_tuple): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 817 |  |  |             if isinstance(slice_, slice): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 818 |  |  |                 pass | 
            
                                                                                                            
                            
            
                                    
            
            
                | 819 |  |  |             elif slice_ is Ellipsis: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 820 |  |  |                 message = 'Ellipsis slicing is not supported yet' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 821 |  |  |                 raise NotImplementedError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 822 |  |  |             elif isinstance(slice_, int): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 823 |  |  |                 slice_ = slice(slice_, slice_ + 1)  # type: ignore[assignment] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 824 |  |  |             else: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 825 |  |  |                 message = f'Slice type not understood: "{type(slice_)}"' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 826 |  |  |                 raise TypeError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 827 |  |  |             shape_dim = self.spatial_shape[dim] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 828 |  |  |             assert isinstance(slice_, slice) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 829 |  |  |             start, stop, step = slice_.indices(shape_dim) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 830 |  |  |             if step != 1: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 831 |  |  |                 message = ( | 
            
                                                                                                            
                            
            
                                    
            
            
                | 832 |  |  |                     'Slicing with steps different from 1 is not supported yet.' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 833 |  |  |                     ' Use the Crop transform instead' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 834 |  |  |                 ) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 835 |  |  |                 raise ValueError(message) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 836 |  |  |             crop_ini = start | 
            
                                                                                                            
                            
            
                                    
            
            
                | 837 |  |  |             crop_fin = shape_dim - stop | 
            
                                                                                                            
                            
            
                                    
            
            
                | 838 |  |  |             cropping.extend([crop_ini, crop_fin]) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 839 |  |  |         while dim < 2: | 
                            
                    |  |  |  | 
                                                                                        
                                                                                     | 
            
                                                                                                            
                            
            
                                    
            
            
                | 840 |  |  |             cropping.extend([0, 0]) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 841 |  |  |             dim += 1 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 842 |  |  |         w_ini, w_fin, h_ini, h_fin, d_ini, d_fin = cropping | 
            
                                                                                                            
                            
            
                                    
            
            
                | 843 |  |  |         cropping_arg = w_ini, w_fin, h_ini, h_fin, d_ini, d_fin  # making mypy happy | 
            
                                                                                                            
                            
            
                                    
            
            
                | 844 |  |  |         return Crop(cropping_arg)(self)  # type: ignore[return-value] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 845 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 846 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 847 |  |  | class ScalarImage(Image): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 848 |  |  |     """Image whose pixel values represent scalars. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 849 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 850 |  |  |     Example: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 851 |  |  |         >>> import torch | 
            
                                                                                                            
                            
            
                                    
            
            
                | 852 |  |  |         >>> import torchio as tio | 
            
                                                                                                            
                            
            
                                    
            
            
                | 853 |  |  |         >>> # Loading from a file | 
            
                                                                                                            
                            
            
                                    
            
            
                | 854 |  |  |         >>> t1_image = tio.ScalarImage('t1.nii.gz') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 855 |  |  |         >>> dmri = tio.ScalarImage(tensor=torch.rand(32, 128, 128, 88)) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 856 |  |  |         >>> image = tio.ScalarImage('safe_image.nrrd', check_nans=False) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 857 |  |  |         >>> data, affine = image.data, image.affine | 
            
                                                                                                            
                            
            
                                    
            
            
                | 858 |  |  |         >>> affine.shape | 
            
                                                                                                            
                            
            
                                    
            
            
                | 859 |  |  |         (4, 4) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 860 |  |  |         >>> image.data is image[tio.DATA] | 
            
                                                                                                            
                            
            
                                    
            
            
                | 861 |  |  |         True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 862 |  |  |         >>> image.data is image.tensor | 
            
                                                                                                            
                            
            
                                    
            
            
                | 863 |  |  |         True | 
            
                                                                                                            
                            
            
                                    
            
            
                | 864 |  |  |         >>> type(image.data) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 865 |  |  |         torch.Tensor | 
            
                                                                                                            
                            
            
                                    
            
            
                | 866 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 867 |  |  |     See :class:`~torchio.Image` for more information. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 868 |  |  |     """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 869 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 870 |  |  |     def __init__(self, *args, **kwargs): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 871 |  |  |         if 'type' in kwargs and kwargs['type'] != INTENSITY: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 872 |  |  |             raise ValueError('Type of ScalarImage is always torchio.INTENSITY') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 873 |  |  |         kwargs.update({'type': INTENSITY}) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 874 |  |  |         super().__init__(*args, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 875 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 876 |  |  |     def hist(self, **kwargs) -> None: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 877 |  |  |         """Plot histogram.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 878 |  |  |         from ..visualization import plot_histogram | 
            
