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# coding=utf-8 |
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import tensorflow as tf |
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import tensorflow.keras.layers as tfkl |
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import deepreg.model.layer_util |
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from deepreg.model import layer |
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from deepreg.model.backbone.interface import Backbone |
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from deepreg.registry import REGISTRY |
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@REGISTRY.register_backbone(name="unet") |
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class UNet(Backbone): |
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""" |
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Class that implements an adapted 3D UNet. |
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Reference: |
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- O. Ronneberger, P. Fischer, and T. Brox, |
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“U-net: Convolutional networks for biomedical image segmentation,”, |
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Lecture Notes in Computer Science, 2015, vol. 9351, pp. 234–241. |
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https://arxiv.org/abs/1505.04597 |
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""" |
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def __init__( |
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self, |
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image_size: tuple, |
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out_channels: int, |
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num_channel_initial: int, |
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depth: int, |
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out_kernel_initializer: str, |
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out_activation: str, |
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pooling: bool = True, |
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concat_skip: bool = False, |
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control_points: (tuple, None) = None, |
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name: str = "Unet", |
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**kwargs, |
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): |
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""" |
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Initialise UNet. |
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:param image_size: (dim1, dim2, dim3), dims of input image. |
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:param out_channels: number of channels for the output |
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:param num_channel_initial: number of initial channels |
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:param depth: input is at level 0, bottom is at level depth |
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:param out_kernel_initializer: kernel initializer for the last layer |
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:param out_activation: activation at the last layer |
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:param pooling: for downsampling, use non-parameterized |
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pooling if true, otherwise use conv3d |
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:param concat_skip: when upsampling, concatenate skipped |
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tensor if true, otherwise use addition |
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:param control_points: specify the distance between control points (in voxels). |
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:param name: name of the backbone. |
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:param kwargs: additional arguments. |
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""" |
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super().__init__( |
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image_size=image_size, |
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out_channels=out_channels, |
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num_channel_initial=num_channel_initial, |
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out_kernel_initializer=out_kernel_initializer, |
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out_activation=out_activation, |
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name=name, |
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**kwargs, |
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) |
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# init layer variables |
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num_channels = [num_channel_initial * (2 ** d) for d in range(depth + 1)] |
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self._num_channel_initial = num_channel_initial |
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self._depth = depth |
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self._concat_skip = concat_skip |
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self._downsample_convs = [] |
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self._downsample_pools = [] |
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tensor_shape = image_size |
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self._tensor_shapes = [tensor_shape] |
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for d in range(depth): |
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downsample_conv = tf.keras.Sequential( |
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[ |
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layer.Conv3dBlock( |
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filters=num_channels[d], kernel_size=3, padding="same" |
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), |
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layer.ResidualConv3dBlock( |
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filters=num_channels[d], kernel_size=3, padding="same" |
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), |
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] |
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) |
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if pooling: |
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downsample_pool = tfkl.MaxPool3D(pool_size=2, strides=2, padding="same") |
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else: |
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downsample_pool = layer.Conv3dBlock( |
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filters=num_channels[d], kernel_size=3, strides=2, padding="same" |
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) |
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tensor_shape = tuple((x + 1) // 2 for x in tensor_shape) |
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self._downsample_convs.append(downsample_conv) |
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self._downsample_pools.append(downsample_pool) |
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self._tensor_shapes.append(tensor_shape) |
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self._bottom_conv3d = layer.Conv3dBlock( |
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filters=num_channels[depth], kernel_size=3, padding="same" |
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) |
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self._bottom_res3d = layer.ResidualConv3dBlock( |
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filters=num_channels[depth], kernel_size=3, padding="same" |
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) |
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self._upsample_deconvs = [] |
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self._upsample_convs = [] |
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for d in range(depth): |
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padding = deepreg.model.layer_util.deconv_output_padding( |
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input_shape=self._tensor_shapes[d + 1], |
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output_shape=self._tensor_shapes[d], |
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kernel_size=3, |
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stride=2, |
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padding="same", |
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) |
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upsample_deconv = layer.Deconv3dBlock( |
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filters=num_channels[d], |
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output_padding=padding, |
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kernel_size=3, |
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strides=2, |
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padding="same", |
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) |
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upsample_conv = tf.keras.Sequential( |
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[ |
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layer.Conv3dBlock( |
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filters=num_channels[d], kernel_size=3, padding="same" |
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), |
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layer.ResidualConv3dBlock( |
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filters=num_channels[d], kernel_size=3, padding="same" |
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), |
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] |
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) |
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self._upsample_deconvs.append(upsample_deconv) |
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self._upsample_convs.append(upsample_conv) |
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self._output_conv3d = tf.keras.Sequential( |
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[ |
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tfkl.Conv3D( |
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filters=out_channels, |
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kernel_size=3, |
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strides=1, |
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padding="same", |
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kernel_initializer=out_kernel_initializer, |
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activation=out_activation, |
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), |
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layer.Resize3d(shape=image_size), |
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] |
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) |
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self.resize = ( |
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layer.ResizeCPTransform(control_points) |
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if control_points is not None |
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else False |
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) |
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self.interpolate = ( |
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layer.BSplines3DTransform(control_points, image_size) |
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if control_points is not None |
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else False |
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) |
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def call(self, inputs: tf.Tensor, training=None, mask=None) -> tf.Tensor: |
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""" |
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Builds graph based on built layers. |
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:param inputs: shape = [batch, f_dim1, f_dim2, f_dim3, in_channels] |
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:param training: |
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:param mask: |
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:return: shape = [batch, f_dim1, f_dim2, f_dim3, out_channels] |
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""" |
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down_sampled = inputs |
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# down sample |
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skips = [] |
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for d_var in range(self._depth): # level 0 to D-1 |
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skip = self._downsample_convs[d_var](inputs=down_sampled, training=training) |
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down_sampled = self._downsample_pools[d_var](inputs=skip, training=training) |
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skips.append(skip) |
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# bottom, level D |
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up_sampled = self._bottom_res3d( |
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inputs=self._bottom_conv3d(inputs=down_sampled, training=training), |
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training=training, |
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) |
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# up sample, level D-1 to 0 |
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for d_var in range(self._depth - 1, -1, -1): |
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up_sampled = self._upsample_deconvs[d_var]( |
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inputs=up_sampled, training=training |
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) |
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if self._concat_skip: |
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up_sampled = tf.concat([up_sampled, skips[d_var]], axis=4) |
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else: |
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up_sampled = up_sampled + skips[d_var] |
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up_sampled = self._upsample_convs[d_var]( |
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inputs=up_sampled, training=training |
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) |
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# output |
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output = self._output_conv3d(inputs=up_sampled, training=training) |
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if self.resize: |
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output = self.resize(output) |
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output = self.interpolate(output) |
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return output |
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