                                                                                                            
                            
            
                                    
            
            
                | 879 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 880 |  |  |         x = self.data.flatten().numpy() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 881 |  |  |         plot_histogram(x, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 882 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 883 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 884 |  |  | class LabelMap(Image): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 885 |  |  |     """Image whose pixel values represent segmentation labels. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 886 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 887 |  |  |     A sequence of paths to 3D images can be passed to create a 4D image. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 888 |  |  |     This is useful to create a | 
            
                                                                                                            
                            
            
                                    
            
            
                | 889 |  |  |     `tissue probability map (TPM) <https://andysbrainbook.readthedocs.io/en/latest/SPM/SPM_Short_Course/SPM_04_Preprocessing/04_SPM_Segmentation.html#tissue-probability-maps>`, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 890 |  |  |     which contains the probability of each voxel belonging to a certain tissue type, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 891 |  |  |     or to create a label map with overlapping labels. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 892 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 893 |  |  |     Intensity transforms are not applied to these images. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 894 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 895 |  |  |     Nearest neighbor interpolation is always used to resample label maps, | 
            
                                                                                                            
                            
            
                                    
            
            
                | 896 |  |  |     independently of the specified interpolation type in the transform | 
            
                                                                                                            
                            
            
                                    
            
            
                | 897 |  |  |     instantiation. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 898 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 899 |  |  |     Example: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 900 |  |  |         >>> import torch | 
            
                                                                                                            
                            
            
                                    
            
            
                | 901 |  |  |         >>> import torchio as tio | 
            
                                                                                                            
                            
            
                                    
            
            
                | 902 |  |  |         >>> binary_tensor = torch.rand(1, 128, 128, 68) > 0.5 | 
            
                                                                                                            
                            
            
                                    
            
            
                | 903 |  |  |         >>> label_map = tio.LabelMap(tensor=binary_tensor)  # from a tensor | 
            
                                                                                                            
                            
            
                                    
            
            
                | 904 |  |  |         >>> label_map = tio.LabelMap('t1_seg.nii.gz')  # from a file | 
            
                                                                                                            
                            
            
                                    
            
            
                | 905 |  |  |         >>> # Create a 4D tissue probability map from different 3D images | 
            
                                                                                                            
                            
            
                                    
            
            
                | 906 |  |  |         >>> tissues = 'gray_matter.nii.gz', 'white_matter.nii.gz', 'csf.nii.gz' | 
            
                                                                                                            
                            
            
                                    
            
            
                | 907 |  |  |         >>> tpm = tio.LabelMap(tissues) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 908 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 909 |  |  |     See :class:`~torchio.Image` for more information. | 
            
                                                                                                            
                            
            
                                    
            
            
                | 910 |  |  |     """ | 
            
                                                                                                            
                            
            
                                    
            
            
                | 911 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 912 |  |  |     def __init__(self, *args, **kwargs): | 
            
                                                                                                            
                            
            
                                    
            
            
                | 913 |  |  |         if 'type' in kwargs and kwargs['type'] != LABEL: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 914 |  |  |             raise ValueError('Type of LabelMap is always torchio.LABEL') | 
            
                                                                                                            
                            
            
                                    
            
            
                | 915 |  |  |         kwargs.update({'type': LABEL}) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 916 |  |  |         super().__init__(*args, **kwargs) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 917 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 918 |  |  |     def count_nonzero(self) -> int: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 919 |  |  |         """Get the number of voxels that are not 0.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 920 |  |  |         return int(self.data.count_nonzero().item()) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 921 |  |  |  | 
            
                                                                                                            
                            
            
                                    
            
            
                | 922 |  |  |     def count_labels(self) -> dict[int, int]: | 
            
                                                                                                            
                            
            
                                    
            
            
                | 923 |  |  |         """Get the number of voxels in each label.""" | 
            
                                                                                                            
                            
            
                                    
            
            
                | 924 |  |  |         values_list = self.data.flatten().tolist() | 
            
                                                                                                            
                            
            
                                    
            
            
                | 925 |  |  |         counter = Counter(values_list) | 
            
                                                                                                            
                            
            
                                    
            
            
                | 926 |  |  |         counts = {label: counter[label] for label in sorted(counter)} | 
            
                                                                                                            
                                                                
            
                                    
            
            
                | 927 |  |  |         return counts | 
            
                                                        
            
                                    
            
            
                | 928 |  |  |  |